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Proteoglycans synthesized by fetal Guinea pig chondrocytes in culture

Madsen, Kjell; Lohmander, Stefan LU ; Moskalewski, Stanislaw and Hinek, Aleksander (1978) In Connective Tissue Research 5(4). p.205-210
Abstract

Short term cultures were carried out with chondrocytes and tissue fragments from fetal guinea pig epiphyseal cartilage. Proteoglycans were isolated from these cultures and their properties were compared with those of pro-teoglycans from adult hyaline cartilage. It was concluded that the proteoglycans synthesized in culture were essentially similar to those present in cartilage matrix in vivo. The authors therefore suggest that fetal guinea pig chondrocytes cultured in monolayer or as aggregates in suspension constitute a useful system for the study of synthesis and secretion of proteoglycans. © 1978 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Connective Tissue Research
volume
5
issue
4
pages
6 pages
publisher
Taylor & Francis
external identifiers
  • Scopus:0018138631
ISSN
0300-8207
DOI
10.3109/03008207809152274
language
English
LU publication?
yes
id
0ee7b58b-289e-4c68-958a-f2f43acf16e2
date added to LUP
2016-05-04 12:45:24
date last changed
2016-07-04 10:59:33
@misc{0ee7b58b-289e-4c68-958a-f2f43acf16e2,
  abstract     = {<p>Short term cultures were carried out with chondrocytes and tissue fragments from fetal guinea pig epiphyseal cartilage. Proteoglycans were isolated from these cultures and their properties were compared with those of pro-teoglycans from adult hyaline cartilage. It was concluded that the proteoglycans synthesized in culture were essentially similar to those present in cartilage matrix in vivo. The authors therefore suggest that fetal guinea pig chondrocytes cultured in monolayer or as aggregates in suspension constitute a useful system for the study of synthesis and secretion of proteoglycans. © 1978 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.</p>},
  author       = {Madsen, Kjell and Lohmander, Stefan and Moskalewski, Stanislaw and Hinek, Aleksander},
  issn         = {0300-8207},
  language     = {eng},
  number       = {4},
  pages        = {205--210},
  publisher    = {ARRAY(0x92d3fc0)},
  series       = {Connective Tissue Research},
  title        = {Proteoglycans synthesized by fetal Guinea pig chondrocytes in culture},
  url          = {http://dx.doi.org/10.3109/03008207809152274},
  volume       = {5},
  year         = {1978},
}