Advanced

Developement and evaluation of methods for comparison of dose distributions in radiotherapy using calculated, synthetic and simulated measured dose distributions

Bengtsson Scherman, Jonas (2009)
Medical Physics Programme
Abstract (Swedish)
ntensity modulated radiation therapy (IMRT) is becoming a more and moreused technique in radiation therapy. The main reason for this is that IMRT treament delivers a more conformal dose to the target together with a better sparing of organs at risk. Quality assurance of the generated IMRT treatment plan is of most importance to ensure that the patient recives the planned dose. Different methods exist for comparison of dose distributions where the gamma evaluation (Low et al. [19]) is the most commonly used. In this thesis different types of evaluation methods have been implemented in an evaluation software.Different types of known errors were introduce in an IMRT-plan (synthetic dose distribution). These synthetic dose distributions were... (More)
ntensity modulated radiation therapy (IMRT) is becoming a more and moreused technique in radiation therapy. The main reason for this is that IMRT treament delivers a more conformal dose to the target together with a better sparing of organs at risk. Quality assurance of the generated IMRT treatment plan is of most importance to ensure that the patient recives the planned dose. Different methods exist for comparison of dose distributions where the gamma evaluation (Low et al. [19]) is the most commonly used. In this thesis different types of evaluation methods have been implemented in an evaluation software.Different types of known errors were introduce in an IMRT-plan (synthetic dose distribution). These synthetic dose distributions were then evaluated with a number of evaulation methods to identify what types of criterion needed to discover the introduced errors. A method for comparison of dose distributions with a statistical approach wasalso introduced and compared with the gamma evaluation method. A gamma criteria of 4% of the maximum dose and 4 mm in positioning is neededto discover all introduced errors. For the developed statistical evaluation method (χ2-test) the standard deviations needed to discover all errors were 1.5% of the maximum dose and 1 mm in positioning. (Less)
Please use this url to cite or link to this publication:
author
Bengtsson Scherman, Jonas
supervisor
organization
year
type
H2 - Master's Degree (Two Years)
subject
keywords
Strålterapi
language
English
id
2157079
date added to LUP
2011-09-13 13:44:42
date last changed
2011-09-13 13:44:42
@misc{2157079,
  abstract     = {ntensity modulated radiation therapy (IMRT) is becoming a more and moreused technique in radiation therapy. The main reason for this is that IMRT treament delivers a more conformal dose to the target together with a better sparing of organs at risk. Quality assurance of the generated IMRT treatment plan is of most importance to ensure that the patient recives the planned dose. Different methods exist for comparison of dose distributions where the gamma evaluation (Low et al. [19]) is the most commonly used. In this thesis different types of evaluation methods have been implemented in an evaluation software.Different types of known errors were introduce in an IMRT-plan (synthetic dose distribution). These synthetic dose distributions were then evaluated with a number of evaulation methods to identify what types of criterion needed to discover the introduced errors. A method for comparison of dose distributions with a statistical approach wasalso introduced and compared with the gamma evaluation method. A gamma criteria of 4% of the maximum dose and 4 mm in positioning is neededto discover all introduced errors. For the developed statistical evaluation method (χ2-test) the standard deviations needed to discover all errors were 1.5% of the maximum dose and 1 mm in positioning.},
  author       = {Bengtsson Scherman, Jonas},
  keyword      = {Strålterapi},
  language     = {eng},
  note         = {Student Paper},
  title        = {Developement and evaluation of methods for comparison of dose distributions in radiotherapy using calculated, synthetic and simulated measured dose distributions},
  year         = {2009},
}