Ultra-sensitive diagnostic method based on Surface Enhanced Raman Spectroscopy on plasmonic beads in suspension
(2013) FYSM31 20131Department of Physics
Solid State Physics
- Abstract (Swedish)
- In this work, surface enhanced Raman spectroscopy (SERS) was combined with dielectrophoresis (DEP) to realize a controllable in situ detection method of enhanced Raman signals from molecules in suspension environment. Polymer beads coated with gold nanoparticles were prepared as SERS ‘hot spot’ substrates. Several DEP electrode designs were evaluated and the stripe electrode succeeded in manipulating the particles to form clusters for creating strong plasmon coupling. We use the finite difference time domain (FDTD) simulation method to evaluate the electric field enhancement for the SERS effect. Enhanced Raman spectrum of 4-mercaptobenzoic acid (4-MBA) and glucose molecule were obtained, and switchable enhancement was achieved for... (More)
- In this work, surface enhanced Raman spectroscopy (SERS) was combined with dielectrophoresis (DEP) to realize a controllable in situ detection method of enhanced Raman signals from molecules in suspension environment. Polymer beads coated with gold nanoparticles were prepared as SERS ‘hot spot’ substrates. Several DEP electrode designs were evaluated and the stripe electrode succeeded in manipulating the particles to form clusters for creating strong plasmon coupling. We use the finite difference time domain (FDTD) simulation method to evaluate the electric field enhancement for the SERS effect. Enhanced Raman spectrum of 4-mercaptobenzoic acid (4-MBA) and glucose molecule were obtained, and switchable enhancement was achieved for functionalized 4-MBA molecules. (Less)
Please use this url to cite or link to this publication:
http://lup.lub.lu.se/student-papers/record/4005098
- author
- Liu, Yujun LU
- supervisor
- organization
- course
- FYSM31 20131
- year
- 2013
- type
- H2 - Master's Degree (Two Years)
- subject
- keywords
- SERS, Raman, DEP, gold nanoparticle, enhancement
- language
- English
- id
- 4005098
- date added to LUP
- 2013-09-09 22:51:45
- date last changed
- 2013-09-09 22:51:45
@misc{4005098, abstract = {{In this work, surface enhanced Raman spectroscopy (SERS) was combined with dielectrophoresis (DEP) to realize a controllable in situ detection method of enhanced Raman signals from molecules in suspension environment. Polymer beads coated with gold nanoparticles were prepared as SERS ‘hot spot’ substrates. Several DEP electrode designs were evaluated and the stripe electrode succeeded in manipulating the particles to form clusters for creating strong plasmon coupling. We use the finite difference time domain (FDTD) simulation method to evaluate the electric field enhancement for the SERS effect. Enhanced Raman spectrum of 4-mercaptobenzoic acid (4-MBA) and glucose molecule were obtained, and switchable enhancement was achieved for functionalized 4-MBA molecules.}}, author = {{Liu, Yujun}}, language = {{eng}}, note = {{Student Paper}}, title = {{Ultra-sensitive diagnostic method based on Surface Enhanced Raman Spectroscopy on plasmonic beads in suspension}}, year = {{2013}}, }