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Inadequate timing of prophylactic antibiotics in orthopedic surgery. We can do better.

Stefansdottir, Anna LU ; Robertsson, Otto LU ; W-Dahl, Annette LU ; Kiernan, Sverrir; Gustafson, Pelle LU and Lidgren, Lars LU (2009) In Acta Orthopaedica 80(6). p.633-638
Abstract
BACKGROUND AND PURPOSE: There are rising concerns about the frequency of infection after arthroplasty surgery. Prophylactic antibiotics are an important part of the preventive measures. As their effect is related to the timing of administration, it is important to follow how the routines with preoperative prophylactic antibiotics are working. METHODS: In 114 consecutive cases treated at our own university clinic in Lund during 2008, the time of administration of preoperative prophylactic antibiotic in relation to the start of surgery was recorded from a computerized operation report. In 291 other cases of primary total knee arthroplasty (TKA), randomly selected from the Swedish Knee Arthroplasty Register (SKAR), the type and dose of... (More)
BACKGROUND AND PURPOSE: There are rising concerns about the frequency of infection after arthroplasty surgery. Prophylactic antibiotics are an important part of the preventive measures. As their effect is related to the timing of administration, it is important to follow how the routines with preoperative prophylactic antibiotics are working. METHODS: In 114 consecutive cases treated at our own university clinic in Lund during 2008, the time of administration of preoperative prophylactic antibiotic in relation to the start of surgery was recorded from a computerized operation report. In 291 other cases of primary total knee arthroplasty (TKA), randomly selected from the Swedish Knee Arthroplasty Register (SKAR), the type and dose of prophylactic antibiotic as well as the time of administration in relation to the inflation of a tourniquet and to the start of surgery was recorded from anesthetic records. RESULTS: 45% (95% CI: 36-54) of the patients operated in Lund and 57% (CI: 50-64) of the TKAs randomly selected from the SKAR received the preoperative antibiotic 15-45 min before the start of surgery. 53% (CI: 46-61) received antibiotics 15-45 min before inflation of a tourniquet. INTERPRETATION: The inadequate timing of prophylactic antibiotics indicates that the standards of strict antiseptic and aseptic routines in arthroplasty surgery are falling. The use of a simple checklist to ensure the surgical safety may be one way of reducing infections in arthroplasty surgery. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Orthopaedica
volume
80
issue
6
pages
633 - 638
publisher
Taylor & Francis
external identifiers
  • WOS:000272611900002
  • PMID:19995312
  • Scopus:72549100565
ISSN
1745-3682
DOI
10.3109/17453670903316868
language
English
LU publication?
yes
id
9545c4fd-0e7c-4f86-994a-6f0e1d9e4a07 (old id 1523810)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19995312?dopt=Abstract
date added to LUP
2010-01-14 13:09:35
date last changed
2016-10-13 04:28:18
@misc{9545c4fd-0e7c-4f86-994a-6f0e1d9e4a07,
  abstract     = {BACKGROUND AND PURPOSE: There are rising concerns about the frequency of infection after arthroplasty surgery. Prophylactic antibiotics are an important part of the preventive measures. As their effect is related to the timing of administration, it is important to follow how the routines with preoperative prophylactic antibiotics are working. METHODS: In 114 consecutive cases treated at our own university clinic in Lund during 2008, the time of administration of preoperative prophylactic antibiotic in relation to the start of surgery was recorded from a computerized operation report. In 291 other cases of primary total knee arthroplasty (TKA), randomly selected from the Swedish Knee Arthroplasty Register (SKAR), the type and dose of prophylactic antibiotic as well as the time of administration in relation to the inflation of a tourniquet and to the start of surgery was recorded from anesthetic records. RESULTS: 45% (95% CI: 36-54) of the patients operated in Lund and 57% (CI: 50-64) of the TKAs randomly selected from the SKAR received the preoperative antibiotic 15-45 min before the start of surgery. 53% (CI: 46-61) received antibiotics 15-45 min before inflation of a tourniquet. INTERPRETATION: The inadequate timing of prophylactic antibiotics indicates that the standards of strict antiseptic and aseptic routines in arthroplasty surgery are falling. The use of a simple checklist to ensure the surgical safety may be one way of reducing infections in arthroplasty surgery.},
  author       = {Stefansdottir, Anna and Robertsson, Otto and W-Dahl, Annette and Kiernan, Sverrir and Gustafson, Pelle and Lidgren, Lars},
  issn         = {1745-3682},
  language     = {eng},
  number       = {6},
  pages        = {633--638},
  publisher    = {ARRAY(0x96e6570)},
  series       = {Acta Orthopaedica},
  title        = {Inadequate timing of prophylactic antibiotics in orthopedic surgery. We can do better.},
  url          = {http://dx.doi.org/10.3109/17453670903316868},
  volume       = {80},
  year         = {2009},
}