Mortality and cancer morbidity among cement workers
(1993) In British Journal of Industrial Medicine 50(3). p.72-264- Abstract
- OBJECTIVE:
To explore associations between exposure to cement dust and cause specific mortality and tumour morbidity, especially gastrointestinal tumours.
DESIGN:
A retrospective cohort study.
SUBJECTS AND SETTING:
2400 men, employed for at least 12 months in two Swedish cement factories.
MAIN OUTCOME MEASURES:
Cause specific morality from death certificates (1952-86). Cancer morbidity from tumour registry information (1958-86). Standardised mortality rates (SMRs; national reference rates) and standardised morbidity incidence rates (SIRs; regional reference rates) were calculated.
RESULTS:
An increased risk of colorectal... (More) - OBJECTIVE:
To explore associations between exposure to cement dust and cause specific mortality and tumour morbidity, especially gastrointestinal tumours.
DESIGN:
A retrospective cohort study.
SUBJECTS AND SETTING:
2400 men, employed for at least 12 months in two Swedish cement factories.
MAIN OUTCOME MEASURES:
Cause specific morality from death certificates (1952-86). Cancer morbidity from tumour registry information (1958-86). Standardised mortality rates (SMRs; national reference rates) and standardised morbidity incidence rates (SIRs; regional reference rates) were calculated.
RESULTS:
An increased risk of colorectal cancer was found > or = 15 years since the start of employment (SIR 1.6, 95% confidence interval (95% CI) 1.1-2.3), mainly due to an increased risk for tumours in the right part of the colon (SIR 2.7, 95% CI 1.4-4.8), but not in the left part (SIR 1.0, 95% CI 0.3-2.5). There was a numerical increase of rectal cancer (SIR 1.5, 95% CI 0.8-2.5). Exposure (duration of blue collar employment)-response relations were found for right sided colon cancer. After > or = 25 years of cement work, the risk was fourfold (SIR 4.3, 95% CI 1.7-8.9). There was no excess of stomach cancer or respiratory cancer. Neither total mortality nor cause specific mortality were significantly increased.
CONCLUSIONS:
Diverging risk patterns for tumours with different localisations within the large bowel were found in the morbidity study. Long term exposure to cement dust was a risk factor for right sided colon cancer. The mortality study did not show this risk. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1896118
- author
- Jakobsson, Kristina LU ; Horstmann, Vibeke LU and Welinder, Hans LU
- organization
- publishing date
- 1993
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- *Cause of Death *Cohort Studies *Dust/adverse effects *Gastrointestinal Neoplasms/etiology *Gastrointestinal Neoplasms/mortality* *Humans *Male *Morbidity *Occupational Diseases/etiology *Occupational Diseases/mortality* *Occupational Exposure/adverse effects* *Retrospective Studies *Risk Factors *Silicate Cement/adverse effects* *Sweden/epidemiology *Time Factors
- in
- British Journal of Industrial Medicine
- volume
- 50
- issue
- 3
- pages
- 72 - 264
- publisher
- BMJ Publishing Group
- external identifiers
-
- scopus:0027513662
- language
- English
- LU publication?
- yes
- id
- deb87d8b-cee2-4df6-9e21-83914d84ec43 (old id 1896118)
- date added to LUP
- 2016-04-04 13:15:53
- date last changed
- 2021-01-03 10:22:43
@article{deb87d8b-cee2-4df6-9e21-83914d84ec43,
abstract = {{OBJECTIVE:<br/><br>
To explore associations between exposure to cement dust and cause specific mortality and tumour morbidity, especially gastrointestinal tumours.<br/><br>
<br/><br>
DESIGN:<br/><br>
A retrospective cohort study.<br/><br>
<br/><br>
SUBJECTS AND SETTING:<br/><br>
2400 men, employed for at least 12 months in two Swedish cement factories.<br/><br>
<br/><br>
MAIN OUTCOME MEASURES:<br/><br>
Cause specific morality from death certificates (1952-86). Cancer morbidity from tumour registry information (1958-86). Standardised mortality rates (SMRs; national reference rates) and standardised morbidity incidence rates (SIRs; regional reference rates) were calculated.<br/><br>
<br/><br>
RESULTS:<br/><br>
An increased risk of colorectal cancer was found > or = 15 years since the start of employment (SIR 1.6, 95% confidence interval (95% CI) 1.1-2.3), mainly due to an increased risk for tumours in the right part of the colon (SIR 2.7, 95% CI 1.4-4.8), but not in the left part (SIR 1.0, 95% CI 0.3-2.5). There was a numerical increase of rectal cancer (SIR 1.5, 95% CI 0.8-2.5). Exposure (duration of blue collar employment)-response relations were found for right sided colon cancer. After > or = 25 years of cement work, the risk was fourfold (SIR 4.3, 95% CI 1.7-8.9). There was no excess of stomach cancer or respiratory cancer. Neither total mortality nor cause specific mortality were significantly increased.<br/><br>
<br/><br>
CONCLUSIONS:<br/><br>
Diverging risk patterns for tumours with different localisations within the large bowel were found in the morbidity study. Long term exposure to cement dust was a risk factor for right sided colon cancer. The mortality study did not show this risk.}},
author = {{Jakobsson, Kristina and Horstmann, Vibeke and Welinder, Hans}},
keywords = {{*Cause of Death *Cohort Studies *Dust/adverse effects *Gastrointestinal Neoplasms/etiology *Gastrointestinal Neoplasms/mortality* *Humans *Male *Morbidity *Occupational Diseases/etiology *Occupational Diseases/mortality* *Occupational Exposure/adverse effects* *Retrospective Studies *Risk Factors *Silicate Cement/adverse effects* *Sweden/epidemiology *Time Factors}},
language = {{eng}},
number = {{3}},
pages = {{72--264}},
publisher = {{BMJ Publishing Group}},
series = {{British Journal of Industrial Medicine}},
title = {{Mortality and cancer morbidity among cement workers}},
volume = {{50}},
year = {{1993}},
}