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MicroRNAs and other small silencing RNAs in cancer.

Rovira, Carlos LU ; Güida, Maria C and Cayota, Alfonso (2010) In IUBMB Life 62(12). p.859-868
Abstract
Small noncoding RNAs are key controllers of cellular function, and their deregulation can lead to cancer development and metastatic evolution. This review summarizes the most important examples of small RNAs involved in human cancer and discusses their clinical use as biomarkers and drug targets for diagnosis, prognosis, and treatment of cancer. We also describe the possible mechanisms underlying small RNA-mediated transformation and outline the future describing new small RNA families with great potential in cancer biology. © 2010 IUBMB IUBMB Life, 2010.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
IUBMB Life
volume
62
issue
12
pages
859 - 868
publisher
Wiley-Blackwell
external identifiers
  • WOS:000285934800001
  • PMID:21154820
  • Scopus:79952028844
ISSN
1521-6543
DOI
10.1002/iub.399
language
English
LU publication?
yes
id
ce5eab4f-d958-49fb-bd56-8bd1fccd92eb (old id 1756446)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21154820?dopt=Abstract
date added to LUP
2011-01-03 15:00:24
date last changed
2016-11-16 16:37:05
@misc{ce5eab4f-d958-49fb-bd56-8bd1fccd92eb,
  abstract     = {Small noncoding RNAs are key controllers of cellular function, and their deregulation can lead to cancer development and metastatic evolution. This review summarizes the most important examples of small RNAs involved in human cancer and discusses their clinical use as biomarkers and drug targets for diagnosis, prognosis, and treatment of cancer. We also describe the possible mechanisms underlying small RNA-mediated transformation and outline the future describing new small RNA families with great potential in cancer biology. © 2010 IUBMB IUBMB Life, 2010.},
  author       = {Rovira, Carlos and Güida, Maria C and Cayota, Alfonso},
  issn         = {1521-6543},
  language     = {eng},
  number       = {12},
  pages        = {859--868},
  publisher    = {ARRAY(0x7f3e990)},
  series       = {IUBMB Life},
  title        = {MicroRNAs and other small silencing RNAs in cancer.},
  url          = {http://dx.doi.org/10.1002/iub.399},
  volume       = {62},
  year         = {2010},
}