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Complications to thyroid surgery: results as reported in a database from a multicenter audit comprising 3,660 patients.

Bergenfelz, Anders LU ; Jansson, S; Kristoffersson, Ann-Charlotte LU ; Mårtensson, H; Reihnér, E; Wallin, G and Lausen, I (2008) In Langenbeck's Archives of Surgery 393. p.667-673
Abstract
BACKGROUND AND AIM: During recent years, more radical surgery for thyroid disease, i.e., total instead of subtotal resection, has been evident. Results following this strategy on national levels are scarce. MATERIALS AND METHODS: From 2004 to 2006, 26 Scandinavian Departments registered 3,660 thyroid operations in a database. Risk factors for complications were analyzed with multiple logistic regression. RESULTS: After thyroidectomy, re-bleeding occurred in 2.1% and was associated with older age (OR 1.04; p < 0.0001) and male gender (OR 1.90; p = 0.014). Postoperative infection occurred in 1.6% and associated with lymph node operation (OR 8.18; p < 0.0001). Postoperative unilateral paresis of the recurrent laryngeal nerve was... (More)
BACKGROUND AND AIM: During recent years, more radical surgery for thyroid disease, i.e., total instead of subtotal resection, has been evident. Results following this strategy on national levels are scarce. MATERIALS AND METHODS: From 2004 to 2006, 26 Scandinavian Departments registered 3,660 thyroid operations in a database. Risk factors for complications were analyzed with multiple logistic regression. RESULTS: After thyroidectomy, re-bleeding occurred in 2.1% and was associated with older age (OR 1.04; p < 0.0001) and male gender (OR 1.90; p = 0.014). Postoperative infection occurred in 1.6% and associated with lymph node operation (OR 8.18; p < 0.0001). Postoperative unilateral paresis of the recurrent laryngeal nerve was diagnosed 3.9% and bilateral paresis in 0.2%. Unilateral paresis was associated with older age, intrathoracic goiter, thyreotoxicosis, and if routine laryngoscopy was practiced (OR 1.92; p = 0.0002). After 6 months, the incidence of nerve paresis was 0.97%. After bilateral thyroid surgery (n = 1,648), hypocalcaemia treated with vitamin D analogue occurred in 9.9% of the patients at the first follow-up and in 4.4% after 6 months. CONCLUSION: Complications to thyroid surgery are not uncommon. The high frequency of hypocalcaemia treated with vitamin D after 6 months is a cause of concern. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Langenbeck's Archives of Surgery
volume
393
pages
667 - 673
publisher
Springer
external identifiers
  • WOS:000259007800009
  • PMID:18633639
  • Scopus:51449087796
ISSN
1435-2451
DOI
10.1007/s00423-008-0366-7
language
English
LU publication?
yes
id
b766de57-e0f6-4a1c-af4d-5b68e8abd9b3 (old id 1181088)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/18633639?dopt=Abstract
date added to LUP
2008-08-08 16:17:18
date last changed
2016-11-20 04:22:31
@misc{b766de57-e0f6-4a1c-af4d-5b68e8abd9b3,
  abstract     = {BACKGROUND AND AIM: During recent years, more radical surgery for thyroid disease, i.e., total instead of subtotal resection, has been evident. Results following this strategy on national levels are scarce. MATERIALS AND METHODS: From 2004 to 2006, 26 Scandinavian Departments registered 3,660 thyroid operations in a database. Risk factors for complications were analyzed with multiple logistic regression. RESULTS: After thyroidectomy, re-bleeding occurred in 2.1% and was associated with older age (OR 1.04; p &lt; 0.0001) and male gender (OR 1.90; p = 0.014). Postoperative infection occurred in 1.6% and associated with lymph node operation (OR 8.18; p &lt; 0.0001). Postoperative unilateral paresis of the recurrent laryngeal nerve was diagnosed 3.9% and bilateral paresis in 0.2%. Unilateral paresis was associated with older age, intrathoracic goiter, thyreotoxicosis, and if routine laryngoscopy was practiced (OR 1.92; p = 0.0002). After 6 months, the incidence of nerve paresis was 0.97%. After bilateral thyroid surgery (n = 1,648), hypocalcaemia treated with vitamin D analogue occurred in 9.9% of the patients at the first follow-up and in 4.4% after 6 months. CONCLUSION: Complications to thyroid surgery are not uncommon. The high frequency of hypocalcaemia treated with vitamin D after 6 months is a cause of concern.},
  author       = {Bergenfelz, Anders and Jansson, S and Kristoffersson, Ann-Charlotte and Mårtensson, H and Reihnér, E and Wallin, G and Lausen, I},
  issn         = {1435-2451},
  language     = {eng},
  pages        = {667--673},
  publisher    = {ARRAY(0x90b3238)},
  series       = {Langenbeck's Archives of Surgery},
  title        = {Complications to thyroid surgery: results as reported in a database from a multicenter audit comprising 3,660 patients.},
  url          = {http://dx.doi.org/10.1007/s00423-008-0366-7},
  volume       = {393},
  year         = {2008},
}