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System Identification applied to Cardiac Activation

Santos, Susana (2001) In MSc Theses
Department of Automatic Control
Abstract
Clarifying the mechanisms maintaining atrial activity during atrial fibrillation (AF), still remains as a relevant topic. The purpose of this master thesis is to apply correlation analysis and system identification methods to study spatial and temporal propagation of atrial activation
along coronary sinus (situated in the posterior left part of the heart, in the groove between left atrium and left ventricle) during paroxysmal atrial fibrillation (PAF) using data recorded catheter from 7 different patients. Furthermore, interatrial mechanisms of impulse conduction can be derived due to the position of coronary sinus. This study demonstrated consistency in electrical activity propagation during atrial fibrillation along coronary sinus in... (More)
Clarifying the mechanisms maintaining atrial activity during atrial fibrillation (AF), still remains as a relevant topic. The purpose of this master thesis is to apply correlation analysis and system identification methods to study spatial and temporal propagation of atrial activation
along coronary sinus (situated in the posterior left part of the heart, in the groove between left atrium and left ventricle) during paroxysmal atrial fibrillation (PAF) using data recorded catheter from 7 different patients. Furthermore, interatrial mechanisms of impulse conduction can be derived due to the position of coronary sinus. This study demonstrated consistency in electrical activity propagation during atrial fibrillation along coronary sinus in five patients out
of six included. Nevertheless, direction and speed of propagation resulted dependent on the patient. The method was tried out during sinus rhythm
(SR) obtaining the expected high consistency in propagation direction and speed which represented an interesting reference point to compare with atrial fibrillation results. Furthermore, linear relation among endocardial electrograms from coronary sinus and time invariant systems have been presented by computing simple linear models based on
least squares method.

Secondly, an impulse response method has been applied to reproduce atrial activations during atrial fibrillation and during sinus rhythm in ten endocardial electrograms from coronary sinus simultaneously. In this case, there is no need of measuring the input which is considered to be an impulse generated in the sinus node. This method was only useful in local prediction of atrial activations but not for prediction in the long term.

Finally, Subspace Model Identification (SMI) methods have been applied to show an input-output relation among signals from inside the heart (endocardial electrograms from coronary sinus) and signals from outside the heart (V1 Surface-ECG). (Less)
Please use this url to cite or link to this publication:
author
Santos, Susana
supervisor
organization
year
type
H3 - Professional qualifications (4 Years - )
subject
publication/series
MSc Theses
report number
TFRT-5666
ISSN
0280-5316
language
English
id
8848246
date added to LUP
2016-03-20 11:23:42
date last changed
2016-03-20 11:23:42
@misc{8848246,
  abstract     = {Clarifying the mechanisms maintaining atrial activity during atrial fibrillation (AF), still remains as a relevant topic. The purpose of this master thesis is to apply correlation analysis and system identification methods to study spatial and temporal propagation of atrial activation
along coronary sinus (situated in the posterior left part of the heart, in the groove between left atrium and left ventricle) during paroxysmal atrial fibrillation (PAF) using data recorded catheter from 7 different patients. Furthermore, interatrial mechanisms of impulse conduction can be derived due to the position of coronary sinus. This study demonstrated consistency in electrical activity propagation during atrial fibrillation along coronary sinus in five patients out
of six included. Nevertheless, direction and speed of propagation resulted dependent on the patient. The method was tried out during sinus rhythm
(SR) obtaining the expected high consistency in propagation direction and speed which represented an interesting reference point to compare with atrial fibrillation results. Furthermore, linear relation among endocardial electrograms from coronary sinus and time invariant systems have been presented by computing simple linear models based on
least squares method.

Secondly, an impulse response method has been applied to reproduce atrial activations during atrial fibrillation and during sinus rhythm in ten endocardial electrograms from coronary sinus simultaneously. In this case, there is no need of measuring the input which is considered to be an impulse generated in the sinus node. This method was only useful in local prediction of atrial activations but not for prediction in the long term.

Finally, Subspace Model Identification (SMI) methods have been applied to show an input-output relation among signals from inside the heart (endocardial electrograms from coronary sinus) and signals from outside the heart (V1 Surface-ECG).},
  author       = {Santos, Susana},
  issn         = {0280-5316},
  language     = {eng},
  note         = {Student Paper},
  series       = {MSc Theses},
  title        = {System Identification applied to Cardiac Activation},
  year         = {2001},
}