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Increased Risks of Coronary Heart Disease and Stroke Among Spousal Caregivers of Cancer Patients.

Ji, Jianguang LU ; Zöller, Bengt LU ; Sundquist, Kristina LU and Sundquist, Jan LU (2012) In Circulation 125(14). p.1742-1747
Abstract
BACKGROUND: Spousal caregivers of cancer patients suffer psychological and physical burdens, which may affect their risk of subsequently developing coronary heart disease (CHD) and stroke.



METHODS AND RESULTS: Cancer patients were identified in the Swedish Cancer Registry, and information on their spouses was retrieved from the Swedish Multi-Generation Register. Follow-up of caregivers was carried out from the date of the first diagnosis of cancer in their spouses through 2008. Standardized incidence ratios (SIRs) were calculated for spousal caregivers of cancer patients compared to those without an affected spouse. After the cancer diagnosis in wives, the risks of CHD, ischemic and hemorrhagic stroke in husbands were... (More)
BACKGROUND: Spousal caregivers of cancer patients suffer psychological and physical burdens, which may affect their risk of subsequently developing coronary heart disease (CHD) and stroke.



METHODS AND RESULTS: Cancer patients were identified in the Swedish Cancer Registry, and information on their spouses was retrieved from the Swedish Multi-Generation Register. Follow-up of caregivers was carried out from the date of the first diagnosis of cancer in their spouses through 2008. Standardized incidence ratios (SIRs) were calculated for spousal caregivers of cancer patients compared to those without an affected spouse. After the cancer diagnosis in wives, the risks of CHD, ischemic and hemorrhagic stroke in husbands were 1.13 (95% CI 1.10-1.16), 1.24 (95%CI 1.21-1.27) and 1.25 (95%CI 1.18-1.32), respectively. The corresponding risks in wives with an affected husband were 1.13 (95% CI 1.10-1.16), 1.29 (95%CI 1.26-1.32) and 1.27 (95%CI 1.19-1.34). The increases were consistent over time, and were more pronounced if the spouse was affected by cancer with high mortality rates, such as pancreatic and lung cancers.



CONCLUSIONS: Spousal caregivers of cancer patients have increased risks of CHD and stroke that persists over time. Clinical attention should be paid to spousal caregivers, especially those caring for cancer patients with high mortality rates. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Circulation
volume
125
issue
14
pages
1742 - 1747
publisher
Lippincott Williams & Wilkins
external identifiers
  • WOS:000302793300015
  • PMID:22415143
  • Scopus:84859525057
ISSN
1524-4539
DOI
10.1161/CIRCULATIONAHA.111.057018
language
English
LU publication?
yes
id
883345bc-1bf2-4e69-a3a6-b22594d4eef4 (old id 2431872)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/22415143?dopt=Abstract
date added to LUP
2012-04-03 10:47:16
date last changed
2016-12-04 04:41:30
@misc{883345bc-1bf2-4e69-a3a6-b22594d4eef4,
  abstract     = {BACKGROUND: Spousal caregivers of cancer patients suffer psychological and physical burdens, which may affect their risk of subsequently developing coronary heart disease (CHD) and stroke. <br/><br>
<br/><br>
METHODS AND RESULTS: Cancer patients were identified in the Swedish Cancer Registry, and information on their spouses was retrieved from the Swedish Multi-Generation Register. Follow-up of caregivers was carried out from the date of the first diagnosis of cancer in their spouses through 2008. Standardized incidence ratios (SIRs) were calculated for spousal caregivers of cancer patients compared to those without an affected spouse. After the cancer diagnosis in wives, the risks of CHD, ischemic and hemorrhagic stroke in husbands were 1.13 (95% CI 1.10-1.16), 1.24 (95%CI 1.21-1.27) and 1.25 (95%CI 1.18-1.32), respectively. The corresponding risks in wives with an affected husband were 1.13 (95% CI 1.10-1.16), 1.29 (95%CI 1.26-1.32) and 1.27 (95%CI 1.19-1.34). The increases were consistent over time, and were more pronounced if the spouse was affected by cancer with high mortality rates, such as pancreatic and lung cancers. <br/><br>
<br/><br>
CONCLUSIONS: Spousal caregivers of cancer patients have increased risks of CHD and stroke that persists over time. Clinical attention should be paid to spousal caregivers, especially those caring for cancer patients with high mortality rates.},
  author       = {Ji, Jianguang and Zöller, Bengt and Sundquist, Kristina and Sundquist, Jan},
  issn         = {1524-4539},
  language     = {eng},
  number       = {14},
  pages        = {1742--1747},
  publisher    = {ARRAY(0xa827738)},
  series       = {Circulation},
  title        = {Increased Risks of Coronary Heart Disease and Stroke Among Spousal Caregivers of Cancer Patients.},
  url          = {http://dx.doi.org/10.1161/CIRCULATIONAHA.111.057018},
  volume       = {125},
  year         = {2012},
}