Division of Molecular Medicine and Gene Therapy
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- 2018
- Identification of intrinsic regulators in normal and malignant human hematopoiesis. An RNA-interference approach.
- Osteoclasts degrade bone and cartilage knee joint compartments through different resorption processes
- Programming Blood Cell Fates. Insights from Direct Lineage Conversion and Development
- Development of Novel Therapies, Models, and Biomarkers for Osteoclast-Related Diseases
- Regulation of unfolded protein response in hematopoietic stem cells
- A new genetic tool to improve immune-compromised mouse models : Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines
- Cohesin in haematopoiesis and leukaemia
- Fetal gene therapy for neurodegenerative disease of infants
- Protein biomarkers associated with pain mechanisms in osteoarthritis
- Targeting NSG Mice Engrafting Cells with a Clinically Applicable Lentiviral Vector Corrects Osteoclasts in Infantile Malignant Osteopetrosis
- Pentaisomaltose, an Alternative to DMSO. Engraftment of Cryopreserved Human CD34+ Cells in Immunodeficient NSG Mice
- Tipping clonal hematopoiesis into transformation
- Prospective evaluation of a combination of fungal biomarkers for the diagnosis of invasive fungal disease in high-risk haematology patients
- The Role of Hepatic Leukemia Factor in Hematopoiesis
- In vitro tumorigenic assay : colony forming assay for cancer stem cells
- Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6 dependent manner
- 2017
- Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells
- Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration
- Direct conversion of human fibroblasts to functional excitatory cortical neurons integrating into human neural networks
- The stem cell regulator PEDF is dispensable for maintenance and function of hematopoietic stem cells
- The Effects of Genetic and Epigenetic Variation on Human Pluripotent Stem Cell Differentiation
- Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia
- Forced expression of human macrophage colony-stimulating factor in CD34+ cells promotes monocyte differentiation in vitro and in vivo but blunts osteoclastogenesis in vitro
- Cytohesin 1 regulates homing and engraftment of human hematopoietic stem and progenitor cells
- Forward RNAi screens in human hematopoietic stem cells
- Direct lineage reprogramming : a useful addition to the blood cell research toolbox
- The impact of socio-economic factors on treatment choice and mortality in chronic myeloid leukaemia
- Roscoe Owen Brady, MD : Remembrances of co-investigators and colleagues
- Management and monitoring recommendations for the use of eliglustat in adults with type 1 Gaucher disease in Europe
- Induction of the 5S RNP–Mdm2–p53 ribosomal stress pathway delays the initiation but fails to eradicate established murine acute myeloid leukemia
- Barcodes show family trees in ALL
- Kronisk myeloisk leukemi : förebild för målstyrd terapi - Revolutionerande överlevnadsvinster med definitiv bot i sikte och kraftigt förbättrad hälsoekonomi
- Term amniotic fluid : An unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications
- Kronisk myeloisk leukemi : Förebild för målstyrd terapi
- Signaling via Smad2 and Smad3 is dispensable for adult murine hematopoietic stem cell function in vivo
- Single-Cell Analysis Identifies Distinct Stages of Human Endothelial-to-Hematopoietic Transition
- Advanced phase chronic myeloid leukaemia (CML) in the tyrosine kinase inhibitor era - a report from the Swedish CML register
- Erythroid Culture Based on Differentiation of Progenitor Cells from Leftover Buffy Coats Produced in the Reveos Automated Blood Processing System
- Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor
- Technical considerations for the use of CRISPR/Cas9 in hematology research
- Development of novel therapies for Diamond-Blackfan Anemia
- Reactive Oxygen Species Impair the Function of CD90+ Hematopoietic Progenitors Generated from Human Pluripotent Stem Cells
- Modelling Human Developmental Hematopoiesis. Towards in vitro Generation of Human Hematopoietic Stem Cells
- Single-cell molecular analysis defines therapy response and immunophenotype of stem cell subpopulations in CML
- Increased proportion of mature NK cells is associated with successful imatinib discontinuation in chronic myeloid leukemia
- No increased prevalence of malignancies among first-degree relatives of 800 patients with chronic myeloid leukemia : A population-based study in Sweden
- 2016
- The putative tumor suppressor gene EphA7 is a novel BMI-1 target
- IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models
- The european hematology association roadmap for european hematology research : A consensus document
- BCAT1, a key prognostic predictor of hepatocellular carcinoma, promotes cell proliferation and induces chemoresistance to cisplatin