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- 2019
- Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies
- How is alpha-synuclein cleared from the cell?
- 2018
- In vivo quantification of glial activation in minipigs overexpressing human α-synuclein
- α-Synuclein Fibril Formation and the Effects of Lipid Membranes
- Heterogeneity in α-synuclein subtypes and their expression in cortical brain tissue lysates from Lewy body diseases and Alzheimer's disease
- 2017
- Human astrocytes transfer aggregated alpha-synuclein via tunneling nanotubes
- 2016
- Pathogenic effects of alpha-synuclein: modifications and toxicity
- Longitudinal changes in CSF alpha-synuclein species reflect Parkinson's disease progression
- A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synuclein
- 2015
-
A Genetic Mouse Model of Parkinson's Disease Shows Involuntary Movements and Increased Postsynaptic Sensitivity to Apomorphine
Brehm, N. ; Bez, Francesco LU ; Carlsson, T. ; Kern, B. ; Gispert, S. ; Auburger, G. and Cenci Nilsson, Angela LU
(2015)
In Molecular Neurobiology
52(3).
p.1152-1164
Mark
- Fluorescent Probes and Protein Misfolding: Methods and Applications
- Toll-like receptor expression in the blood and brain of patients and a mouse model of Parkinson's disease
- 2014
-
A porous silicon immunoassay platform for fluorometric determination of alpha-synuclein in human cerebrospinal fluid
Lee, Sangwook ; Silajdzic, Edina LU ; Yang, Hon ; Björkqvist, Maria LU ; Kim, Soyon ; Jeong, Ok Chan ; Hansson, Oskar LU
and
Laurell, Thomas
LU
(2014)
In Mikrochimica Acta
181(9-10).
p.1143-1149
Mark
- Alpha-Synuclein Repeat Variants and Survival in Parkinson's Disease
- Protective effect of LRRK2 p.R1398H on risk of Parkinson's disease is independent of MAPT and SNCA variants
- Anti-amyloid compounds inhibit α-synuclein aggregation induced by protein misfolding cyclic amplification (PMCA)
- 2013
- LAMP2A as a therapeutic target in Parkinson disease
-
Ser129D mutant alpha-synuclein induces earlier motor dysfunction while S129A results in distinctive pathology in a rat model of Parkinson's disease
Febbraro, Fabia ; Sahin, Gurdal LU
;
Farran, Aina
;
Soares, Sofia
;
Jensen, Poul H.
;
Kirik, Deniz
LU
and
Romero-Ramos, Marina
(2013)
In Neurobiology of Disease
56.
p.47-58
Mark
- What's to like about the prion-like hypothesis for the spreading of aggregated α-synuclein in Parkinson disease?
- Cholinergic and dopaminergic aspects of dementia in Parkinson's disease: postmortem neuropathological findings and modeling of cognitive dysfunction in rodents
- Animal Models of Parkinson's Disease: Limits and Relevance to Neuroprotection Studies
- Boosting chaperone-mediated autophagy in vivo mitigates alpha-synuclein-induced neurodegeneration
- 2012
- A Pilot Study Examining Associations between DYRK1A and alpha-Synuclein Dementias
- Long-term polarization of microglia upon α-synuclein overexpression in nonhuman primates
- Altered CSF Orexin and α-Synuclein Levels in Dementia Patients.
-
Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons.
Decressac, Mickael LU ; Mattsson, Bengt LU ; Lundblad, Martin LU ; Weikop, P and Björklund, Anders LU
(2012)
In Neurobiology of Disease
45(3).
p.939-953
Mark
- 2011
- Signs of Degeneration in 12-22-Year Old Grafts of Mesencephalic Dopamine Neurons in Patients with Parkinson's Disease
- Heredity in Parkinson's disease. From rare mutations to common genetic risk factors.
-
GDNF fails to exert neuroprotection in a rat {alpha}-synuclein model of Parkinson's disease.
Decressac, Mickael LU ; Ulusoy, Ayse LU ; Mattsson, Bengt LU ; Georgievska, Biljana ; Romero-Ramos, Marina ; Kirik, Deniz LU and Björklund, Anders LU
(2011)
In Brain
134(8).
p.2302-2311
Mark
- A deadly spread: cellular mechanisms of α-synuclein transfer.
- 2010
- Does A "Prion-Like" Mechanism Contribute to the Spreading of Neuropathology in Parkinson's Disease?
-
Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease.
Li, Jia-Yi LU ; Englund, Elisabet LU ; Widner, Håkan LU ; Rehncrona, Stig LU ; Björklund, Anders LU
;
Lindvall, Olle
LU
and
Brundin, Patrik
LU
(2010)
In Movement Disorders
25(8).
p.1091-1096
Mark
- 2009
- Suppression of Map Kinases Inhibits Microglial Activation and Attenuates Neuronal Cell Death Induced by Alpha-Synuclein Protofibrils
- 2008
- The effect of alpha-synuclein knockdown on MPP plus toxicity in models of human neurons
- 2007
-
High dose levodopa therapy is not toxic in multiple system atrophy: Experimental evidence
Stefanova, Nadia ; Kollensperger, Martin ; Hainzer, Monika ; Cenci Nilsson, Angela LU
;
Poewe, Werner
and
Wenning, Gregor Karl
(2007)
In Movement Disorders
27(7).
p.969-973
Mark
- 2002
- Ultrastructure of alpha-synuclein-positive aggregations in U373 astrocytoma and rat primary glial cells