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Infectious Agents, the Contact System, and Innate Immunity

Frick, Inga-Maria LU and Herwald, Heiko LU (2008) 41st Congress of the German-Society-for-Transfusion-Medicine-and-Immunohematology/Interdiscip linary European-Society-for-Hemapheresis-and-Hemotherapy In Progress and Challenges in Transfusion Medicine, Hemostasis, and Hemotherapy State of the Art 2008 p.60-70
Abstract
The early host response to an infection is dependent on an efficient innate immune system. The human contact system once activated at a bacterial surface results in the induction of proinflammatory reactions and the release of antimicrobial peptides, However, under severe conditions its systemic activation A may evoke the generation of pathologic levels of kinins and a consumption of contact factors, which can both contribute to the progression of the disease and cause life-threatening complications. The present review aims to give an update on the role of the contact system in infectious diseases. (C) 2008 S. Karger GmbH, Freiburg i.Br.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Contact system, Coagulation, Infectious diseases, Inflammation, immunity, Innate
in
Progress and Challenges in Transfusion Medicine, Hemostasis, and Hemotherapy State of the Art 2008
pages
60 - 70
publisher
Karger
conference name
41st Congress of the German-Society-for-Transfusion-Medicine-and-Immunohematology/Interdiscip linary European-Society-for-Hemapheresis-and-Hemotherapy
external identifiers
  • WOS:000262975400006
ISBN
978-3-8055-8659-7
language
English
LU publication?
yes
id
daff74b1-4d60-486c-a3ed-0f7859aedb75 (old id 1375786)
date added to LUP
2009-04-17 09:40:41
date last changed
2016-04-16 09:04:42
@misc{daff74b1-4d60-486c-a3ed-0f7859aedb75,
  abstract     = {The early host response to an infection is dependent on an efficient innate immune system. The human contact system once activated at a bacterial surface results in the induction of proinflammatory reactions and the release of antimicrobial peptides, However, under severe conditions its systemic activation A may evoke the generation of pathologic levels of kinins and a consumption of contact factors, which can both contribute to the progression of the disease and cause life-threatening complications. The present review aims to give an update on the role of the contact system in infectious diseases. (C) 2008 S. Karger GmbH, Freiburg i.Br.},
  author       = {Frick, Inga-Maria and Herwald, Heiko},
  isbn         = {978-3-8055-8659-7},
  keyword      = {Contact system,Coagulation,Infectious diseases,Inflammation,immunity,Innate},
  language     = {eng},
  pages        = {60--70},
  publisher    = {ARRAY(0xa790da8)},
  series       = {Progress and Challenges in Transfusion Medicine, Hemostasis, and Hemotherapy State of the Art 2008},
  title        = {Infectious Agents, the Contact System, and Innate Immunity},
  year         = {2008},
}