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Could audiovisual training be used to improve cognition in extremely low birth weight children?

Huotilainen, Minna; Lovio, Riikka; Kujala, Teija; Tommiska, Viena; Karma, Kai and Fellman, Vineta LU (2011) In Acta paediatrica (Oslo, Norway : 1992) 100. p.1489-1494
Abstract
Aim: To study whether a dyslexia remediation programme, Audilex, improves cognition in extremely low birth (ELBW) children. Methods: Six-year-old ELBW children were allocated to a 5-week training with Audilex or playing control computer games. Before and after intervention, auditory event-related brain potentials (ERP) to sound changes were recorded and reading related skills assessed. Primary outcome was the mismatch negativity (MMN) component of ERP. Secondary outcomes were Audilex Test (ability to perform the Audilex games), the reading skills after the intervention and 2 years later. Of eligible children, 39 (54%) consented and 22 (30%) completed the protocol. Results: The MMN responses to the frequency (p = 0.02) and duration deviants... (More)
Aim: To study whether a dyslexia remediation programme, Audilex, improves cognition in extremely low birth (ELBW) children. Methods: Six-year-old ELBW children were allocated to a 5-week training with Audilex or playing control computer games. Before and after intervention, auditory event-related brain potentials (ERP) to sound changes were recorded and reading related skills assessed. Primary outcome was the mismatch negativity (MMN) component of ERP. Secondary outcomes were Audilex Test (ability to perform the Audilex games), the reading skills after the intervention and 2 years later. Of eligible children, 39 (54%) consented and 22 (30%) completed the protocol. Results: The MMN responses to the frequency (p = 0.02) and duration deviants (p < 0.01) increased after Audilex training (n = 11), but not after control game playing (n = 11). Audilex Test performance was similar in both groups. The reading skills were similar after intervention and 2 years later; word reading score 59.7, 66.8 and 74.9 and comprehensive reading score 8.1, 8.8 and 9.4 in Audilex, Control and healthy class-mate children, respectively. Conclusions: Although all children did not complete the protocol, the results suggest that training with Audilex dyslexia programme might be beneficial for enhancing neural-level sound discrimation and possibly reading skills in ELBW children. A larger trial is warranted. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta paediatrica (Oslo, Norway : 1992)
volume
100
pages
1489 - 1494
publisher
Taylor & Francis
external identifiers
  • WOS:000296421300026
  • PMID:21535135
  • Scopus:80054021231
ISSN
1651-2227
DOI
10.1111/j.1651-2227.2011.02345.x
language
English
LU publication?
yes
id
d4d7bab5-225a-4730-bd15-a92bb3e4f899 (old id 1973261)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/21535135?dopt=Abstract
date added to LUP
2011-06-07 09:46:57
date last changed
2016-10-13 04:32:40
@misc{d4d7bab5-225a-4730-bd15-a92bb3e4f899,
  abstract     = {Aim: To study whether a dyslexia remediation programme, Audilex, improves cognition in extremely low birth (ELBW) children. Methods: Six-year-old ELBW children were allocated to a 5-week training with Audilex or playing control computer games. Before and after intervention, auditory event-related brain potentials (ERP) to sound changes were recorded and reading related skills assessed. Primary outcome was the mismatch negativity (MMN) component of ERP. Secondary outcomes were Audilex Test (ability to perform the Audilex games), the reading skills after the intervention and 2 years later. Of eligible children, 39 (54%) consented and 22 (30%) completed the protocol. Results: The MMN responses to the frequency (p = 0.02) and duration deviants (p &lt; 0.01) increased after Audilex training (n = 11), but not after control game playing (n = 11). Audilex Test performance was similar in both groups. The reading skills were similar after intervention and 2 years later; word reading score 59.7, 66.8 and 74.9 and comprehensive reading score 8.1, 8.8 and 9.4 in Audilex, Control and healthy class-mate children, respectively. Conclusions: Although all children did not complete the protocol, the results suggest that training with Audilex dyslexia programme might be beneficial for enhancing neural-level sound discrimation and possibly reading skills in ELBW children. A larger trial is warranted.},
  author       = {Huotilainen, Minna and Lovio, Riikka and Kujala, Teija and Tommiska, Viena and Karma, Kai and Fellman, Vineta},
  issn         = {1651-2227},
  language     = {eng},
  pages        = {1489--1494},
  publisher    = {ARRAY(0x7b7f7f0)},
  series       = {Acta paediatrica (Oslo, Norway : 1992)},
  title        = {Could audiovisual training be used to improve cognition in extremely low birth weight children?},
  url          = {http://dx.doi.org/10.1111/j.1651-2227.2011.02345.x},
  volume       = {100},
  year         = {2011},
}