Defining A Business Model For A Non-Profit Research Core Facility For Nano Delivery Systems Of Nucleic Acid Therapies

Abstract

Nucleic acid therapies represent a groundbreaking approach in modern medicine, capable of potentially curing previously untreatable diseases by modifying gene expression at the DNA or RNA level. Despite their promise, effective delivery of these therapies remains a significant hurdle. Addressing this challenge is the central mission of the soon-to-be-established Chalmers Precision HealthTech Hub. This organization aims to facilitate collaboration between industry and academia, focusing on the formulation and characterization of delivery methods for nucleic acid therapies. By providing the necessary infrastructure for collaborative research, the organization seeks to translate scientific discoveries into practical healthcare solutions. The non-profit nature of the organization introduces complexities in developing a sustainable business model. This master's thesis investigates these challenges, proposing a robust business model to ensure the organization’s longevity. Through interviews with key stakeholders including researchers, start-ups, big pharma companies, and international experts, the study examines critical aspects such as stakeholder needs, the future landscape of Advanced Therapy Medicinal Products (ATMPs), and business model strategies for non-profit entities.

The project culminates in the development of a two-layer business model canvas that differentiates programmatic operations from fundraising activities, addressing the unique complexities faced by non-profit organizations. Additionally, a flexible payment model is proposed to accommodate the financial capacities of various customer segments. The thesis concludes with recommendations for the Hub's future sustainability, emphasizing the need for continuous adaptation and strategic planning. This study contributes to the understanding of business model development for non-profit research centers and offers practical insights for the operational success of Chalmers Precision HealthTech Hub.

Popular Abstract

Shaping the Future of Medicine: Creating a Successful Business Model for a Non-Profit Organization in the Dynamic Life Science Industry

Devastating diseases like Alzheimer’s, Parkinson’s, Cancer, and Muscular Atrophy have long challenged society and the medical community. However, a new beacon of hope has emerged: Gene therapies, promising groundbreaking advances in medicine. Despite the hope that these therapies bring, a significant challenge still remains: effectively delivering these at the right location and time. Chalmers Precision HealthTech Hub is poised to tackle the challenges of effective delivery and make a significant impact. This thesis explores the complexities of crafting a business model for this non-profit organization, offering key insights and recommendations for its success.

Gene therapies represent a revolutionary breakthrough in medicine, with the potential to alter gene expression at the DNA or RNA level and address the root causes of numerous medical conditions. This innovative approach offers unprecedented hope for treating diseases previously deemed incurable. Despite the promising future for these therapies, one major challenge remains in delivering these therapies at the right place and time. Chalmers Precision HealthTech Hub, an organization on the brink of establishment, is poised to tackle this critical challenge with the ultimate vision to crack the code of delivery issues and bring about a significant leap in public health.

Recognizing the importance of collaboration between industry and academia, the Hub is committed to enhancing this partnership and providing state-of-the-art infrastructure. By facilitating dynamic partnerships and knowledge exchange, the Hub seeks to harness the collective expertise of both sectors. This collaborative approach not only fuels innovation but also fosters a sense of shared purpose, driving towards breakthrough solutions that can change lives.

While robust business models are often associated with for-profit organizations, they are equally vital for non-profits like Chalmers Precision HealthTech Hub. To bring its groundbreaking mission to life, the Hub needs a well-crafted business model that ensures long-term sustainability.

This thesis focuses on identifying and overcoming these challenges to develop a viable business model for the Chalmers Precision HealthTech Hub. Through a comprehensive literature review and interviews with experts in gene therapies, business development, and non-profit management, valuable insights were gathered. These insights informed the creation of a two-layered business model canvas, tailored to the specific needs of non-profit organizations. Additionally, an innovative payment model was devised, considering the varying financial capabilities of different customers, further enhancing the organization's reach and impact.

In conclusion, this research significantly enhances the understanding of business models in non-profit contexts and provides valuable recommendations for Chalmers Precision HealthTech Hub’s bright future. With these strategies, the organization is well-positioned to thrive, ensuring its mission to revolutionize gene therapy delivery and improve countless lives is successful.

• author: Wramås, Joel and Björsing, Ida
• supervisor: Lars Bengtsson
• organization: Innovation
• course: MMKM05 20241
• year: 2024
• type: H2 - Master's Degree (Two Years)
• subject: Technology and Engineering
• keywords: Nucleic Acid Therapies, ATMPs, Business Model, Non-profit Organization
• language: English
• id: 9157835
• date added to LUP: 2024-06-19 10:12:30
• date last changed: 2024-06-19 10:12:30