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Vectorcardiographic lop alignment and the measurement of morphologic beat-to-beat variability in noisy signals

Åström, Magnus LU ; Carro, E; Sörnmo, Leif LU ; Laguna, P and Wohlfart, Björn LU (2000) In IEEE Transactions on Biomedical Engineering 47(4). p.497-506
Abstract
The measurement of subtle morphologic beat-to-beat variability in the electrocardiogram (ECG)/vectorcardiogram (VCG) is complicated by the presence of noise which is caused by, e.g., respiration and muscular activity. A method was recently presented which reduces the influence of such noise by performing spatial and temporal alignment of VCG loops. The alignment is performed in terms of scaling, rotation and time synchronization of the loops. Using an ECG simulation model based on propagation of action potentials in cardiac tissue, the ability of the method to separate morphologic variability of physiological origin from respiratory activity was studied. Morphologic variability was created by introducing a random variation in action... (More)
The measurement of subtle morphologic beat-to-beat variability in the electrocardiogram (ECG)/vectorcardiogram (VCG) is complicated by the presence of noise which is caused by, e.g., respiration and muscular activity. A method was recently presented which reduces the influence of such noise by performing spatial and temporal alignment of VCG loops. The alignment is performed in terms of scaling, rotation and time synchronization of the loops. Using an ECG simulation model based on propagation of action potentials in cardiac tissue, the ability of the method to separate morphologic variability of physiological origin from respiratory activity was studied. Morphologic variability was created by introducing a random variation in action potential propagation between different compartments. The results indicate that the separation of these two activities can be done accurately at low to moderate noise levels (less than 10 microV). At high noise levels, the estimation of the rotation angles was found to break down in an abrupt manner. It was also shown that the breakdown noise level is strongly dependent on loop morphology; a planar loop corresponds to a lower breakdown noise level than does a nonplanar loop. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
IEEE Transactions on Biomedical Engineering
volume
47
issue
4
pages
497 - 506
publisher
IEEE--Institute of Electrical and Electronics Engineers Inc.
external identifiers
  • Scopus:0034115507
ISSN
0018-9294
DOI
10.1109/10.828149
language
English
LU publication?
yes
id
5ab55b1f-b428-4d3f-9111-ada80992e9ad (old id 1758744)
date added to LUP
2011-01-04 10:57:58
date last changed
2016-11-27 04:28:38
@misc{5ab55b1f-b428-4d3f-9111-ada80992e9ad,
  abstract     = {The measurement of subtle morphologic beat-to-beat variability in the electrocardiogram (ECG)/vectorcardiogram (VCG) is complicated by the presence of noise which is caused by, e.g., respiration and muscular activity. A method was recently presented which reduces the influence of such noise by performing spatial and temporal alignment of VCG loops. The alignment is performed in terms of scaling, rotation and time synchronization of the loops. Using an ECG simulation model based on propagation of action potentials in cardiac tissue, the ability of the method to separate morphologic variability of physiological origin from respiratory activity was studied. Morphologic variability was created by introducing a random variation in action potential propagation between different compartments. The results indicate that the separation of these two activities can be done accurately at low to moderate noise levels (less than 10 microV). At high noise levels, the estimation of the rotation angles was found to break down in an abrupt manner. It was also shown that the breakdown noise level is strongly dependent on loop morphology; a planar loop corresponds to a lower breakdown noise level than does a nonplanar loop.},
  author       = {Åström, Magnus and Carro, E and Sörnmo, Leif and Laguna, P and Wohlfart, Björn},
  issn         = {0018-9294},
  language     = {eng},
  number       = {4},
  pages        = {497--506},
  publisher    = {ARRAY(0xa449f88)},
  series       = {IEEE Transactions on Biomedical Engineering},
  title        = {Vectorcardiographic lop alignment and the measurement of morphologic beat-to-beat variability in noisy signals},
  url          = {http://dx.doi.org/10.1109/10.828149},
  volume       = {47},
  year         = {2000},
}