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Proteoglycan epitope in synovial fluid in gonarthrosis : 28 cases of tibial osteotomy studied prospectively for 2 years

Odenbring, Sten ; Egund, Niels ; Lindstrand, Anders LU and Lohmander, Stefan LU orcid (1991) In Acta Orthopaedica 62(2). p.169-173
Abstract

High tibial osteotomy was performed for medial gonarthrosis in 28 patients. Preoperatively, and at 3, 12, and 24 months after surgery, clinical and radiographic examinations were made, and joint-fluid samples were aspirated. Arthroscopy was performed preoperatively and at 24 months. Immunoassay of proteoglycan epitope in joint fluid showed an increase in concentration at all times as compared with a reference population with normal knee joints. An increase in both the concentration and the total amount of proteoglycan epitope in joint fluid was noted at 3 months postoperatively with a return to preoperative values at later times. Regrowth of fibrocartilage did not correlate with proteoglycan epitope data

Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Knee joint, gonarthrosis
in
Acta Orthopaedica
volume
62
issue
2
pages
5 pages
publisher
Taylor & Francis
external identifiers
  • scopus:0026081919
  • pmid:1707576
ISSN
1745-3674
DOI
10.3109/17453679108999250
language
English
LU publication?
yes
id
23df1e31-94c2-4be6-8221-c48fa3affd24
date added to LUP
2016-05-04 18:17:34
date last changed
2024-01-04 02:47:14
@article{23df1e31-94c2-4be6-8221-c48fa3affd24,
  abstract     = {{<p>High tibial osteotomy was performed for medial gonarthrosis in 28 patients. Preoperatively, and at 3, 12, and 24 months after surgery, clinical and radiographic examinations were made, and joint-fluid samples were aspirated. Arthroscopy was performed preoperatively and at 24 months. Immunoassay of proteoglycan epitope in joint fluid showed an increase in concentration at all times as compared with a reference population with normal knee joints. An increase in both the concentration and the total amount of proteoglycan epitope in joint fluid was noted at 3 months postoperatively with a return to preoperative values at later times. Regrowth of fibrocartilage did not correlate with proteoglycan epitope data</p>}},
  author       = {{Odenbring, Sten and Egund, Niels and Lindstrand, Anders and Lohmander, Stefan}},
  issn         = {{1745-3674}},
  keywords     = {{Knee joint; gonarthrosis}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{169--173}},
  publisher    = {{Taylor & Francis}},
  series       = {{Acta Orthopaedica}},
  title        = {{Proteoglycan epitope in synovial fluid in gonarthrosis : 28 cases of tibial osteotomy studied prospectively for 2 years}},
  url          = {{http://dx.doi.org/10.3109/17453679108999250}},
  doi          = {{10.3109/17453679108999250}},
  volume       = {{62}},
  year         = {{1991}},
}