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Characterization of direct conversion of astroglia into neurons in the hippocampus

Sathyanarayan, Varsha (2016) MOBM01 20161
Degree Projects in Molecular Biology
Popular Abstract
Epilepsy is a disorder in the brain indicated by the occurrence of uncontrollable seizures. The current approaches in treatment of the disease are unsuccessful for 30% of the patients. People suffering from drug resistant epilepsy usually have to remove the part of the brain causing the seizures, which is often the temporal lobe, so novel treatments are urgently needed. Our approach aims at regenerating the population of neurons that are lost during the progression of the disease in the temporal lobe. We target astrocytes, a glia population in the brain that become reactive during epilepsy, to convert them into neurons and thus restore stability in the network of the temporal lobe. This should reduce seizure events.
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author
Sathyanarayan, Varsha
supervisor
organization
course
MOBM01 20161
year
type
H2 - Master's Degree (Two Years)
subject
language
English
id
8894824
date added to LUP
2016-11-10 11:15:42
date last changed
2016-11-10 11:15:42
@misc{8894824,
  author       = {Sathyanarayan, Varsha},
  language     = {eng},
  note         = {Student Paper},
  title        = {Characterization of direct conversion of astroglia into neurons in the hippocampus},
  year         = {2016},
}