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- 2020
- Spatial patterns of tau deposition are associated with amyloid, ApoE, sex, and cognitive decline in older adults
- Relevance of biomarkers across different neurodegenerative
- Perspectives in fluid biomarkers in neurodegeneration from the 2019 biomarkers in neurodegenerative diseases course - A joint PhD student course at University College London and University of Gothenburg
- The properties of α-synuclein secondary nuclei are dominated by the solution conditions rather than the seed fibril strain
- Why Is Amyloid-β PET Requested After Performing CSF Biomarkers?
- Secondary Nucleation in Amyloid Formation
- Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein
- Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors
- The role of fibril structure and surface hydrophobicity in secondary nucleation of amyloid fibrils
- Kinetic diversity of amyloid oligomers
- Amyloid-specific extraction using organic solvents
- Stage-specific links between plasma neurofilament light and imaging biomarkers of Alzheimer's disease
- 2019
-
APP depletion alters selective pre- and post-synaptic proteins
Martinsson, Isak LU ; Capetillo-Zarate, Estibaliz ; Faideau, Mathilde LU ; Willén, Katarina LU ; Esteras, Noemi ; Frykman, Susanne ; Tjernberg, Lars O. and Gouras, Gunnar K. LU
(2019)
In Molecular and Cellular Neuroscience
95.
p.86-95
Mark
- Assessment of the appropriate use criteria for amyloid PET in an unselected memory clinic cohort : The ABIDE project
- Discordant amyloid-β PET and CSF biomarkers and its clinical consequences
-
A new perspective for advanced positron emission tomography–based molecular imaging in neurodegenerative proteinopathies
Perani, Daniela ; Iaccarino, Leonardo ; Lammertsma, Adriaan A. ; Windhorst, Albert D. ; Edison, Paul ; Boellaard, Ronald ; Hansson, Oskar LU
; Nordberg, Agneta
and Jacobs, Andreas H.
(2019)
In Alzheimer's and Dementia
15(8).
p.1081-1103
Mark
-
Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort
Kim, Min ; Ali, Ashfaq LU
and Legido-Quigley, Cristina
(2019)
In Alzheimer's and Dementia
15(6).
p.817-827
Mark
- 2018
- Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease
- The National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease : Perspectives from the Research Roundtable
-
Prion-like seeding and nucleation of intracellular amyloid-β
Olsson, Tomas T. LU ; Klementieva, Oxana LU
and Gouras, Gunnar K.
LU
(2018)
In Neurobiology of Disease
113.
p.1-10
Mark
-
Amyloid pathology in the progression to mild cognitive impairment
Insel, Philip S. LU ; Hansson, Oskar LU
; Mackin, R. Scott
; Weiner, Michael
and Mattsson, Niklas
LU
(2018)
In Neurobiology of Aging
64.
p.76-84
Mark
- Fluid Biomarkers in Alzheimer’s Disease and Frontotemporal Dementia
- Preparation and culturing of human primary vascular cells
- On the role of sidechain size and charge in the aggregation of Aβ42 with familial mutations
-
Amyloid network topology characterizes the progression of Alzheimer's disease during the predementia stages
Pereira, Joana B. ; Strandberg, Tor Olof ; Palmqvist, Sebastian LU
; Volpe, Giovanni
; Van Westen, Danielle
LU
; Westman, Eric
and Hansson, Oskar
LU
(2018)
In Cerebral Cortex
28(1).
p.340-349
Mark
- Sex-specific genetic predictors of Alzheimer’s disease biomarkers
-
Abnormal structural brain connectome in individuals with preclinical Alzheimer's disease
Pereira, Joana B. LU ; Van Westen, Danielle LU
; Stomrud, Erik
LU
; Strandberg, Tor Olof
; Volpe, Giovanni
; Westman, Eric
and Hansson, Oskar
LU
(2018)
In Cerebral Cortex
28(10).
p.3638-3649
Mark
- 2017
-
Increased blood-brain barrier permeability is associated with dementia and diabetes but not amyloid pathology or APOE genotype
Janelidze, Shorena LU ; Hertze, Joakim LU ; Nägga, Katarina LU ; Nilsson, Karin ; Nilsson, Christer LU ; Wennström, Malin LU ; van Westen, Danielle LU
; Blennow, Kaj
LU
; Zetterberg, Henrik
LU
and Hansson, Oskar
LU
(2017)
In Neurobiology of Aging
51.
p.104-112
Mark
-
The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation
Kulak, Klaudia LU ; Westermark, Gunilla T. ; Papac-Milicevic, Nikolina ; Renström, Erik LU ; Blom, Anna M. LU
and King, Ben C.
LU
(2017)
In Diabetologia
60(8).
p.1522-1533
Mark
- Involvement of endosomal and synaptic Aβ in models of Alzheimer's disease.
- Cerebrovascular and amyloid pathology in predementia stages : The relationship with neurodegeneration and cognitive decline
-
Recommendations for cerebrospinal fluid collection for the analysis by ELISA of neurogranin trunc P75, α-synuclein, and total tau in combination with Aβ(1-42)/Aβ(1-40)
Vanderstichele, Hugo ; Demeyer, Leentje ; Janelidze, Shorena LU ; Coart, Els ; Stoops, Erik ; Mauroo, Kimberley ; Herbst, Victor ; François, Cindy and Hansson, Oskar LU
(2017)
In Alzheimer's Research and Therapy
9(1).
Mark
- Ponezumab in mild-to-moderate Alzheimer's disease : Randomized phase II PET-PIB study
- 2016
- Analysis of the length distribution of amyloid fibrils by centrifugal sedimentation
-
Assessing risk for preclinical β-amyloid pathology with APOE, cognitive, and demographic information
Insel, Philip S. LU ; Palmqvist, Sebastian LU
; Mackin, R. Scott
; Nosheny, Rachel L.
; Hansson, Oskar
LU
; Weiner, Michael W.
and Mattsson, Niklas
LU
(2016)
In Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
4.
p.76-84
Mark
-
Optimized Standard Operating Procedures for the Analysis of Cerebrospinal Fluid Aβ42 and the Ratios of Aβ Isoforms Using Low Protein Binding Tubes
Vanderstichele, Hugo Marcel Johan ; Janelidze, Shorena LU ; Demeyer, Leentje ; Coart, Els ; Stoops, Erik ; Herbst, Victor ; Mauroo, Kimberley ; Brix, Britta and Hansson, Oskar LU
(2016)
In Journal of Alzheimer's Disease
53(3).
p.1121-1132
Mark
- 2014
- The chaperone domain BRICHOS prevents CNS toxicity of amyloid-beta peptide in Drosophila melanogaster
-
Fertility Defects in Mice Expressing the L68Q Variant of Human Cystatin C A ROLE FOR AMYLOID IN MALE INFERTILITY
Whelly, Sandra ; Serobian, Gaiane ; Borchardt, Clinton ; Powell, Jonathan ; Johnson, Seethal ; Håkansson, Katarina LU ; Lindström, Veronica LU
; Abrahamson, Magnus
LU
; Grubb, Anders
LU
and Cornwall, Gail A.
(2014)
In Journal of Biological Chemistry
289(11).
p.7718-7729
Mark
- Anti-amyloid compounds inhibit α-synuclein aggregation induced by protein misfolding cyclic amplification (PMCA)
-
Conformational and aggregation properties of the 1-93 fragment of apolipoprotein A-I
Petrlova, Jitka LU ; Bhattacherjee, Arnab LU ; Boomsma, Wouter LU ; Wallin, Stefan LU ; Lagerstedt, Jens O LU and Irbäck, Anders LU
(2014)
In Protein Science
23(11).
p.71-1559
Mark
- 2013
- Molecular Mechanisms in Amyloid Disorders. Novel Treatment Options in Hereditary Cystatin C Amyloid Angiopathy.
-
Fluid biomarkers in Alzheimer's disease - current concepts
Rosen, Christoffer ; Hansson, Oskar LU
; Blennow, Kaj
and Zetterberg, Henrik
(2013)
In Molecular Neurodegeneration
8.
Mark
- A beta 1-15/16 as a Potential Diagnostic Marker in Neurodegenerative Diseases
- 2012
-
Monte Carlo studies of protein aggregation
Jonsson, Sigurdur LU ; Staneva, Iskra LU ; Mohanty, Sandipan LU and Irbäck, Anders LU
(2012)
25th Workshop on Computer Simulation Studies in Condensed Matter Physics
34.
p.49-54
Mark
-
Distinct phases of free α-synuclein - A Monte Carlo study.
Jonsson, Sigurdur LU ; Mohanty, Sandipan and Irbäck, Anders LU
(2012)
In Proteins
80(9).
p.2169-2177
Mark
-
Critical role of intraneuronal A beta in Alzheimer's disease: Technical challenges in studying intracellular A beta
Gouras, Gunnar LU
; Willén, Katarina
LU
and Tampellini, Davide
LU
(2012)
In Life Sciences
91(23-24).
p.1153-1158
Mark
-
Intraneuronal A beta Accumulation, Amyloid Plaques, and Synapse Pathology in Alzheimer's Disease
Capetillo-Zarate, Estibaliz ; Gracia, Luis ; Tampellini, Davide LU and Gouras, Gunnar LU
(2012)
In Neurodegenerative Diseases
10(1-4).
p.56-59
Mark
- 2011
-
Monte Carlo Study of the Formation and Conformational Properties of Dimers of Aβ42 Variants.
Mitternacht, Simon LU ; Staneva, Iskra LU ; Härd, Torleif and Irbäck, Anders LU
(2011)
In Journal of Molecular Biology
410(2).
p.357-367
Mark
-
Cerebrospinal Fluid Biomarkers for Alzheimer's Disease: Diagnostic Performance in a Homogeneous Mono-Center Population
Johansson, Per LU ; Mattsson, Niklas ; Hansson, Oskar LU
; Wallin, Anders
; Johansson, Jan-Ove
; Andreasson, Ulf
; Zetterberg, Henrik
; Blennow, Kaj
LU
and Svensson, Johan
(2011)
In Journal of Alzheimer's Disease
24(3).
p.537-546
Mark
- 2010
- Amyloid beta-Protein Aggregation Produces Highly Reproducible Kinetic Data and Occurs by a Two-Phase Process
- Crystal structure of human cystatin C stabilized against amyloid formation
- Dual Effect of Amino Modified Polystyrene Nanoparticles on Amyloid beta Protein Fibrillation
-
Converging Pathways of Chromogranin and Amyloid Metabolism in the Brain
Mattsson, Niklas ; Johansson, Per LU ; Hansson, Oskar LU
; Wallin, Anders
; Johansson, Jan-Ove
; Andreasson, Ulf
; Andersen, Oluf
; Haghighi, Sara
; Olsson, Maria
and Stridsberg, Mats
, et al.
(2010)
In Journal of Alzheimer's Disease
20(4).
p.1039-1048
Mark
-
Synapses, synaptic activity and intraneuronal Aβ in Alzheimer's disease
Tampellini, Davide LU and Gouras, Gunnar K. LU
(2010)
In Frontiers in Aging Neuroscience
2(MAY).
Mark
-
Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer's disease
Gouras, Gunnar K. LU
; Tampellini, Davide
LU
; Takahashi, Reisuke H.
and Capetillo-Zarate, Estibaliz
(2010)
In Acta Neuropathologica
119(5).
p.523-541
Mark
-
Co-occurrence of Alzheimer's disease β-amyloid and tau pathologies at synapses
Takahashi, Reisuke H. ; Capetillo-Zarate, Estibaliz ; Lin, Michael T. ; Milner, Teresa A. and Gouras, Gunnar K. LU
(2010)
In Neurobiology of Aging
31(7).
p.1145-1152
Mark
- 2009
- A facile method for expression and purification of the Alzheimer's disease-associated amyloid beta-peptide
- International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders
-
Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease
Dumont, Magali ; Wille, Elizabeth ; Calingasan, Noel Y. ; Tampellini, Davide LU ; Williams, Charlotte ; Gouras, Gunnar K. LU
; Liby, Karen
; Sporn, Michael
; Flint Beal, M.
and Lin, Michael T.
(2009)
In Journal of Neurochemistry
109(2).
p.502-512
Mark
- Dementia
- Immunotherapy for Alzheimer disease
- 2007
- Nucleation of protein fibrillation by nanoparticles
- 2006
- Lactadherin binds to elastin - a starting point for medin amyloid formation?
- 2005
- 3D domain-swapped human cystatin c with amyloidlike intermolecular beta-sheets
-
Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses
Almeida, Claudia G. ; Tampellini, Davide LU ; Takahashi, Reisuke H. ; Greengard, Paul ; Lin, Michael T. ; Snyder, Eric M. and Gouras, Gunnar K. LU
(2005)
In Neurobiology of Disease
20(2).
p.187-198
Mark
-
Intraneuronal Aβ accumulation and origin of plaques in Alzheimer's disease
Gouras, Gunnar K. LU
; Almeida, Claudia G.
and Takahashi, Reisuke H.
(2005)
In Neurobiology of Aging
26(9).
p.1235-1244
Mark
-
Intraneuronal β-amyloid expression downregulates the Akt survival pathway and blunts the stress response
Magrané, Jordi ; Rosen, Kenneth M. ; Smith, Roy C. ; Walsh, Kenneth ; Gouras, Gunnar K. LU
and Querfurth, Henry W.
(2005)
In Journal of Neuroscience
25(47).
p.10960-10969
Mark
- 2004
- Islet amyloid polypeptide-induced membrane leakage involves uptake of lipids by forming amyloid fibers
-
Oligomerization of Alzheimer's β-Amyloid within Processes and Synapses of Cultured Neurons and Brain
Takahashi, Reisuke H. ; Almeida, Claudia G. ; Kearney, Patrick F. ; Yu, Fangmin ; Lin, Michael T. ; Milner, Teresa A. and Gouras, Gunnar K. LU
(2004)
In Journal of Neuroscience
24(14).
p.3592-3599
Mark
- 2001
- Diffuse primary plasmacytoma of the lung
- 2000
- L68Q cystatin C: Expression, cellular transport and turnover of the cystatin C variant forming amyloid in patients with Hereditary Cystatin C Amyloid Angiopaty (HCCAA)
- 1997
-
Islet amyloid polypeptide and calcitonin gene-related peptide expression are upregulated in lumbar dorsal root ganglia after unilateral adjuvant-induced inflammation in the rat paw
Mulder, H LU
; Zhang, Y
LU
; Danielsen, N
LU
and Sundler, F
LU
(1997)
In Molecular Brain Research
50(1-2).
p.35-127
Mark
-
Islet amyloid polypeptide and calcitonin gene-related peptide expression are down-regulated in dorsal root ganglia upon sciatic nerve transection
Mulder, H LU
; Zhang, Y
LU
; Danielsen, N
LU
and Sundler, F
LU
(1997)
In Molecular Brain Research
47(1-2).
p.30-322
Mark
- 1996
- Increased plasma levels of islet amyloid polypeptide in patients with primary hyperparathyroidism