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- 2019
- Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus
- 2018
- Smoking reduces the efficacy of belimumab in mucocutaneous lupus
- Active NET formation in Libman–Sacks endocarditis without antiphospholipid antibodies : A dramatic onset of systemic lupus erythematosus
- DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus
- The non-haemostatic role of platelets in systemic lupus erythematosus
- Altered white matter microstructure in lupus patients : A diffusion tensor imaging study
- Tumour necrosis factor-α/etanercept complexes in serum predict long-term efficacy of etanercept treatment in seronegative rheumatoid arthritis
- A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts
- White matter lesions and brain atrophy in systemic lupus erythematosus patients : correlation to cognitive dysfunction in a cohort of systemic lupus erythematosus patients using different definition models for neuropsychiatric systemic lupus erythematosus
- Functional Connectivity Changes in Systemic Lupus Erythematosus : A Resting-State Study
- 2017
- Differences in body structure and function between patients with systemic lupus erythematosus and healthy individuals, with particular reference to joint hypermobility
- Comment on : Decreased platelet size is associated with platelet activation and anti-phospholipid syndrome in systemic lupus erythematosus: Reply
- Smoking and pre-existing organ damage reduce the efficacy of belimumab in systemic lupus erythematosus
- Pro-inflammatory S100 proteins are associated with glomerulonephritis and anti-dsDNA antibodies in systemic lupus erythematosus
- Systemic lupus erythematosus : Still a challenge for physicians
- Plasma C4d as marker for lupus nephritis in systemic lupus erythematosus
- Role of interferons in SLE
- A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus
- Deciphering systemic lupus erythematosus-associated serum biomarkers reflecting apoptosis and disease activity
- Stress-induced release of the S100A8/A9 alarmin is elevated in coronary artery disease patients with impaired cortisol response
- Endothelial dysfunction is associated with activation of the type I interferon system and platelets in systemic lupus erythematosus
- Treatment with belimumab in SLE does not alter antobody response to 13-valent pneumococcal vaccine
- Treatment with belimumab in systemic lupus erythematosus does not impair antibody response to 13-valent pneumococcal conjugate vaccine.
- Novel risk genes for systemic lupus erythematosus predicted by random forest classification
- Decreased platelet size is associated with platelet activation and anti-phospholipid syndrome in systemic lupus erythematosus
- 2016
- Variations in the epidemiology of systemic lupus erythematosus in southern Sweden.
- Circulating complexes between tumour necrosis factor-alpha and etanercept predict long-term efficacy of etanercept in juvenile idiopathic arthritis.
- The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation.
- Blood-borne phagocytes internalize urate microaggregates and prevent intravascular NETosis by urate crystals
- The assessment of serum-mediated phagocytosis of necrotic material by polymorphonuclear leukocytes to diagnose and predict the clinical features of systemic lupus erythematosus: an observational longitudinal study
- Platelet-derived S100A8/A9 and cardiovascular disease in systemic lupus erythematosus.
- Impaired phagocytosis and reactive oxygen species production in phagocytes is associated with systemic vasculitis
- Direct and indirect costs for systemic lupus erythematosus in Sweden. A nationwide health economic study based on five defined cohorts.
- 2015
- A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources.
- A novel mechanism for NETosis provides antimicrobial defense at the oral mucosa.
- Total cost and cost predictors in systemic lupus erythematosus - 8-years follow-up of a Swedish inception cohort.
- Type I interferon-mediated skewing of the serotonin synthesis is associated with severe disease in systemic lupus erythematosus.
- Incidence and disease severity of anti-neutrophil cytoplasmic antibody-associated nephritis are higher than in lupus nephritis in Sweden.
- 2014
- Serum from patients with systemic vasculitis induces alternatively activated macrophage M2c polarization.
- Platelet activation and anti-phospholipid antibodies collaborate in the activation of the complement system on platelets in systemic lupus erythematosus.
- Plasma levels of galectin-3-binding protein reflect type I interferon activity and are increased in patients with systemic lupus erythematosus.
- Multiplexing of miniaturized planar antibody arrays for serum protein profiling - a biomarker discovery in SLE nephritis.
- Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus
- The complement system in systemic lupus erythematosus: an update.
- Clinical phenotype associations with various types of anti-dsDNA antibodies in patients with recent onset of rheumatic symptoms. Results from a multicentre observational study.
- Pathogenic Mechanisms in Lupus Nephritis: Nucleosomes Bind Aberrant Laminin β1 With High Affinity and Colocalize in the Electron-Dense Deposits.
- Belimumab in systemic lupus erythematosus -- what can be learned from longterm observational studies?
- 2013
- C-reactive protein, immunoglobulin G and complement co-localize in renal immune deposits of proliferative lupus nephritis
- Increased serum levels of S100A8/A9 and S100A12 are associated with cardiovascular disease in patients with inactive systemic lupus erythematosus.
- Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility
- An observational study of outcome in SLE patients with biopsy-verified glomerulonephritis between 1986 and 2004 in a defined area of Southern Sweden: the clinical utility of the ACR renal response criteria and predictors for renal outcome.
- Phase I, Randomized, Double-Blind, Placebo-Controlled, Multiple Intravenous, Dose-Ascending Study of Sirukumab in Cutaneous or Systemic Lupus Erythematosus
- Association of STAT4 Polymorphism with Severe Renal Insufficiency in Lupus Nephritis.
- HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus
- Low diagnostic and predictive value of anti-dsDNA antibodies in unselected patients with recent onset of rheumatic symptoms: results from a long-term follow-up Scandinavian multicentre study.
- Coronary Heart Disease in Systemic Lupus Erythematosus Is Associated With Interferon Regulatory Factor-8 Gene Variants
- Circulating MicroRNA Expression Profiles Associated With Systemic Lupus Erythematosus
- Increased serum type I interferon activity in early systemic sclerosis patients is associated with antibodies against Sjögren's syndrome antigens and nuclear ribonucleoprotein antigens.
- Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations
- 2012
- Pharmacokinetics, tolerability, and preliminary efficacy of paquinimod (ABR-215757), a new quinoline-3-carboxamide derivative: Studies in lupus-prone mice and a multicenter, randomized, double-blind, placebo-controlled, repeat-dose, dose-ranging study in patients with systemic lupus erythematosus
- IgG glycan hydrolysis by EndoS diminishes the pro-inflammatory properties of immune complexes from patients with SLE - a possible new treatment?
- Vaccination against encapsulated bacteria in hereditary C2 deficiency results in antibody response and opsonization due to antibody-dependent complement activation.
- Combination of Autoantibodies Against Different Histone Proteins Influences Complement-dependent Phagocytosis of Necrotic Cell Material by Polymorphonuclear Leukocytes in Systemic Lupus Erythematosus.
- IgG glycan hydrolysis by endoglycosidase S diminishes the proinflammatory properties of immune complexes from patients with systemic lupus erythematosus: A possible new treatment?
- Clinical manifestations and anti-phospholipid antibodies in 712 patients with systemic lupus erythematosus: evaluation of two diagnostic assays.
- Decreased Neutrophil Apoptosis in Quiescent ANCA-Associated Systemic Vasculitis.
- Increased C1q, C4 and C3 deposition on platelets in patients with systemic lupus erythematosus - a possible link to venous thrombosis?
- Neutrophil Extracellular Traps That Are Not Degraded in Systemic Lupus Erythematosus Activate Complement Exacerbating the Disease.
- Serum COMP-C3b complexes in rheumatic diseases and relation to anti-TNF-alpha treatment
- 2011
- A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE
- Association of the Charlson Comorbidity Index With Mortality in Systemic Lupus Erythematosus
- Protein synthesis of the pro-inflammatory S100A8/A9 complex in plasmacytoid dendritic cells and cell surface S100A8/A9 on leukocyte subpopulations in systemic lupus erythematosus
- Increased plasma levels of the soluble Mer tyrosine kinase receptor in systemic lupus erythematosus relate to disease activity and nephritis
- Serum protein profiling of systemic lupus erythematosus and systemic sclerosis using recombinant antibody microarrays.
- Circulating NET remnants in ANCA-AASV
- Plasma concentrations of Gas6 and sAxl correlate with disease activity in systemic lupus erythematosus.
- Systemic lupus erythematosus and cardiac risk factors: medical record documentation and patient adherence
- Mutations in genes encoding complement inhibitors CD46 and CFH affect the age at nephritis onset in patients with systemic lupus erythematosus
- 2010
- Elevated neutrophil membrane expression of proteinase 3 is dependent upon CD177 expression.
- A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus
- Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: up-regulation of the type I interferon system is strongly associated with vascular disease.
- 2009
- C1q Inhibits Immune Complex-Induced Interferon-alpha Production in Plasmacytoid Dendritic Cells A Novel Link Between C1q Deficiency and Systemic Lupus Erythematosus Pathogenesis
- Studies of mechanisms underlying the prolonged neutrophil survival in ANCA-associated systemic vasculitis
- C1q inhibits immune complex induced IFN-alpha production in plasmacytoid dendritic cells-A novel link between C1q deficiency and SLE pathogenesis
- A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
- A comparison between biopsy-proven Lupus and ANCA-associated nephritis within a defined geographical area in southern Sweden
- Limitations of Antinuclear Antibody Tests (HEp-2) Are Overcome with the Autoimmune Target Test (IT-1) in Systemic Lupus Erythematosus Reply
- 2008
- Presence of IgG-CD4 complexes in the circulation
- Gene expression profiling for the identification of G-protein coupled receptors in human platelets
- Effect on interferon-inducible gene expression signature by ABR215757, a new drug in development for SLE
- Progressive multifocal leukoencephalopathy - the importance of early diagnosis illustrated in four cases.
- SLE serum induces classical caspase-dependent apoptosis independent of death receptors
- Complement classical pathway components are all important in clearance of apoptotic cells
- Hand function and performance of daily activities in systemic lupus erythematosus.
- Abnormal Antinuclear Antibody Titers Are Less Common Than Generally Assumed in Established Cases of Systemic Lupus Erythematosus.
- Role of C1q in regulation of IFN-alpha production
- Improved Lupus Outcome. We Are Doing a Good Job, But Could We Do Better?
- Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX
- 2007
- Antibody microarray-based serum protein profiling of system lupus erythematosus and systemic sclerosis
- Genetically determined mannan-binding lectin deficiency is of minor importance in determining susceptibility to severe infections and vascular organ damage in systemic lupus erythematosus.
- C4b-binding protein and factor h compensate for the loss of membrane-bound complement inhibitors to protect apoptotic cells against excessive complement attack
- Use of Serum or Buffer-Changed EDTA-Plasma in a Rapid, Inexpensive, and Easy-To-Perform Hemolytic Complement Assay for Differential Diagnosis of Systemic Lupus Erythematosus and Monitoring of Patients with the Disease
- Rheumatological manifestations, organ damage and autoimmunity in hereditary C2 deficiency.
- Gene-environment interactions in the aetiology of systemic lupus erythematosus
- Association between SLE nephritis and polymorphic variants of the CRP and Fc gamma RIIIa genes
- Complement deficiencies and systemic lupus erythematosus
- Adherence with advice and prescriptions in SLE is mostly good, but better follow up is needed: A study with a questionnaire.
- 2005
- Anti-CRP autoantibody levels correlate with disease activity in systemic lupus erythematosus
- 2004
- Analysis of HLA DR, HLA DQ, C4A, FcgammaRIIa, FcgammaRIIIa, MBL, and IL-1Ra allelic variants in Caucasian systemic lupus erythematosus patients suggests an effect of the combined FcgammaRIIa R/R and IL-1Ra 2/2 genotypes on disease susceptibility.
- P2 receptor mRNA expression profiles in human lymphocytes, monocytes and CD34+ stem and progenitor cells.
- Transcriptional down-regulation of the platelet ADP receptor P2Y(12) and clusterin in patients with systemic lupus erythematosus.
- Induction of apoptosis in monocytes and lymphocytes by serum from patients with systemic lupus erythematosus - an additional mechanism to increased autoantigen load?
- Thrombotic disease in systemic lupus erythematosus is associated with a maintained systemic platelet activation
- Reduced anti-TNFalpha autoantibody levels coincide with flare in systemic lupus erythematosus
- Serum levels of autoantibodies against monomeric C-reactive protein are correlated with disease activity in systemic lupus erythematosus
- 2003
- The heterogeneity of neuropsychiatric systemic lupus erythematosus is reflected in lack of association with cerebrospinal fluid cytokine profiles.
- 2002
- On the etiology and pathogenesis of systemic lupus erythematosus with special reference to environmental factors
- High predictive value of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology damage index for survival in systemic lupus erythematosus.
- Outcome of neuropsychiatric systemic lupus erythematosus within a defined Swedish population: increased morbidity but low mortality.
- 2001
- Increased level of soluble HLA class I antigens in systemic lupus erythematosus: correlation with anti-DNA antibodies and leukopenia
- Malignancies during follow-up in an epidemiologically defined systemic lupus erythematosus inception cohort in southern Sweden
- 2000
- Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies
- No serological indications that systemic lupus erythematosus is linked with exposure to human parvovirus B19
- 1999
- DNA levels in circulating immune complexes decrease at severe SLE flares-correlation with complement component C1q
- 1994
- Increased antiretroviral antibody reactivity in sera from a defined population of patients with systemic lupus erythematosus. Correlation with autoantibodies and clinical manifestations