Inducerar kemiska föroreningar antibiotikaresistens?
(2023) KAKL01 20222Centre for Analysis and Synthesis
- Abstract
- Antibiotic resistance is currently a very serious and pressing issue. Grave consequences are predicted in the future if the rate of resistance development continues as today. In relation to this there are many contaminants in our environment and the grade of effects of these contaminants on antibiotic resistance is still very much unknown. The aim of this study is to give an overview on this subject and to find out if these unknown contaminants influence antibiotic resistance in the environment. A brief review on the technique used in the field to analyse these contaminants will also be given. The databases used in this literature review were LUBsearch and google scholar. Peer-reviewed publications published after 2020 regarding this topic... (More)
- Antibiotic resistance is currently a very serious and pressing issue. Grave consequences are predicted in the future if the rate of resistance development continues as today. In relation to this there are many contaminants in our environment and the grade of effects of these contaminants on antibiotic resistance is still very much unknown. The aim of this study is to give an overview on this subject and to find out if these unknown contaminants influence antibiotic resistance in the environment. A brief review on the technique used in the field to analyse these contaminants will also be given. The databases used in this literature review were LUBsearch and google scholar. Peer-reviewed publications published after 2020 regarding this topic were examined. According to the literature reviewed the contaminants that influence antibiotic resistance in the environment are as following: metals, biocides, pesticides, microplastics, and gasoline and diesel exhaust particles. But also, various physical environmental aspects influence the antibiotic resistance in the environment. The ones mentioned in this study are temperature and climate warming, antibiotic resistance genes (ARG), biochar, minerals, and earthworms. Some of the mechanisms behind the obtained antibiotic resistance attained by the bacteria due to the contaminants were cross-resistance, effecting the efflux pumps, horizontal gene transfer of ARGs and induced stress and pressure on the bacteria. There are still many knowledge gaps regarding antibiotic resistance in the environment. But it is quite clear that contaminants influence the antibiotic resistance in the environment. Therefore, more comprehensive studies are needed about these topics in every environmental niche so that global precautions can be taken. The public should also be made more aware of this. Future studies of the mechanism of bacteria and natural environment may give an insight to how antibiotic resistance in the environment can be prevented. (Less)
- Popular Abstract (Swedish)
- Kan kemiska föroreningar leda till ökad resistens hos bakterier?
I dagens samhälle kan de flesta känna en trygghet kring utvecklingen av moderna mediciner som gör att allt fler sjukdomar kan botas jämfört med innan. Varje år kan det kännas som att mänskligheten gör framsteg vad gäller den medicinska utvecklingen. Dock är det inte så att det bara görs framsteg kring läkemedel utan vissa läkemedel kommer att börja förlora sin påverkan. Det handlar om antibiotikaläkemedel. Antibiotikaresistensen ökar och det finns inte tillräckligt med studier kring vad som leder till en ökning och vad som kan göras för att minska effekten av antibiotikaresistensen. Vidare behövs det även forskning kring vilka behandlingar som kan ersätta antibiotika... (More) - Kan kemiska föroreningar leda till ökad resistens hos bakterier?
I dagens samhälle kan de flesta känna en trygghet kring utvecklingen av moderna mediciner som gör att allt fler sjukdomar kan botas jämfört med innan. Varje år kan det kännas som att mänskligheten gör framsteg vad gäller den medicinska utvecklingen. Dock är det inte så att det bara görs framsteg kring läkemedel utan vissa läkemedel kommer att börja förlora sin påverkan. Det handlar om antibiotikaläkemedel. Antibiotikaresistensen ökar och det finns inte tillräckligt med studier kring vad som leder till en ökning och vad som kan göras för att minska effekten av antibiotikaresistensen. Vidare behövs det även forskning kring vilka behandlingar som kan ersätta antibiotika medicinen för att minska den förutspådda framtida dödligheten på grund av antibiotikaresistensen. Det finns många föroreningar i vår miljö och graden av dessa föroreningars effekter på antibiotikaresistens är fortfarande väldigt oklar. Syftet med denna litteraturstudie är att ge en översikt över detta ämne och undersöka om dessa okända föroreningar påverkar antibiotikaresistens i miljön. Studie kommer även att lyfta fram tekniken som används inom fältet för att analysera dessa föroreningar. Denna litteraturstudie har genomförts genom att analysera studier avseende antibiotikaresistens i den naturliga miljön. Vad som framkommer av den granskade litteraturen är att de föroreningar som påverkar antibiotikaresistens i miljön är följande: metaller, biocider, mikroplaster samt bensin- och dieselavgaspartiklar. Dock påverkas också olika fysiska miljöaspekter antibiotikaresistensen i miljön. De som nämns i denna studie är temperatur, biokol, antibiotikaresistenta gener (ARG), mineraler och daggmaskar. Det finns fortfarande många kunskapsluckor om antibiotikaresistens i miljön. Men det är tydligt att föroreningar påverkar antibiotikaresistensen i miljön. (Less)
Please use this url to cite or link to this publication:
http://lup.lub.lu.se/student-papers/record/9107930
- author
- Chaudhry, Maria LU
- supervisor
-
- Peter Spégel LU
- organization
- course
- KAKL01 20222
- year
- 2023
- type
- M2 - Bachelor Degree
- subject
- keywords
- Antibiotic, resistance, bacteria, contaminants, environment, analytical chemistry
- language
- English
- id
- 9107930
- date added to LUP
- 2023-06-09 09:27:29
- date last changed
- 2023-06-09 09:27:29
@misc{9107930,
abstract = {{Antibiotic resistance is currently a very serious and pressing issue. Grave consequences are predicted in the future if the rate of resistance development continues as today. In relation to this there are many contaminants in our environment and the grade of effects of these contaminants on antibiotic resistance is still very much unknown. The aim of this study is to give an overview on this subject and to find out if these unknown contaminants influence antibiotic resistance in the environment. A brief review on the technique used in the field to analyse these contaminants will also be given. The databases used in this literature review were LUBsearch and google scholar. Peer-reviewed publications published after 2020 regarding this topic were examined. According to the literature reviewed the contaminants that influence antibiotic resistance in the environment are as following: metals, biocides, pesticides, microplastics, and gasoline and diesel exhaust particles. But also, various physical environmental aspects influence the antibiotic resistance in the environment. The ones mentioned in this study are temperature and climate warming, antibiotic resistance genes (ARG), biochar, minerals, and earthworms. Some of the mechanisms behind the obtained antibiotic resistance attained by the bacteria due to the contaminants were cross-resistance, effecting the efflux pumps, horizontal gene transfer of ARGs and induced stress and pressure on the bacteria. There are still many knowledge gaps regarding antibiotic resistance in the environment. But it is quite clear that contaminants influence the antibiotic resistance in the environment. Therefore, more comprehensive studies are needed about these topics in every environmental niche so that global precautions can be taken. The public should also be made more aware of this. Future studies of the mechanism of bacteria and natural environment may give an insight to how antibiotic resistance in the environment can be prevented.}},
author = {{Chaudhry, Maria}},
language = {{eng}},
note = {{Student Paper}},
title = {{Inducerar kemiska föroreningar antibiotikaresistens?}},
year = {{2023}},
}