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Abnormal uterine artery Doppler in pregnancies suspected of a SGA fetus is related to increased risk of recurrence during next pregnancy.

Saemundsson, Ymir; Svantesson, Henrik and Gudmundsson, Saemundur LU (2009) In Acta Obstetricia et Gynecologica Scandinavica 88(7). p.814-817
Abstract
OBJECTIVE: To investigate if placental Doppler velocimetry can predict the recurrence of a small-for-gestational age (SGA) fetus in subsequent pregnancies. DESIGN: Retrospective study. SETTING: City cohort over 15 years attending a university hospital. METHODS: A total of 196 pregnancies suspected of a SGA fetus (<3rd percentile) evaluated by uterine and umbilical artery Doppler velocimetry. Blood velocity waveform was analyzed for pulsatility index (PI) as well as the uterine artery waveform for notching in early diastole. MAIN OUTCOME MEASURE: The occurrence of a SGA newborn during the succeeding pregnancy by Doppler results from the previous pregnancy. RESULTS: In the group of 196 pregnancies suspected for SGA, 27 (13.8%) delivered a... (More)
OBJECTIVE: To investigate if placental Doppler velocimetry can predict the recurrence of a small-for-gestational age (SGA) fetus in subsequent pregnancies. DESIGN: Retrospective study. SETTING: City cohort over 15 years attending a university hospital. METHODS: A total of 196 pregnancies suspected of a SGA fetus (<3rd percentile) evaluated by uterine and umbilical artery Doppler velocimetry. Blood velocity waveform was analyzed for pulsatility index (PI) as well as the uterine artery waveform for notching in early diastole. MAIN OUTCOME MEASURE: The occurrence of a SGA newborn during the succeeding pregnancy by Doppler results from the previous pregnancy. RESULTS: In the group of 196 pregnancies suspected for SGA, 27 (13.8%) delivered a SGA newborn in the following pregnancy. Thirty-seven (18.9%) of the 196 had an abnormally high PI in the uterine arteries in their first pregnancy, 12 (32.4%) of these delivered a SGA child in the next pregnancy (relative risk 3.44, p<0.001). The corresponding figure for those with normal uterine artery PI was 15 (9.4%). Abnormal umbilical artery Doppler was a worse predictor of recurrence of SGA (p=0.051). Uterine artery notching was not related to a SGA newborn during next pregnancy. CONCLUSION: The results suggest that abnormal uterine artery Doppler is related to increased risk of recurrence of SGA during the next pregnancy. This knowledge might provide the clinician with an opportunity to initiate preventive treatment and increase surveillance to women at risk during succeeding pregnancy. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Obstetricia et Gynecologica Scandinavica
volume
88
issue
7
pages
814 - 817
publisher
Wiley-Blackwell
external identifiers
  • WOS:000267202300011
  • PMID:19544201
  • Scopus:67650744674
ISSN
1600-0412
DOI
10.1080/00016340903002865
language
English
LU publication?
yes
id
8738bb6a-4cfc-4daf-b2dc-164b6f2dc5ad (old id 1434053)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19544201?dopt=Abstract
date added to LUP
2009-07-03 15:49:11
date last changed
2016-10-13 04:28:52
@misc{8738bb6a-4cfc-4daf-b2dc-164b6f2dc5ad,
  abstract     = {OBJECTIVE: To investigate if placental Doppler velocimetry can predict the recurrence of a small-for-gestational age (SGA) fetus in subsequent pregnancies. DESIGN: Retrospective study. SETTING: City cohort over 15 years attending a university hospital. METHODS: A total of 196 pregnancies suspected of a SGA fetus (&lt;3rd percentile) evaluated by uterine and umbilical artery Doppler velocimetry. Blood velocity waveform was analyzed for pulsatility index (PI) as well as the uterine artery waveform for notching in early diastole. MAIN OUTCOME MEASURE: The occurrence of a SGA newborn during the succeeding pregnancy by Doppler results from the previous pregnancy. RESULTS: In the group of 196 pregnancies suspected for SGA, 27 (13.8%) delivered a SGA newborn in the following pregnancy. Thirty-seven (18.9%) of the 196 had an abnormally high PI in the uterine arteries in their first pregnancy, 12 (32.4%) of these delivered a SGA child in the next pregnancy (relative risk 3.44, p&lt;0.001). The corresponding figure for those with normal uterine artery PI was 15 (9.4%). Abnormal umbilical artery Doppler was a worse predictor of recurrence of SGA (p=0.051). Uterine artery notching was not related to a SGA newborn during next pregnancy. CONCLUSION: The results suggest that abnormal uterine artery Doppler is related to increased risk of recurrence of SGA during the next pregnancy. This knowledge might provide the clinician with an opportunity to initiate preventive treatment and increase surveillance to women at risk during succeeding pregnancy.},
  author       = {Saemundsson, Ymir and Svantesson, Henrik and Gudmundsson, Saemundur},
  issn         = {1600-0412},
  language     = {eng},
  number       = {7},
  pages        = {814--817},
  publisher    = {ARRAY(0x9a3ddb8)},
  series       = {Acta Obstetricia et Gynecologica Scandinavica},
  title        = {Abnormal uterine artery Doppler in pregnancies suspected of a SGA fetus is related to increased risk of recurrence during next pregnancy.},
  url          = {http://dx.doi.org/10.1080/00016340903002865},
  volume       = {88},
  year         = {2009},
}