A multicentre study on the reliability of qualitative and quantitative nail-fold videocapillaroscopy assessment.
(2012) In Rheumatology (Oxford, England) 51(4). p.749-755- Abstract
- Objective. To investigate the inter- and intra-observer reliability of both qualitative and quantitative parameters used in the assessment of nail-fold capillaroscopy images.Methods. Fifty mosaic nail-fold images of healthy controls (n = 10), patients with primary RP (n = 10) and SSc (n = 30) were assessed in random order by two blinded observers on two occasions at centres in Sweden, UK and The Netherlands. Each image was therefore scored by six observers twice.Results. Inter- and intra-observer reliability of quantitative parameters showed substantial to almost perfect agreement [inter- and intra-observer weighted κ's for the number of widened capillaries was 0.75 and 0.87 and giant capillaries was 0.84 and 0.92, intra-class correlation... (More)
- Objective. To investigate the inter- and intra-observer reliability of both qualitative and quantitative parameters used in the assessment of nail-fold capillaroscopy images.Methods. Fifty mosaic nail-fold images of healthy controls (n = 10), patients with primary RP (n = 10) and SSc (n = 30) were assessed in random order by two blinded observers on two occasions at centres in Sweden, UK and The Netherlands. Each image was therefore scored by six observers twice.Results. Inter- and intra-observer reliability of quantitative parameters showed substantial to almost perfect agreement [inter- and intra-observer weighted κ's for the number of widened capillaries was 0.75 and 0.87 and giant capillaries was 0.84 and 0.92, intra-class correlation coefficients (ICCs) for capillary density was 0.87 and 0.92 and total loop width was 0.94 and 0.98, respectively]. Qualitative parameters including architecture, avascularity, haemorrhage, crossed, ramified and bushy capillaries showed moderate to substantial inter-observer reproducibility (weighted κ ranging from 0.47 to 0.73), and substantial intra-observer repeatability (weighted κ ranging from 0.71 to 0.80), whereas the scoring of tortuous and bizarre capillaries showed poor inter-observer and substantial intra-observer agreement (inter-observer weighted κ's was 0.39 and 0.21 and intra-observer weighted κ's was 0.68 and 0.76, respectively).Conclusion. All quantitative and certain qualitative parameters are highly reliable in terms of inter- and intra-observer agreement. A combination of parameters with the highest reliability should be incorporated into future capillaroscopic scoring systems in studies of prediction and monitoring of SSc spectrum disorders. (Less)
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- author
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Rheumatology (Oxford, England)
- volume
- 51
- issue
- 4
- pages
- 749 - 755
- publisher
- Oxford University Press
- external identifiers
-
- wos:000302017200024
- pmid:22190689
- scopus:84858678453
- pmid:22190689
- ISSN
- 1462-0332
- DOI
- 10.1093/rheumatology/ker403
- language
- English
- LU publication?
- yes
- id
- 22b3730e-be91-4b49-8cc2-ba93617ab478 (old id 2273683)
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- http://www.ncbi.nlm.nih.gov/pubmed/22190689?dopt=Abstract
- date added to LUP
- 2016-04-04 09:44:28
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@article{22b3730e-be91-4b49-8cc2-ba93617ab478,
abstract = {{Objective. To investigate the inter- and intra-observer reliability of both qualitative and quantitative parameters used in the assessment of nail-fold capillaroscopy images.Methods. Fifty mosaic nail-fold images of healthy controls (n = 10), patients with primary RP (n = 10) and SSc (n = 30) were assessed in random order by two blinded observers on two occasions at centres in Sweden, UK and The Netherlands. Each image was therefore scored by six observers twice.Results. Inter- and intra-observer reliability of quantitative parameters showed substantial to almost perfect agreement [inter- and intra-observer weighted κ's for the number of widened capillaries was 0.75 and 0.87 and giant capillaries was 0.84 and 0.92, intra-class correlation coefficients (ICCs) for capillary density was 0.87 and 0.92 and total loop width was 0.94 and 0.98, respectively]. Qualitative parameters including architecture, avascularity, haemorrhage, crossed, ramified and bushy capillaries showed moderate to substantial inter-observer reproducibility (weighted κ ranging from 0.47 to 0.73), and substantial intra-observer repeatability (weighted κ ranging from 0.71 to 0.80), whereas the scoring of tortuous and bizarre capillaries showed poor inter-observer and substantial intra-observer agreement (inter-observer weighted κ's was 0.39 and 0.21 and intra-observer weighted κ's was 0.68 and 0.76, respectively).Conclusion. All quantitative and certain qualitative parameters are highly reliable in terms of inter- and intra-observer agreement. A combination of parameters with the highest reliability should be incorporated into future capillaroscopic scoring systems in studies of prediction and monitoring of SSc spectrum disorders.}},
author = {{Hofstee, Herman M A and Serné, Erik H and Roberts, Christopher and Hesselstrand, Roger and Scheja, Agneta and Moore, Tonia L and Wildt, Marie and Manning, Joanne B and Vonk Noordegraaf, Anton and Voskuyl, Alexandre E and Herrick, Ariane L}},
issn = {{1462-0332}},
language = {{eng}},
number = {{4}},
pages = {{749--755}},
publisher = {{Oxford University Press}},
series = {{Rheumatology (Oxford, England)}},
title = {{A multicentre study on the reliability of qualitative and quantitative nail-fold videocapillaroscopy assessment.}},
url = {{http://dx.doi.org/10.1093/rheumatology/ker403}},
doi = {{10.1093/rheumatology/ker403}},
volume = {{51}},
year = {{2012}},
}