Advanced

Aktivt induceret hypotermi efter svaer traumatisk hjerneskade.

Grände, Per-Olof LU ; Welling, Karen-Lise; Eskesen, Vagn and Romner, Bertil LU (2010) In Ugeskrift for Læger 172(19). p.1437-1440
Abstract
A Cochrane metaanalysis and a study performed on children have recently confirmed that therapeutic hypothermia does not improve outcome after severe traumatic brain injury (TBI). TBI is not comparable to a short episode of global ischemia, where therapeutic hypothermia has been shown to improve outcome. The difference may be explained by the fact that hypothermia-induced stress after a traumatic brain injury reduces cerebral perfusion in the penumbra zone, where local circulation is already reduced. Thus, to date there is no indication for therapeutic hypothermia in TBI patients.
Please use this url to cite or link to this publication:
author
organization
alternative title
Actively induced hypothermia following severe traumatic brain injury
publishing date
type
Contribution to journal
publication status
published
subject
in
Ugeskrift for Læger
volume
172
issue
19
pages
1437 - 1440
publisher
Den Almindelige Danske Lægeforening
external identifiers
  • PMID:20470652
  • Scopus:77954931163
ISSN
0041-5782
language
Danish
LU publication?
yes
id
a7e2ce45-849f-42f5-83d1-2207c4f31d12 (old id 1610245)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/20470652?dopt=Abstract
date added to LUP
2010-06-01 22:33:02
date last changed
2016-11-15 13:12:31
@misc{a7e2ce45-849f-42f5-83d1-2207c4f31d12,
  abstract     = {A Cochrane metaanalysis and a study performed on children have recently confirmed that therapeutic hypothermia does not improve outcome after severe traumatic brain injury (TBI). TBI is not comparable to a short episode of global ischemia, where therapeutic hypothermia has been shown to improve outcome. The difference may be explained by the fact that hypothermia-induced stress after a traumatic brain injury reduces cerebral perfusion in the penumbra zone, where local circulation is already reduced. Thus, to date there is no indication for therapeutic hypothermia in TBI patients.},
  author       = {Grände, Per-Olof and Welling, Karen-Lise and Eskesen, Vagn and Romner, Bertil},
  issn         = {0041-5782},
  language     = {dan},
  number       = {19},
  pages        = {1437--1440},
  publisher    = {ARRAY(0x859d218)},
  series       = {Ugeskrift for Læger},
  title        = {Aktivt induceret hypotermi efter svaer traumatisk hjerneskade.},
  volume       = {172},
  year         = {2010},
}