Division of Molecular Medicine and Gene Therapy
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- 2019
- Endothelial protein C receptor (EPCR) expression marks human fetal liver hematopoietic stem cells
- Ex Vivo Expansion of Human Hematopoietic Stem Cells
- Protein biomarkers associated with pain mechanisms in osteoarthritis
- The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis
- 2018
- Programming Blood Cell Fates. Insights from Direct Lineage Conversion and Development
- Direct reprogramming of fibroblasts into antigen-presenting dendritic cells
- Direct role of FLT3 in regulation of early lymphoid progenitors
- Identification of intrinsic regulators in normal and malignant human hematopoiesis. An RNA-interference approach.
- Osteoclasts degrade bone and cartilage knee joint compartments through different resorption processes
- Roles of PDZ-dependent Interactions and N-glycosylation in G Protein-coupled Estrogen Receptor 1 (GPER1)/GPR30-mediated Stimulation of ERK1/2 Activity
- Development of Novel Therapies, Models, and Biomarkers for Osteoclast-Related Diseases
- Regulation of unfolded protein response in hematopoietic stem cells
- A new genetic tool to improve immune-compromised mouse models : Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines
- Transient inhibition of NF-κB signaling enhances ex vivo propagation of human hematopoietic stem cells
- Cohesin in haematopoiesis and leukaemia
- Fetal gene therapy for neurodegenerative disease of infants
- Direct Lineage Reprogramming of Adult Mouse Fibroblast to Erythroid Progenitors
- On new and current treatments for Diamond-Blackfan anemia
- Targeting NSG Mice Engrafting Cells with a Clinically Applicable Lentiviral Vector Corrects Osteoclasts in Infantile Malignant Osteopetrosis
- Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6 dependent manner
- Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming
- Pentaisomaltose, an Alternative to DMSO. Engraftment of Cryopreserved Human CD34+ Cells in Immunodeficient NSG Mice
- Prospective evaluation of a combination of fungal biomarkers for the diagnosis of invasive fungal disease in high-risk haematology patients
- Tipping clonal hematopoiesis into transformation
- The Role of Hepatic Leukemia Factor in Hematopoiesis
- In vitro tumorigenic assay : colony forming assay for cancer stem cells
- 2017
- Forward RNAi screens in human hematopoietic stem cells
- The Effects of Genetic and Epigenetic Variation on Human Pluripotent Stem Cell Differentiation
- Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia
- The stem cell regulator PEDF is dispensable for maintenance and function of hematopoietic stem cells
- Forced expression of human macrophage colony-stimulating factor in CD34+ cells promotes monocyte differentiation in vitro and in vivo but blunts osteoclastogenesis in vitro
- Cytohesin 1 regulates homing and engraftment of human hematopoietic stem and progenitor cells
- Direct lineage reprogramming : a useful addition to the blood cell research toolbox
- Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells
- Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration
- Direct conversion of human fibroblasts to functional excitatory cortical neurons integrating into human neural networks
- The impact of socio-economic factors on treatment choice and mortality in chronic myeloid leukaemia
- Roscoe Owen Brady, MD : Remembrances of co-investigators and colleagues
- Management and monitoring recommendations for the use of eliglustat in adults with type 1 Gaucher disease in Europe
- Induction of the 5S RNP–Mdm2–p53 ribosomal stress pathway delays the initiation but fails to eradicate established murine acute myeloid leukemia
- Kronisk myeloisk leukemi : förebild för målstyrd terapi - Revolutionerande överlevnadsvinster med definitiv bot i sikte och kraftigt förbättrad hälsoekonomi
- Term amniotic fluid : An unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications
- Kronisk myeloisk leukemi : Förebild för målstyrd terapi
- Signaling via Smad2 and Smad3 is dispensable for adult murine hematopoietic stem cell function in vivo
- Barcodes show family trees in ALL
- Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor
- Erythroid Culture Based on Differentiation of Progenitor Cells from Leftover Buffy Coats Produced in the Reveos Automated Blood Processing System
- Technical considerations for the use of CRISPR/Cas9 in hematology research
- Single-Cell Analysis Identifies Distinct Stages of Human Endothelial-to-Hematopoietic Transition
- Advanced phase chronic myeloid leukaemia (CML) in the tyrosine kinase inhibitor era - a report from the Swedish CML register