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Estimation of Premorbid Intellectual Function in Patients with Mild Cognitive Symptoms using the NART-SWE

Brandström, Maja LU and Lagebrand, Elin LU (2016) PSPT02 20161
Department of Psychology
Abstract
The purpose of this study was to investigate the utility of the National Adult Reading Test - Swedish Version (NART-SWE; Rolstad et al., 2008) in estimating premorbid intelligence for patients with mild cognitive symptoms. Patients with cognitive complaints were recruited from three Memory Clinics in Skåne as a part of the TIDIS project. Initially, a senior neuropsychologist made an estimation of premorbid intelligence based on the results of a synonym test and education. Patients were classified into subgroups depending on the affected cognitive domains. For this thesis, the classification was redone using the NART-SWE based estimation instead, and the two classifications were then compared. To validate the classifications, association... (More)
The purpose of this study was to investigate the utility of the National Adult Reading Test - Swedish Version (NART-SWE; Rolstad et al., 2008) in estimating premorbid intelligence for patients with mild cognitive symptoms. Patients with cognitive complaints were recruited from three Memory Clinics in Skåne as a part of the TIDIS project. Initially, a senior neuropsychologist made an estimation of premorbid intelligence based on the results of a synonym test and education. Patients were classified into subgroups depending on the affected cognitive domains. For this thesis, the classification was redone using the NART-SWE based estimation instead, and the two classifications were then compared. To validate the classifications, association with biomarkers for Alzheimer’s disease was investigated. The results showed that both classifications differentiated between patients with a decline in the memory domain, and patients who did not display objective signs of cognitive decline. A fourth of the patients were reclassified into a different subgroup when using the NART-SWE, however this did not significantly alter the association with the biomarkers. The NART-SWE appears to be closely related to educational attainment, which could explain the small differences between the classifications. Future research should focus on developing more accurate regression equations for the NART-SWE. (Less)
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author
Brandström, Maja LU and Lagebrand, Elin LU
supervisor
organization
course
PSPT02 20161
year
type
H3 - Professional qualifications (4 Years - )
subject
keywords
NART-SWE, MCS, MCI, SCD, premorbid intelligence, dementia, Alzheimer’s disease
language
English
id
8875052
date added to LUP
2016-06-01 13:37:47
date last changed
2016-06-01 13:37:47
@misc{8875052,
  abstract     = {The purpose of this study was to investigate the utility of the National Adult Reading Test - Swedish Version (NART-SWE; Rolstad et al., 2008) in estimating premorbid intelligence for patients with mild cognitive symptoms. Patients with cognitive complaints were recruited from three Memory Clinics in Skåne as a part of the TIDIS project. Initially, a senior neuropsychologist made an estimation of premorbid intelligence based on the results of a synonym test and education. Patients were classified into subgroups depending on the affected cognitive domains. For this thesis, the classification was redone using the NART-SWE based estimation instead, and the two classifications were then compared. To validate the classifications, association with biomarkers for Alzheimer’s disease was investigated. The results showed that both classifications differentiated between patients with a decline in the memory domain, and patients who did not display objective signs of cognitive decline. A fourth of the patients were reclassified into a different subgroup when using the NART-SWE, however this did not significantly alter the association with the biomarkers. The NART-SWE appears to be closely related to educational attainment, which could explain the small differences between the classifications. Future research should focus on developing more accurate regression equations for the NART-SWE.},
  author       = {Brandström, Maja and Lagebrand, Elin},
  keyword      = {NART-SWE,MCS,MCI,SCD,premorbid intelligence,dementia,Alzheimer’s disease},
  language     = {eng},
  note         = {Student Paper},
  title        = {Estimation of Premorbid Intellectual Function in Patients with Mild Cognitive Symptoms using the NART-SWE},
  year         = {2016},
}