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- 2019
- Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality
- CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I
- 2018
-
Modulation of Protein-Interaction States through the Cell Cycle
Dai, Lingyun ; Zhao, Tianyun ; Bisteau, Xavier ; Sun, Wendi ; Prabhu, Nayana ; Lim, Yan Ting ; Sobota, Radoslaw M ; Kaldis, Philipp LU
and
Nordlund, Pär
(2018)
In Cell
173(6).
p.1481-1494
Mark
- Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells
- 2017
-
Loss of cyclin-dependent kinase 2 in the pancreas links primary β-cell dysfunction to progressive depletion of β-cell mass and diabetes
Kim, So Yoon ; Lee, Ji Hyeon ; Merrins, Matthew J. ; Gavrilova, Oksana ; Bisteau, Xavier ; Kaldis, Philipp LU
;
Satin, Leslie S.
and
Rane, Sushil G.
(2017)
In Journal of Biological Chemistry
292(9).
p.3841-3853
Mark
- CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays
- 2016
-
Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint
Diril, M. Kasim ; Bisteau, Xavier ; Kitagawa, Mayumi ; Caldez, Matias J. ; Wee, Sheena ; Gunaratne, Jayantha ; Lee, Sang Hyun and Kaldis, Philipp LU
(2016)
In PLoS Genetics
12(9).
p.1-26
Mark
- Cyclin A2 regulates erythrocyte morphology and numbers
- Cdk2 catalytic activity is essential for meiotic cell division in vivo
- 2015
-
Hematopoiesis specific loss of Cdk2 and Cdk4 results in increased erythrocyte size and delayed platelet recovery following stress
Jayapal, Senthil Raja ; Wang, Chelsia Qiuxia ; Bisteau, Xavier ; Caldez, Matias J. ; Lim, Shuhui ; Tergaonkar, Vinay ; Osato, Motomi and Kaldis, Philipp LU
(2015)
In Haematologica
100(4).
p.431-438
Mark
-
A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity
Heijink, Anne Margriet ; Blomen, Vincent A. ; Bisteau, Xavier ; Degener, Fabian ; Matsushita, Felipe Yu ; Kaldis, Philipp LU
;
Foijer, Floris
and
Van Vugt, Marcel A.T.M.
(2015)
In Proceedings of the National Academy of Sciences of the United States of America
112(49).
p.15160-15165
Mark
- 2014
- Spy1/SpeedyA accelerates neuroblastoma
- The complex relationship between liver cancer and the cell cycle : A story of multiple regulations