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Label-free and non-contact platelet analysis platform

Persson, E; Johannesson, Carl LU ; Erlinge, David LU and Evander, Mikael LU (2014) 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 p.2542-2543
Abstract

We present a non-contact platelet functional analysis platform based on acoustic trapping of platelet clusters and activation monitoring using impedance spectroscopy. The system was characterized using polystyrene particles and human platelets. The system was also capable of transferring platelets from plasma into a controlled buffer. Trapped platelets were activated using 20 and 40 μM TRAP and their responses were recorded with impedance spectroscopy. The system shows great promise as a miniaturized, automatable platform for platelet analysis.

Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Acoustic trapping, Impedance spectroscopy, Platelet functional analysis
in
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
pages
2 pages
publisher
Chemical and Biological Microsystems Society
conference name
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
external identifiers
  • Scopus:84941643558
ISBN
9780979806476
language
English
LU publication?
yes
id
03c0ef74-464e-4398-a629-8b2557f4f0ac
date added to LUP
2016-04-12 13:50:30
date last changed
2016-04-12 13:50:30
@misc{03c0ef74-464e-4398-a629-8b2557f4f0ac,
  abstract     = {<p>We present a non-contact platelet functional analysis platform based on acoustic trapping of platelet clusters and activation monitoring using impedance spectroscopy. The system was characterized using polystyrene particles and human platelets. The system was also capable of transferring platelets from plasma into a controlled buffer. Trapped platelets were activated using 20 and 40 μM TRAP and their responses were recorded with impedance spectroscopy. The system shows great promise as a miniaturized, automatable platform for platelet analysis.</p>},
  author       = {Persson, E and Johannesson, Carl and Erlinge, David and Evander, Mikael},
  isbn         = {9780979806476},
  keyword      = {Acoustic trapping,Impedance spectroscopy,Platelet functional analysis},
  language     = {eng},
  pages        = {2542--2543},
  publisher    = {ARRAY(0x62be728)},
  series       = {18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014},
  title        = {Label-free and non-contact platelet analysis platform},
  year         = {2014},
}