Skip to main content

LUP Student Papers

LUND UNIVERSITY LIBRARIES

Examination of suitable material for phantoms used in photoacoustics

Larsson, Malin LU and Wahldén, Klara LU (2022) EEML05 20221
Department of Biomedical Engineering
Abstract
A fundamental part of modern medicine is the ability to study and analyze images, especially for diagnostic purposes. A relatively new imaging system is photoacoustics, where laser- and ultrasound technology are combined to create images in a non-invasive way. It is absorption of the laser that is responsible for the creation of the ultrasound signal. Thus, it is the optic properties of tissue that enable differentiating. Normally it is the amplitude of the returning signal which is utilized for image contrasting in photoacoustics. Instead, this study has examined the center frequency to wavelength dependence of the returning signal. Two parameters assumed to have an effect on the center frequency spectrum are the size and colour of... (More)
A fundamental part of modern medicine is the ability to study and analyze images, especially for diagnostic purposes. A relatively new imaging system is photoacoustics, where laser- and ultrasound technology are combined to create images in a non-invasive way. It is absorption of the laser that is responsible for the creation of the ultrasound signal. Thus, it is the optic properties of tissue that enable differentiating. Normally it is the amplitude of the returning signal which is utilized for image contrasting in photoacoustics. Instead, this study has examined the center frequency to wavelength dependence of the returning signal. Two parameters assumed to have an effect on the center frequency spectrum are the size and colour of particles. The aim of this study was to investigate whether microsphere phantoms can be used to confirm this assumption. Phantoms consisting of microspheres in different sizes in the colours blue, green and transparent were created. The photoacoustic system at Lund University Hospital (VisualSonics Vevo LAZR-X, Toronto, Canada) was used to make nine measurements, during three different days, for each one of these. After analysis of the data from the amplitude of the returning signal, it was concluded that the spheres in blue and green are appropriate for future research in this field. The results from analyzing the mean and standard deviation of the center frequency was that there is a nonlinear correlation between sphere size and center frequency. There was also a distinct difference between the center frequency spectrum for the blue and green spheres. (Less)
Please use this url to cite or link to this publication:
author
Larsson, Malin LU and Wahldén, Klara LU
supervisor
organization
alternative title
Undersökning av lämpligt material för fantomer för fotoakustik
course
EEML05 20221
year
type
M2 - Bachelor Degree
subject
keywords
Photoacoustics, PIA, Center frequency spectrum
language
English
id
9090774
date added to LUP
2022-06-30 13:18:41
date last changed
2022-06-30 13:18:41
@misc{9090774,
  abstract     = {{A fundamental part of modern medicine is the ability to study and analyze images, especially for diagnostic purposes. A relatively new imaging system is photoacoustics, where laser- and ultrasound technology are combined to create images in a non-invasive way. It is absorption of the laser that is responsible for the creation of the ultrasound signal. Thus, it is the optic properties of tissue that enable differentiating. Normally it is the amplitude of the returning signal which is utilized for image contrasting in photoacoustics. Instead, this study has examined the center frequency to wavelength dependence of the returning signal. Two parameters assumed to have an effect on the center frequency spectrum are the size and colour of particles. The aim of this study was to investigate whether microsphere phantoms can be used to confirm this assumption. Phantoms consisting of microspheres in different sizes in the colours blue, green and transparent were created. The photoacoustic system at Lund University Hospital (VisualSonics Vevo LAZR-X, Toronto, Canada) was used to make nine measurements, during three different days, for each one of these. After analysis of the data from the amplitude of the returning signal, it was concluded that the spheres in blue and green are appropriate for future research in this field. The results from analyzing the mean and standard deviation of the center frequency was that there is a nonlinear correlation between sphere size and center frequency. There was also a distinct difference between the center frequency spectrum for the blue and green spheres.}},
  author       = {{Larsson, Malin and Wahldén, Klara}},
  language     = {{eng}},
  note         = {{Student Paper}},
  title        = {{Examination of suitable material for phantoms used in photoacoustics}},
  year         = {{2022}},
}