Translational Genomic and Functional Studies of Leukemia

Mark Sub-Nanomolar Detection of Oligonucleotides Using Molecular Beacons Immobilized on Lightguiding Nanowires

Johansson, Therese B. ^LU ; Davtyan, Rubina ^LU ; Valderas-Gutiérrez, Julia ^LU

; Gonzalez Rodriguez, Adrian ^LU ; Agnarsson, Björn ; Munita, Roberto ^LU ; Fioretos, Thoas ^LU ; Lilljebjörn, Henrik ^LU

; Linke, Heiner ^LU

and Höök, Fredrik ^LU , et al. (2024) In Nanomaterials 14(5).

Contribution to journal › Article

Mark Current and emerging sequencing-based tools for precision cancer medicine

Edsjö, Anders ^LU ; Gisselsson, David ^LU ; Staaf, Johan ^LU

; Holmquist, Louise ; Fioretos, Thoas ^LU ; Cavelier, Lucia and Rosenquist, Richard (2024) In Molecular Aspects of Medicine 96.

Contribution to journal › Scientific review

Mark IL1RAP is expressed in several subtypes of pediatric acute lymphoblastic leukemia and can be used as a target to eliminate ETV6::RUNX1-positive leukemia cells in preclinical models.

Ågerstam, Helena ^LU ; Lilljebjörn, Henrik ^LU

; Rissler, Marianne ^LU ; Sandén, Carl ^LU and Fioretos, Thoas ^LU (2023) In Haematologica 108(2). p.599-604

Contribution to journal › Article

Mark Building a precision medicine infrastructure at a national level: The Swedish experience

Edsjö, Anders ^LU ; Lindstrand, Anna ; Gisselsson Nord, David ^LU ; Orvelid-Mölling, Paula ; Friedman, Mikaela ; Cavelier, Lucia ; Johansson, Maria ^LU ; Ehrencrona, Hans ^LU

; Fagerqvist, Therese and Strid, Tobias , et al. (2023) In Cambridge Prisms: Precision Medicine 1.

Contribution to journal › Scientific review

Mark The complement receptor C3AR constitutes a novel therapeutic target in NPM1-mutated AML

von Palffy, Sofia ^LU ; Thorsson, Hanna ^LU ; Peña-Martínez, Pablo ^LU ; Puente-Moncada, Noelia ^LU ; Sandén, Carl ^LU ; Blom, Anna M ^LU

; Henningsson, Rasmus ^LU ; Juliusson, Gunnar ^LU ; King, Ben ^LU

and Landberg, Niklas ^LU

, et al. (2023) In Blood Advances 7(7). p.1204-1218

Contribution to journal › Article

Mark Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity

Rodriguez-Zabala, Maria ^LU ; Ramakrishnan, Ramprasad ^LU ; Reinbach, Katrin ^LU ; Ghosh, Somadri ^LU

; Oburoglu, Leal ^LU

; Falqués-Costa, Antoni ; Bellamkonda, Kishan ^LU ; Ehinger, Mats ^LU ; Peña-Martínez, Pablo ^LU and Puente-Moncada, Noelia ^LU , et al. (2023) In Blood Advances 7(18). p.5382-5395

Contribution to journal › Article

Mark Novel precision medicine approaches and treatment strategies in hematological malignancies

Rosenquist, Richard ; Bernard, Elsa ; Erkers, Tom ; Scott, David W. ; Itzykson, Raphael ; Rousselot, Philippe ; Soulier, Jean ; Hutchings, Martin ; Östling, Päivi and Cavelier, Lucia , et al. (2023) In Journal of Internal Medicine 294(4). p.413-436

Contribution to journal › Scientific review

Mark Feasibility to use whole-genome sequencing as a sole diagnostic method to detect genomic aberrations in pediatric B-cell acute lymphoblastic leukemia

Rezayee, Fatemah ; Eisfeldt, Jesper ; Skaftason, Aron ; Öfverholm, Ingegerd ; Sayyab, Shumaila ; Syvänen, Ann Christine ; Maqbool, Khurram ; Lilljebjörn, Henrik ^LU

; Johansson, Bertil ^LU and Olsson-Arvidsson, Linda ^LU , et al. (2023) In Frontiers in Oncology 13.

Contribution to journal › Article

Mark Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia

Krali, Olga ; Marincevic-Zuniga, Yanara ; Arvidsson, Gustav ; Enblad, Anna Pia ; Lundmark, Anders ; Sayyab, Shumaila ; Zachariadis, Vasilios ; Heinäniemi, Merja ; Suhonen, Janne and Oksa, Laura , et al. (2023) In NPJ precision oncology 7(1).

Contribution to journal › Article

Mark Transcriptomics paving the way for improved diagnostics and precision medicine of acute leukemia

Lilljebjörn, Henrik ^LU

; Orsmark-Pietras, Christina ^LU ; Mitelman, Felix ^LU

; Hagström-Andersson, Anna ^LU

and Fioretos, Thoas ^LU (2022) In Seminars in Cancer Biology 84. p.40-49

Contribution to journal › Article

Mark N-terminus DUX4-immunohistochemistry is a reliable methodology for the diagnosis of DUX4-fused B-lymphoblastic leukemia/lymphoma (N-terminus DUX4 IHC for DUX4-fused B-ALL)

Siegele, Bradford J. ; Stemmer-Rachamimov, Anat O. ; Lilljebjorn, Henrik ^LU

; Fioretos, Thoas ^LU ; Winters, Amanda C. ; Dal Cin, Paola ; Treece, Amy ; Gaskell, Alisa and Nardi, Valentina (2022) In Genes Chromosomes and Cancer 61(8). p.449-458

Contribution to journal › Article

Mark Duplex Sequencing Uncovers Recurrent Low-frequency Cancer-associated Mutations in Infant and Childhood KMT2A-rearranged Acute Leukemia

Pilheden, Mattias ^LU ; Ahlgren, Louise ^LU ; Hyrenius-Wittsten, Axel ^LU ; Gonzalez-Pena, Veronica ; Sturesson, Helena ^LU ; Hansen Marquart, Hanne Vibeke ; Lausen, Birgitte ; Castor, Anders ^LU ; Pronk, Cornelis Jan and Barbany, Gisela , et al. (2022) In HemaSphere 6(10). p.1-8

Contribution to journal › Article

Mark Trailblazing precision medicine in Europe : A joint view by Genomic Medicine Sweden and the Centers for Personalized Medicine, ZPM, in Germany

Stenzinger, Albrecht ; Edsjö, Anders ^LU ; Ploeger, Carolin ; Friedman, Mikaela ; Fröhling, Stefan ; Wirta, Valtteri ; Seufferlein, Thomas ; Botling, Johan ; Duyster, Justus and Akhras, Michael , et al. (2022) In Seminars in Cancer Biology 84. p.242-254

Contribution to journal › Article

Mark A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development

Johansson, Pia A ^LU ; Brattås, Per Ludvik ^LU ; Douse, Christopher H ^LU ; Hsieh, PingHsun ; Adami, Anita ^LU ; Pontis, Julien ; Grassi, Daniela ^LU ; Garza, Raquel ^LU

; Sozzi, Edoardo ^LU

and Cataldo, Rodrigo ^LU

, et al. (2022) In Cell Stem Cell 29(1). p.8-69

Contribution to journal › Article

Mark A Study Protocol for Validation and Implementation of Whole-Genome and -Transcriptome Sequencing as a Comprehensive Precision Diagnostic Test in Acute Leukemias

Berglund, Eva ; Barbany, Gisela ; Orsmark-Pietras, Christina ^LU ; Fogelstrand, Linda ; Abrahamsson, Jonas ; Golovleva, Irina ; Hallböök, Helene ; Lazarevic, Vladimir ^LU ; Levin, Lars Åke and Nordlund, Jessica , et al. (2022) In Frontiers in Medicine 9. p.1-9

Contribution to journal › Article

Mark High CD34 surface expression in BCP-ALL predicts poor induction therapy response and is associated with altered expression of genes related to cell migration and adhesion

Modvig, Signe ; Wernersson, Rasmus ; Øbro, Nina Friesgaard ; Olsen, Lars Rønn ; Christensen, Claus ; Rosthøj, Susanne ; Degn, Matilda ; Jürgensen, Gitte Wullf ; Madsen, Hans O. and Albertsen, Birgitte Klug , et al. (2022) In Molecular Oncology 16(10). p.2015-2030

Contribution to journal › Article

Mark Inducing synthetic lethality for selective targeting of acute myeloid leukemia cells harboring STAG2 mutations

Subramaniam, Agatheeswaran ^LU ; Sandén, Carl ^LU ; Moura-Castro, Larissa ^LU

; Žemaitis, Kristijonas ^LU ; Schmiderer, Ludwig ^LU ; Baudet, Aurelie ^LU ; Bäckström, Alexandra ^LU ; Arvidsson, Elin ^LU

; Hultmark, Simon ^LU and Miharada, Natsumi ^LU , et al. (2022) In Haematologica 107(9). p.2271-2275

Contribution to journal › Letter

Mark Application of precision medicine in clinical routine in haematology—Challenges and opportunities

Wästerlid, Tove ^LU ; Cavelier, Lucia ; Haferlach, Claudia ; Konopleva, Marina ; Fröhling, Stefan ; Östling, Päivi ; Bullinger, Lars ; Fioretos, Thoas ^LU and Smedby, Karin E. (2022) In Journal of Internal Medicine 292(2). p.243-261

Contribution to journal › Scientific review

Mark Implementing precision medicine in a regionally organized healthcare system in Sweden

Fioretos, Thoas ^LU ; Wirta, Valtteri ; Cavelier, Lucia ; Berglund, Eva ; Friedman, Mikaela ; Akhras, Michael ; Botling, Johan ; Ehrencrona, Hans ^LU

; Engstrand, Lars and Helenius, Gisela , et al. (2022) In Nature Medicine 28(10). p.1980-1982

Contribution to journal › Letter

Mark Transcriptional profiling demonstrates altered characteristics of CD8 + cytotoxic T-cells and regulatory T-cells in TP53-mutated acute myeloid leukemia

Abolhalaj, Milad ^LU ; Sincic, Viktor ^LU ; Lilljebjörn, Henrik ^LU

; Sandén, Carl ^LU ; Aab, Alar ^LU ; Hägerbrand, Karin ^LU ; Ellmark, Peter ^LU ; Borrebaeck, Carl ^LU ; Fioretos, Thoas ^LU and Lundberg, Kristina ^LU (2022) In Cancer Medicine 11(15). p.3023-3032

Contribution to journal › Article

Mark Why B(-)other? About the gap of unknowns in ALL

Fioretos, Thoas ^LU (2022) In Blood 139(24). p.3455-3457

Contribution to journal › Debate/Note/Editorial

Mark Combinatorial molecule screening identifies a novel diterpene and the BET inhibitor CPI-203 as differentiation inducers of primary acute myeloid leukemia cells

Hultmark, Simon ^LU ; Baudet, Aurélie ^LU ; Schmiderer, Ludwig ^LU ; Prabhala, Pavan ^LU ; Palma-Tortosa, Sara ^LU ; Sandén, Carl ^LU ; Fioretos, Thoas ^LU ; Sasidharan, Rajkumar ; Larsson, Christer ^LU and Lehmann, Sören , et al. (2021) In Haematologica 106(10).

Contribution to journal › Article

Mark Targeting GLUT1 in acute myeloid leukemia to overcome cytarabine resistance

Åbacka, Hannah ^LU

; Hansen, Jesper S ^LU ; Huang, Peng ^LU ; Venskutonytė, Raminta ^LU ; Hyrenius-Wittsten, Axel ^LU ; Poli, Giulio ; Tuccinardi, Tiziano ; Granchi, Carlotta ; Minutolo, Filippo and Hagström-Andersson, Anna K ^LU

, et al. (2021) In Haematologica 106(4). p.1163-1166

Contribution to journal › Article

Mark Clinical and genomic characterization of patients diagnosed with the provisional entity Acute myeloid leukemia with BCR-ABL1, a Swedish population-based study

Orsmark-Pietras, Christina ^LU ; Landberg, Niklas ^LU

; Lorenz, Fryderyk ; Uggla, Bertil ; Höglund, Martin ; Lehmann, Sören ; Derolf, Åsa ; Deneberg, Stefan ; Antunovic, Petar and Cammenga, Jörg ^LU , et al. (2021) In Genes, Chromosomes and Cancer 60(6). p.426-433

Contribution to journal › Article

Mark Receptors and Regulators of Myeloid Leukemia

von Palffy, Sofia ^LU (2021) In Lund University, Faculty of Medicine Doctoral Dissertation Series

Thesis › Doctoral thesis (compilation)

Mark Single-cell sequencing in translational cancer research and challenges to meet clinical diagnostic needs

Pfisterer, Ulrich ^LU ; Bräunig, Julia ^LU ; Brattås, Per ^LU ; Heidenblad, Markus ^LU ; Karlsson, Göran ^LU and Fioretos, Thoas ^LU (2021) In Genes, Chromosomes and Cancer 60(7). p.504-524

Contribution to journal › Scientific review

Mark Precisionsmedicin standard vid flera hematologiska sjukdomar

Hellström Lindberg, Eva ; Cavelier, Lucia ; Cammenga, Jörg ^LU ; Andersson, Per Ola ; Fioretos, Thoas ^LU and Rosenquist, Richard (2021) In Lakartidningen 118.

Contribution to journal › Article

Mark Evolution: lab-grown ‘mini brains’ suggest one mutation might have rewired the human mind

Jimenez Ferrer Carrillo, Itzia ^LU and Brattås, Per ^LU (2021) In The Conversation

Contribution to specialist publication or newspaper › Specialist publication article

Mark Clonal competition within complex evolutionary hierarchies shapes AML over time

Sandén, Carl ^LU ; Lilljebjörn, Henrik ^LU

; Orsmark Pietras, Christina ^LU ; Henningsson, Rasmus ^LU ; Saba, Karim H. ^LU

; Landberg, Niklas ^LU

; Thorsson, Hanna ^LU ; von Palffy, Sofia ^LU ; Peña-Martinez, Pablo ^LU and Högberg, Carl ^LU , et al. (2020) In Nature Communications 11(1).

Contribution to journal › Article

Mark 13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking

Yang, Minjun ^LU ; Safavi, Setareh ^LU ; Woodward, Eleanor L ^LU ; Duployez, Nicolas ; Olsson-arvidsson, Linda ; Ungerbäck, Jonas ^LU ; Sigvardsson, Mikael ^LU ; Zaliova, Marketa ; Zuna, Jan and Fioretos, Thoas ^LU , et al. (2020) In Blood 136(8). p.946-956

Contribution to journal › Article

Mark Cell Surface Markers as Therapeutic Targets in Myeloid Leukemia

Landberg, Niklas ^LU

(2020) In Lund University, Faculty of Medicine Doctoral Dissertation Series

Thesis › Doctoral thesis (compilation)

Mark A dynamic mutational landscape associated with an inter-regionally diverse immune response in malignant rhabdoid tumour

Yasui, Hiroaki ^LU ; Valind, Anders ^LU

; Karlsson, Jenny ^LU ; Pietras, Christina ^LU ; Jansson, Caroline ^LU ; Wille, Joakim ^LU ; Romerius, Patrik ^LU ; Backman, Torbjörn ^LU and Gisselsson, David ^LU (2020) In Journal of Pathology 252(1). p.22-28

Contribution to journal › Article

Mark A high-content cytokine screen identifies myostatin propeptide as a positive regulator of primitive chronic myeloid leukemia cells

von Palffy, Sofia ^LU ; Landberg, Niklas ^LU

; Sandén, Carl ^LU ; Zacharaki, Dimitra ^LU ; Shah, Mansi ; Nakamichi, Naoto ; Hansen, Nils ^LU ; Askmyr, Maria ^LU ; Lilljebjörn, Henrik ^LU

and Rissler, Marianne ^LU , et al. (2020) In Haematologica 105(8). p.2095-2104

Contribution to journal › Article

Mark CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia

Ramakrishnan, Ramprasad ^LU ; Peña-Martínez, Pablo ^LU ; Agarwal, Puneet ; Rodriguez-Zabala, Maria ^LU ; Chapellier, Marion ^LU ; Högberg, Carl ^LU ; Eriksson, Mia ^LU ; Yudovich, David ^LU ; Shah, Mansi and Ehinger, Mats ^LU , et al. (2020) In Cell Reports 31(8).

Contribution to journal › Article

Mark Transcriptomic profiling of T-cell populations in non-muscle invasive and muscle invasive bladder cancer.

Sincic, Viktor ^LU ; Abolhalaj, Milad ^LU ; Lilljebjörn, Henrik ^LU

; Aab, Alar ^LU ; Hägerbrand, Karin ^LU ; Ellmark, Peter ^LU ; Fioretos, Thoas ^LU ; Borrebaeck, Carl ^LU ; Liedberg, Fredrik ^LU and Lundberg, Kristina ^LU (2020) The Society for Immunotherapy of Cancer's (SITC) 35th annual meeting In Journal for ImmunoTherapy of Cancer 8(Suppl. 3).

Contribution to journal › Published meeting abstract

Mark Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells

Chapellier, Marion ^LU ; Peña-Martínez, Pablo ^LU ; Ramakrishnan, Ramprasad ^LU ; Eriksson, Mia ^LU ; Safaee-Talkhoncheh, Mehrnaz ^LU ; Orsmark-Pietras, Christina ^LU ; Lilljebjörn, Henrik ^LU

; Högberg, Carl ^LU ; Hagström-Andersson, Anna ^LU

and Fioretos, Thoas ^LU , et al. (2019) In Haematologica 104(10). p.2006-2016

Contribution to journal › Article

Mark Recombinant dermatan sulfate is a potent activator of heparin cofactor II-dependent inhibition of thrombin

Tykesson, Emil ^LU

; Maccarana, Marco ^LU ; Thorsson, Hanna ^LU ; Liu, Jian ; Malmström, Anders ^LU

; Ellervik, Ulf ^LU and Westergren-Thorsson, Gunilla ^LU (2019) In Glycobiology 29(6). p.446-451

Contribution to journal › Article

Mark FLT3 ^N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis

Hyrenius-Wittsten, Axel ^LU ; Pilheden, Mattias ^LU ; Falqués-Costa, Antoni ; Eriksson, Mia ^LU ; Sturesson, Helena ^LU ; Schneider, Pauline ; Wander, Priscilla ; Garcia-Ruiz, Cristian ^LU ; Liu, Jian and Ågerstam, Helena ^LU , et al. (2019) In Leukemia 33(9). p.2310-2314

Contribution to journal › Letter

Mark Disseqt-distribution-based modeling of sequence space time dynamics

Henningsson, R. ^LU ; Moratorio, G. ; Bordería, A. V. ; Vignuzzi, M. and Fontes, M. ^LU (2019) In Virus Evolution 5(2).

Contribution to journal › Article

Mark Genetic profiling of a chondroblastoma-like osteosarcoma/malignant phosphaturic mesenchymal tumor of bone reveals a homozygous deletion of CDKN2A, intragenic deletion of DMD, and a targetable FN1-FGFR1 gene fusion

Saba, Karim H ^LU

; Cornmark, Louise ^LU ; Rissler, Marianne ^LU ; Fioretos, Thoas ^LU ; Åström, Kristina ; Haglund, Felix ; Rosenberg, Andrew E ; Brosjö, Otte and Nord, Karolin H ^LU (2019) In Genes, Chromosomes and Cancer 58(10). p.731-736

Contribution to journal › Article

Mark Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia

Yang, Minjun ^LU ; Vesterlund, Mattias ; Siavelis, Ioannis ; Moura-Castro, Larissa H. ^LU

; Castor, Anders ^LU ; Fioretos, Thoas ^LU ; Jafari, Rozbeh ; Lilljebjörn, Henrik ^LU

; Odom, Duncan T. and Olsson, Linda ^LU , et al. (2019) In Nature Communications 10(1).

Contribution to journal › Article

Mark PAX5 is part of a functional transcription factor network targeted in lymphoid leukemia

Okuyama, Kazuki ; Strid, Tobias ^LU ; Kuruvilla, Jacob ^LU ; Somasundaram, Rajesh ; Cristobal, Susana ; Smith, Emma ^LU ; Prasad, Mahadesh ; Fioretos, Thoas ^LU ; Lilljebjörn, Henrik ^LU

and Soneji, Shamit ^LU , et al. (2019) In PLoS Genetics 15(8).

Contribution to journal › Article

Mark CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting

Landberg, Niklas ^LU

; von Palffy, Sofia ^LU ; Askmyr, Maria ^LU ; Lilljebjörn, Henrik ^LU

; Sandén, Carl ^LU ; Rissler, Marianne ^LU ; Mustjoki, Satu ; Hjorth-Hansen, Henrik ; Richter, Johan ^LU and Ågerstam, Helena ^LU , et al. (2018) In Haematologica 103(3). p.447-455

Contribution to journal › Article

Mark Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases

Li, Jian Feng ; Dai, Yu Ting ; Lilljebjörn, Henrik ^LU

; Shen, Shu Hong ; Cui, Bo Wen ; Bai, Ling ; Liu, Yuan Fang ; Qian, Mao Xiang ; Kubota, Yasuo and Kiyoi, Hitoshi , et al. (2018) In Proceedings of the National Academy of Sciences of the United States of America 115(50). p.11711-11720

Contribution to journal › Article

Mark A field guide for cancer diagnostics using cell-free DNA : From principles to practice and clinical applications

Volckmar, Anna Lena ; Sültmann, Holger ; Riediger, Anja ; Fioretos, Thoas ^LU ; Schirmacher, Peter ; Endris, Volker ; Stenzinger, Albrecht and Dietz, Steffen (2018) In Genes Chromosomes and Cancer 57(3). p.123-139

Contribution to journal › Scientific review

Mark Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6 dependent manner

Peña, Pablo ^LU ; Eriksson, Mia ^LU ; Ramakrishnan, R ^LU ; Chapellier, M ^LU ; Högberg, Carl ^LU ; Orsmark-Pietras, C ^LU ; Richter, J ^LU ; Andersson, Anna ^LU

; Fioretos, T ^LU and Järås, M ^LU (2018) In Leukemia 32(3). p.588-596

Contribution to journal › Article

Mark Transgenic expression of human cytokines in immunodeficient mice does not facilitate myeloid expansion of BCR-ABL1 transduced human cord blood cells

Askmyr, Maria ^LU ; Von Palffy, Sofia ^LU ; Hansen, Nils ^LU ; Landberg, Niklas ^LU

; Högberg, Carl ^LU ; Rissler, Marianne ^LU ; Ågerstam, Helena ^LU and Fioretos, Thoas ^LU (2017) In PLoS ONE 12(10).

Contribution to journal › Article

Mark New oncogenic subtypes in pediatric B-cell precursor acute lymphoblastic leukemia

Lilljebjörn, Henrik ^LU

and Fioretos, Thoas ^LU (2017) In Blood 130(12). p.1395-1401

Contribution to journal › Scientific review

Mark Primary cells in BCR/FGFR1-positive 8p11 myeloproliferative syndrome are sensitive to dovitinib, ponatinib, and dasatinib

Landberg, Niklas ^LU

; Dreimane, Arta ; Rissler, Marianne ^LU ; Billström, Rolf and Ågerstam, Helena ^LU (2017) In European Journal of Haematology 99(5). p.442-448

Contribution to journal › Article

Mark Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia

Lilljebjörn, Henrik ^LU

; Henningsson, Rasmus ^LU ; Hyrenius-Wittsten, Axel ^LU ; Olsson, Linda ^LU ; Orsmark-Pietras, Christina ^LU ; Von Palffy, Sofia ^LU ; Askmyr, Maria ^LU ; Rissler, Marianne ^LU ; Schrappe, Martin and Cario, Gunnar , et al. (2016) In Nature Communications 7.

Contribution to journal › Article

Mark IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models

Ågerstam, Helena ^LU ; Hansen, Nils ^LU ; von Palffy, Sofia ^LU ; Sandén, Carl ^LU ; Reckzeh, Kristian ^LU ; Karlsson, Christine ^LU ; Lilljebjörn, Henrik ^LU

; Landberg, Niklas ^LU

; Askmyr, Maria ^LU and Högberg, Carl ^LU , et al. (2016) In Blood 128(23). p.2683-2693

Contribution to journal › Article

Mark IL1RAP expression as a measure of leukemic stem cell burden at diagnosis of chronic myeloid leukemia predicts therapy outcome.

Landberg, Niklas ^LU

; Hansen, Nils ^LU ; Askmyr, Maria ^LU ; Ågerstam, Helena ^LU ; Lassen, Carin ^LU ; Rissler, Marianne ^LU ; Hansen, H H ; Mustjoki, S ; Järås, Marcus ^LU and Richter, Johan ^LU , et al. (2015) In Leukemia 30(1). p.255-258

Contribution to journal › Article

Mark Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.

Ågerstam, Helena ^LU ; Karlsson, Christine ^LU ; Hansen, Nils ^LU ; Sandén, Carl ^LU ; Askmyr, Maria ^LU ; von Palffy, Sofia ^LU ; Högberg, Carl ^LU ; Rissler, Marianne ^LU ; Wunderlich, Mark and Juliusson, Gunnar ^LU , et al. (2015) In Proceedings of the National Academy of Sciences 112(34). p.10786-10791

Contribution to journal › Article

Mark The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.

Paulsson, Kajsa ^LU ; Lilljebjörn, Henrik ^LU

; Biloglav, Andrea ^LU ; Olsson, Linda ^LU ; Rissler, Marianne ^LU ; Castor, Anders ^LU ; Barbany, Gisela ; Fogelstrand, Linda ; Nordgren, Ann and Sjögren, Helene , et al. (2015) In Nature Genetics 47(6). p.672-676

Contribution to journal › Article

Mark The emerging complexity of gene fusions in cancer.

Mertens, Fredrik ^LU ; Johansson, Bertil ^LU ; Fioretos, Thoas ^LU and Mitelman, Felix ^LU

(2015) In Nature Reviews. Cancer 15(6). p.371-381

Contribution to journal › Scientific review

Mark Selective killing of candidate AML stem cells by antibody targeting of IL1RAP.

Askmyr, Maria ^LU ; Ågerstam, Helena ^LU ; Hansen, Nils ^LU ; Gordon, Sandra ^LU ; Arvanitakis, Alexandros ^LU ; Rissler, Marianne ^LU ; Juliusson, Gunnar ^LU ; Richter, Johan ^LU ; Järås, Marcus ^LU and Fioretos, Thoas ^LU (2013) In Blood 121(18). p.3709-3713

Contribution to journal › Article

Mark Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice

Ågerstam, Helena ^LU ; Järås, Marcus ^LU ; Andersson, Anna ^LU

; Johnels, Petra ^LU ; Hansen, Nils ^LU ; Lassen, Carin ^LU ; Rissler, Marianne ^LU ; Gisselsson Nord, David ^LU ; Olofsson, Tor ^LU and Richter, Johan ^LU , et al. (2010) In Blood 116(12). p.2103-2111

Contribution to journal › Article

Mark Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.

Järås, Marcus ^LU ; Johnels, Petra ^LU ; Hansen, Nils ^LU ; Ågerstam, Helena ^LU ; Tsapogas, Panagiotis ; Rissler, Marianne ^LU ; Lassen, Carin ^LU ; Olofsson, Tor ^LU ; Bjerrum, Ole Weis and Richter, Johan ^LU , et al. (2010) In Proceedings of the National Academy of Sciences 107(37). p.16280-16285

Contribution to journal › Article

Mark Molecular signatures in childhood acute leukemia and their correlations to expression patterns in normal hematopoietic subpopulations.

Andersson, Anna ^LU

; Olofsson, Tor ^LU ; Lindgren, David ^LU ; Nilsson, Björn ^LU ; Ritz, Cecilia ^LU ; Edén, Patrik ^LU ; Lassen, Carin ^LU ; Råde, Johan ^LU ; Fontes, Magnus ^LU and Mörse, Helena ^LU , et al. (2005) In Proceedings of the National Academy of Sciences 102(52). p.19069-19074

Contribution to journal › Article

Lund University Publications

LUND UNIVERSITY LIBRARIES

Translational Genomic and Functional Studies of Leukemia

Embed this list