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3D geometric gel dosimetry verification of intraprostatic fiducial guided hypofractionated radiotherapy of prostate cancer

Nordström, Fredrik LU ; Ceberg, Sofie LU ; af Wetterstedt, Sacha; Nilsson, Per LU ; Ceberg, Crister LU and Bäck, Sven LU (2010) IC3DDose: The 6th International Conference on 3D Radiation Dosimetry In Journal of Physics: Conference Series 250.
Abstract
This pre-study is aimed to investigate the feasibility of a normoxic polyacrylamide gel (nPAG) dosimeter with implanted gold fiducials to evaluate the geometric precision, including setup correction strategies, in the delivery of hypofractionated treatments. For this purpose a phantom consisting of three parts was constructed: (1) the patient simulating volume, providing realistic scatter conditions and weight, (2) a bottle containing the active dosimetric volume and (3) the gold fiducials and the fiducial support structure. A 6.1 Gy prostate IMRT treatment was delivered to the phantom using the sliding-window technique. The phantom was positioned prior to the treatment using the implanted fiducials and kV on-board imaging. An overlay of... (More)
This pre-study is aimed to investigate the feasibility of a normoxic polyacrylamide gel (nPAG) dosimeter with implanted gold fiducials to evaluate the geometric precision, including setup correction strategies, in the delivery of hypofractionated treatments. For this purpose a phantom consisting of three parts was constructed: (1) the patient simulating volume, providing realistic scatter conditions and weight, (2) a bottle containing the active dosimetric volume and (3) the gold fiducials and the fiducial support structure. A 6.1 Gy prostate IMRT treatment was delivered to the phantom using the sliding-window technique. The phantom was positioned prior to the treatment using the implanted fiducials and kV on-board imaging. An overlay of the 95% isosurface of the TPS calculated dose distribution and the measured dose distribution using gel showed good agreement. The clinical target volume (CTV) was well centred inside the 95% isodose surface of the measured volume. It was shown for the evaluated case that the use of on-board imaging and integrated setup correction tools could be used to compensate for a deliberately introduced offset in CTV position. The study showed that MRI based nPAG gel dosimetry can be used to verify setup correction procedures using implanted gold fiducials. (Less)
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author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
3D verification, radiotherapy, polymer gel
in
Journal of Physics: Conference Series
volume
250
publisher
IOP Publishing
conference name
IC3DDose: The 6th International Conference on 3D Radiation Dosimetry
external identifiers
  • Scopus:78650535940
DOI
10.1088/1742-6596/250/1/012059
language
English
LU publication?
yes
id
cbe399c6-8873-4772-beeb-089e7fb86709 (old id 2213096)
alternative location
http://iopscience.iop.org/1742-6596/250/1/012059
date added to LUP
2012-03-12 09:01:38
date last changed
2016-10-13 04:48:58
@misc{cbe399c6-8873-4772-beeb-089e7fb86709,
  abstract     = {This pre-study is aimed to investigate the feasibility of a normoxic polyacrylamide gel (nPAG) dosimeter with implanted gold fiducials to evaluate the geometric precision, including setup correction strategies, in the delivery of hypofractionated treatments. For this purpose a phantom consisting of three parts was constructed: (1) the patient simulating volume, providing realistic scatter conditions and weight, (2) a bottle containing the active dosimetric volume and (3) the gold fiducials and the fiducial support structure. A 6.1 Gy prostate IMRT treatment was delivered to the phantom using the sliding-window technique. The phantom was positioned prior to the treatment using the implanted fiducials and kV on-board imaging. An overlay of the 95% isosurface of the TPS calculated dose distribution and the measured dose distribution using gel showed good agreement. The clinical target volume (CTV) was well centred inside the 95% isodose surface of the measured volume. It was shown for the evaluated case that the use of on-board imaging and integrated setup correction tools could be used to compensate for a deliberately introduced offset in CTV position. The study showed that MRI based nPAG gel dosimetry can be used to verify setup correction procedures using implanted gold fiducials.},
  author       = {Nordström, Fredrik and Ceberg, Sofie and af Wetterstedt, Sacha and Nilsson, Per and Ceberg, Crister and Bäck, Sven},
  keyword      = {3D verification,radiotherapy,polymer gel},
  language     = {eng},
  publisher    = {ARRAY(0xcf7cf88)},
  series       = {Journal of Physics: Conference Series},
  title        = {3D geometric gel dosimetry verification of intraprostatic fiducial guided hypofractionated radiotherapy of prostate cancer},
  url          = {http://dx.doi.org/10.1088/1742-6596/250/1/012059},
  volume       = {250},
  year         = {2010},
}