Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Correlation between Stated and Measured Concentrations of Acrylate and Methacrylate Allergens in Patch-Test Preparations

Goon, Anthony LU ; Bruze, Magnus LU ; Zimerson, Erik LU ; Sörensen, Östen LU ; Goh, Chee-Leok ; Koh, David Soo-Quee and Isaksson, Marléne LU (2011) In Dermatitis 22(1). p.27-32
Abstract
Background: Contact allergy to acrylates and methacrylates is not uncommon. The allergy is confirmed by patch-testing patients with commercial patch-test preparations. Objective: To investigate acrylate and methacrylate allergens used for patch testing in nine different dermatology departments from Europe, America, Asia, and Australia. Methods: The acrylate and methacrylate (methyl methacrylate, 2-hydroxypropyl acrylate, 2-hydroxyethyl methacrylate, ethylene glycol dimethacrylate, and triethylene glycol diacrylate) allergen samples were analyzed with high-performance liquid chromatography to measure the allergen content. Results: Variation in measured versus stated concentrations was seen in these samples. The ratio of measured to stated... (More)
Background: Contact allergy to acrylates and methacrylates is not uncommon. The allergy is confirmed by patch-testing patients with commercial patch-test preparations. Objective: To investigate acrylate and methacrylate allergens used for patch testing in nine different dermatology departments from Europe, America, Asia, and Australia. Methods: The acrylate and methacrylate (methyl methacrylate, 2-hydroxypropyl acrylate, 2-hydroxyethyl methacrylate, ethylene glycol dimethacrylate, and triethylene glycol diacrylate) allergen samples were analyzed with high-performance liquid chromatography to measure the allergen content. Results: Variation in measured versus stated concentrations was seen in these samples. The ratio of measured to stated concentrations ranged from 0.11 to 1.1. Only 22 (63%) of 35 samples were within the arbitrary acceptable limits of 80 to 120% of the stated concentrations. Conclusion: The results may have implications for individual diagnosis and prevention and when test results from various centers are compared. (Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Dermatitis
volume
22
issue
1
pages
27 - 32
publisher
Lippincott Williams & Wilkins
external identifiers
  • wos:000290468700004
  • scopus:79951483001
ISSN
1710-3568
DOI
10.2310/6620.2011.10083
language
English
LU publication?
yes
id
eff34333-5cd7-4c67-9921-2f1af5868f76 (old id 1986897)
date added to LUP
2016-04-01 09:57:40
date last changed
2022-04-19 21:20:51
@article{eff34333-5cd7-4c67-9921-2f1af5868f76,
  abstract     = {{Background: Contact allergy to acrylates and methacrylates is not uncommon. The allergy is confirmed by patch-testing patients with commercial patch-test preparations. Objective: To investigate acrylate and methacrylate allergens used for patch testing in nine different dermatology departments from Europe, America, Asia, and Australia. Methods: The acrylate and methacrylate (methyl methacrylate, 2-hydroxypropyl acrylate, 2-hydroxyethyl methacrylate, ethylene glycol dimethacrylate, and triethylene glycol diacrylate) allergen samples were analyzed with high-performance liquid chromatography to measure the allergen content. Results: Variation in measured versus stated concentrations was seen in these samples. The ratio of measured to stated concentrations ranged from 0.11 to 1.1. Only 22 (63%) of 35 samples were within the arbitrary acceptable limits of 80 to 120% of the stated concentrations. Conclusion: The results may have implications for individual diagnosis and prevention and when test results from various centers are compared.}},
  author       = {{Goon, Anthony and Bruze, Magnus and Zimerson, Erik and Sörensen, Östen and Goh, Chee-Leok and Koh, David Soo-Quee and Isaksson, Marléne}},
  issn         = {{1710-3568}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{27--32}},
  publisher    = {{Lippincott Williams & Wilkins}},
  series       = {{Dermatitis}},
  title        = {{Correlation between Stated and Measured Concentrations of Acrylate and Methacrylate Allergens in Patch-Test Preparations}},
  url          = {{http://dx.doi.org/10.2310/6620.2011.10083}},
  doi          = {{10.2310/6620.2011.10083}},
  volume       = {{22}},
  year         = {{2011}},
}