Advanced

Interstitial laser-induced thermotherapy: Influence of carbonization on lesion size

Sturesson, C (1998) In Lasers in Surgery and Medicine 22(1). p.51-57
Abstract
Background and Objective: The size of laser-induced coagulated lesions produced in porcine muscle in vitro using a cylindrical diffusing fiber tip and a conductive heat source, made by covering the diffuser with a hollow steel needle, were compared to investigate the influence of charring. Materials and methods: Light from a Nd: YAG laser was utilized for thermotherapy. A theoretical model for calculating tissue temperature was used to predict the experimental results and to simulate in vivo treatments. Results: The metal-covered tip produced carbonization and tissue vaporization that was not found with the diffuser. After 20 min of irradiation at a laser power of 7 W, the coagulated volumes with and without carbonization were found to be... (More)
Background and Objective: The size of laser-induced coagulated lesions produced in porcine muscle in vitro using a cylindrical diffusing fiber tip and a conductive heat source, made by covering the diffuser with a hollow steel needle, were compared to investigate the influence of charring. Materials and methods: Light from a Nd: YAG laser was utilized for thermotherapy. A theoretical model for calculating tissue temperature was used to predict the experimental results and to simulate in vivo treatments. Results: The metal-covered tip produced carbonization and tissue vaporization that was not found with the diffuser. After 20 min of irradiation at a laser power of 7 W, the coagulated volumes with and without carbonization were found to be 13.1 cm(3) (range 12.4-14.1 cm(3), n = 4) and 12.2 cm(3) (range 11.5-13.4 cm(3), n = 4), respectively. Mathematical simulations showed that in unperfused tissue, a diffusing laser heat source produces smaller lesions than does a conductive heat source at the same power, the difference in coagulated volume becoming smaller with increased treatment time and increased power. Conclusion: Using cylindrical diffusers, interstitial laser-induced thermotherapy without carbonization at the fiber tip can be as efficient as treatment with carbonization. (C) 1998 Wiley-Liss, Inc. (Less)
Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
subject
in
Lasers in Surgery and Medicine
volume
22
issue
1
pages
51 - 57
publisher
John Wiley & Sons
external identifiers
  • Scopus:0031973929
ISSN
0196-8092
DOI
10.1002/(SICI)1096-9101(1998)22:1<51::AID-LSM12>3.0.CO;2-B
language
English
LU publication?
no
id
df3975a1-6b8f-4d2d-818e-062513426b6d (old id 2259426)
date added to LUP
2012-02-09 18:59:19
date last changed
2016-10-13 04:25:41
@misc{df3975a1-6b8f-4d2d-818e-062513426b6d,
  abstract     = {Background and Objective: The size of laser-induced coagulated lesions produced in porcine muscle in vitro using a cylindrical diffusing fiber tip and a conductive heat source, made by covering the diffuser with a hollow steel needle, were compared to investigate the influence of charring. Materials and methods: Light from a Nd: YAG laser was utilized for thermotherapy. A theoretical model for calculating tissue temperature was used to predict the experimental results and to simulate in vivo treatments. Results: The metal-covered tip produced carbonization and tissue vaporization that was not found with the diffuser. After 20 min of irradiation at a laser power of 7 W, the coagulated volumes with and without carbonization were found to be 13.1 cm(3) (range 12.4-14.1 cm(3), n = 4) and 12.2 cm(3) (range 11.5-13.4 cm(3), n = 4), respectively. Mathematical simulations showed that in unperfused tissue, a diffusing laser heat source produces smaller lesions than does a conductive heat source at the same power, the difference in coagulated volume becoming smaller with increased treatment time and increased power. Conclusion: Using cylindrical diffusers, interstitial laser-induced thermotherapy without carbonization at the fiber tip can be as efficient as treatment with carbonization. (C) 1998 Wiley-Liss, Inc.},
  author       = {Sturesson, C},
  issn         = {0196-8092},
  language     = {eng},
  number       = {1},
  pages        = {51--57},
  publisher    = {ARRAY(0xa6637d0)},
  series       = {Lasers in Surgery and Medicine},
  title        = {Interstitial laser-induced thermotherapy: Influence of carbonization on lesion size},
  url          = {http://dx.doi.org/10.1002/(SICI)1096-9101(1998)22:1<51::AID-LSM12>3.0.CO;2-B},
  volume       = {22},
  year         = {1998},
}