Characterization of direct conversion of astroglia into neurons in the hippocampus
(2016) MOBM01 20161Degree Projects in Molecular Biology
- Popular Abstract
- Epilepsy is a disorder in the brain indicated by the occurrence of uncontrollable seizures. The current approaches in treatment of the disease are unsuccessful for 30% of the patients. People suffering from drug resistant epilepsy usually have to remove the part of the brain causing the seizures, which is often the temporal lobe, so novel treatments are urgently needed. Our approach aims at regenerating the population of neurons that are lost during the progression of the disease in the temporal lobe. We target astrocytes, a glia population in the brain that become reactive during epilepsy, to convert them into neurons and thus restore stability in the network of the temporal lobe. This should reduce seizure events.
Please use this url to cite or link to this publication:
http://lup.lub.lu.se/student-papers/record/8894824
- author
- Sathyanarayan, Varsha
- supervisor
- organization
- course
- MOBM01 20161
- year
- 2016
- type
- H2 - Master's Degree (Two Years)
- subject
- language
- English
- id
- 8894824
- date added to LUP
- 2016-11-10 11:15:42
- date last changed
- 2016-11-10 11:15:42
@misc{8894824, author = {{Sathyanarayan, Varsha}}, language = {{eng}}, note = {{Student Paper}}, title = {{Characterization of direct conversion of astroglia into neurons in the hippocampus}}, year = {{2016}}, }