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Robustness of a Biological Indicator Resistance Test Rig

Ahlgren, Matilda and Björklund, Zandra (2006)
Programmes in Helesingborg
Abstract
The objective with the diploma work was to evaluate the robustness of the basic method and test rig used by Tetra Pak for testing the spores (biological indicators) resistance against liquid hydrogen peroxide. Tetra Pak uses liquid hydrogen peroxide as a sterilising agent in their filling machines to achieve an aseptic product. The resistance of the biological indicators is important to know when testing new filling machines and for validation of filling machines. The spore that was used in these tests was Bacillus spores. The assignment was to investigate the influence of different parameters. To compare the different testes a D-value is calculated. D-value is the time required to kill 90% of the viable spore population at a specified... (More)
The objective with the diploma work was to evaluate the robustness of the basic method and test rig used by Tetra Pak for testing the spores (biological indicators) resistance against liquid hydrogen peroxide. Tetra Pak uses liquid hydrogen peroxide as a sterilising agent in their filling machines to achieve an aseptic product. The resistance of the biological indicators is important to know when testing new filling machines and for validation of filling machines. The spore that was used in these tests was Bacillus spores. The assignment was to investigate the influence of different parameters. To compare the different testes a D-value is calculated. D-value is the time required to kill 90% of the viable spore population at a specified temperature. (Less)
Please use this url to cite or link to this publication:
author
Ahlgren, Matilda and Björklund, Zandra
organization
year
type
L1 - 1st term paper (old degree order)
subject
keywords
Robustness, Test Rig, restistance, Biotechnology, Bioteknik
language
English
additional info
Bioteknikprogrammet
id
1325396
date added to LUP
2007-11-06
date last changed
2011-02-22 16:21:05
@misc{1325396,
  abstract     = {The objective with the diploma work was to evaluate the robustness of the basic method and test rig used by Tetra Pak for testing the spores (biological indicators) resistance against liquid hydrogen peroxide. Tetra Pak uses liquid hydrogen peroxide as a sterilising agent in their filling machines to achieve an aseptic product. The resistance of the biological indicators is important to know when testing new filling machines and for validation of filling machines. The spore that was used in these tests was Bacillus spores. The assignment was to investigate the influence of different parameters. To compare the different testes a D-value is calculated. D-value is the time required to kill 90% of the viable spore population at a specified temperature.},
  author       = {Ahlgren, Matilda and Björklund, Zandra},
  keyword      = {Robustness,Test Rig,restistance,Biotechnology,Bioteknik},
  language     = {eng},
  note         = {Student Paper},
  title        = {Robustness of a Biological Indicator Resistance Test Rig},
  year         = {2006},
}