Advanced

Breathing adapted radiotherapy using optical real-time thoractic localization

Ljungqvist, Rebecca (2014)
Medical Physics Programme
Abstract
Purpose: The aim of this work is to investigate the ability of a
laser positioning system for breathing-adapted radiotherapy (BART),
also known as respiratory gating. C-RAD installed the Sentinel system
at the Sk°ane University Hospital (SUS) in Malm¨o during an appointed
time for the purpose of evaluation on the pre-clinical gating prototype.
It is also to develop a visual coaching method for the Sentinel
system and to investigate the feasibility of this coaching method, by
evaluating both reproducibility and stability for the deep-inspiration
breath hold (DIBH) technique. Furthermore, to compare two real-time
positioning systems for BART; Sentinel vs. Varian Real-time Position
Management (RPM) system. Methods and material:... (More)
Purpose: The aim of this work is to investigate the ability of a
laser positioning system for breathing-adapted radiotherapy (BART),
also known as respiratory gating. C-RAD installed the Sentinel system
at the Sk°ane University Hospital (SUS) in Malm¨o during an appointed
time for the purpose of evaluation on the pre-clinical gating prototype.
It is also to develop a visual coaching method for the Sentinel
system and to investigate the feasibility of this coaching method, by
evaluating both reproducibility and stability for the deep-inspiration
breath hold (DIBH) technique. Furthermore, to compare two real-time
positioning systems for BART; Sentinel vs. Varian Real-time Position
Management (RPM) system. Methods and material: Latency measurements
were carried out on the Sentinel and the RPM system. The
latter system is at present in clinical use at SUS in Malm¨o. A latency
measuring device was developed and constructed, using an object
of detection attached to a pneumatic piston, an AVR microprocessor,
a crystal oscillator, and eight light-emitting diodes. To evaluate
the developed visual coaching method, 19 female healthy volonteers
were recruited to perform DIBHs using both audio coaching and the
developed visual coaching method. The Sentinel system was used to
monitor the thoractic AP-PA motion for all volonteers. MATLAB was
used to read and plot data from the gating system output files. All
reproducibility and stability calculations were also done in MATLAB.
Results: All volonteers improved the reproducibility of DIBHs with
the developed visual coaching method compared to audio coaching.
38% of the volonteers had improvements less than 1 mm, 46% had
an improvement between 1   2 mm, and 15% had an improvement
larger than 2 mm. In terms of stability, 23% showed no improvement
with the developed visual coaching method. 46% had improvements
less than 1 mm, 23% had an improvement between 1   2 mm, and
8% had an improvement larger than 2 mm. For the latency measurements,
the arithmetic mean and the standard deviation was calculated
to be 192.1 ± 16.5 μs for the RPM system and 94.3 ± 16.0 μs for the
Sentinel system. Conclusions: The Sentinel system had a latency
comparable with the RPM system. Both stability and reproducibility
of DIBHs was improved using the developed visual coaching method.
The results indicate that the Sentinel system is a promising system
for BART. (Less)
Please use this url to cite or link to this publication:
author
Ljungqvist, Rebecca
supervisor
organization
year
type
H2 - Master's Degree (Two Years)
subject
language
English
id
4934418
date added to LUP
2015-01-13 18:27:57
date last changed
2015-01-13 18:27:57
@misc{4934418,
  abstract     = {Purpose: The aim of this work is to investigate the ability of a
laser positioning system for breathing-adapted radiotherapy (BART),
also known as respiratory gating. C-RAD installed the Sentinel system
at the Sk°ane University Hospital (SUS) in Malm¨o during an appointed
time for the purpose of evaluation on the pre-clinical gating prototype.
It is also to develop a visual coaching method for the Sentinel
system and to investigate the feasibility of this coaching method, by
evaluating both reproducibility and stability for the deep-inspiration
breath hold (DIBH) technique. Furthermore, to compare two real-time
positioning systems for BART; Sentinel vs. Varian Real-time Position
Management (RPM) system. Methods and material: Latency measurements
were carried out on the Sentinel and the RPM system. The
latter system is at present in clinical use at SUS in Malm¨o. A latency
measuring device was developed and constructed, using an object
of detection attached to a pneumatic piston, an AVR microprocessor,
a crystal oscillator, and eight light-emitting diodes. To evaluate
the developed visual coaching method, 19 female healthy volonteers
were recruited to perform DIBHs using both audio coaching and the
developed visual coaching method. The Sentinel system was used to
monitor the thoractic AP-PA motion for all volonteers. MATLAB was
used to read and plot data from the gating system output files. All
reproducibility and stability calculations were also done in MATLAB.
Results: All volonteers improved the reproducibility of DIBHs with
the developed visual coaching method compared to audio coaching.
38% of the volonteers had improvements less than 1 mm, 46% had
an improvement between 1   2 mm, and 15% had an improvement
larger than 2 mm. In terms of stability, 23% showed no improvement
with the developed visual coaching method. 46% had improvements
less than 1 mm, 23% had an improvement between 1   2 mm, and
8% had an improvement larger than 2 mm. For the latency measurements,
the arithmetic mean and the standard deviation was calculated
to be 192.1 ± 16.5 μs for the RPM system and 94.3 ± 16.0 μs for the
Sentinel system. Conclusions: The Sentinel system had a latency
comparable with the RPM system. Both stability and reproducibility
of DIBHs was improved using the developed visual coaching method.
The results indicate that the Sentinel system is a promising system
for BART.},
  author       = {Ljungqvist, Rebecca},
  language     = {eng},
  note         = {Student Paper},
  title        = {Breathing adapted radiotherapy using optical real-time thoractic localization},
  year         = {2014},
}