Acute lung injury in acute pancreatitis - Awaiting the big leap.
(2012) In Respiratory Medicine 106(9). p.1199-1210- Abstract
- Acute lung injury is a severe complication to acute pancreatitis and a significant health problem associated with a considerable mortality. Underlying mechanisms are complex and poorly understood, although recent insights have identified several inflammatory profiles and cellular components involved to varying degrees during different phases of pancreatitis exacerbation and acute lung injury. This review aims to highlight the current understanding of the inflammatory and cellular components involved in and responsible for the associations of acute pancreatitis and acute lung injury, with the hope of thereby providing an increased understanding of the underlying mechanisms. In addition, novel experimental models of modulating the... (More)
- Acute lung injury is a severe complication to acute pancreatitis and a significant health problem associated with a considerable mortality. Underlying mechanisms are complex and poorly understood, although recent insights have identified several inflammatory profiles and cellular components involved to varying degrees during different phases of pancreatitis exacerbation and acute lung injury. This review aims to highlight the current understanding of the inflammatory and cellular components involved in and responsible for the associations of acute pancreatitis and acute lung injury, with the hope of thereby providing an increased understanding of the underlying mechanisms. In addition, novel experimental models of modulating the pancreatitis-associated acute lung injury are presented, interventions that may be of potential future clinical value. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2967618
- author
- Akbarshahi, Hamid LU ; Rosendahl, Ann LU ; Westergren-Thorsson, Gunilla LU and Andersson, Roland LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Respiratory Medicine
- volume
- 106
- issue
- 9
- pages
- 1199 - 1210
- publisher
- Elsevier
- external identifiers
-
- wos:000308768300001
- pmid:22749752
- scopus:84864603666
- pmid:22749752
- ISSN
- 1532-3064
- DOI
- 10.1016/j.rmed.2012.06.003
- language
- English
- LU publication?
- yes
- id
- 4469ffc2-4063-4df2-ad54-361a27f0546e (old id 2967618)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/22749752?dopt=Abstract
- date added to LUP
- 2016-04-04 09:14:06
- date last changed
- 2024-06-08 09:11:10
@article{4469ffc2-4063-4df2-ad54-361a27f0546e, abstract = {{Acute lung injury is a severe complication to acute pancreatitis and a significant health problem associated with a considerable mortality. Underlying mechanisms are complex and poorly understood, although recent insights have identified several inflammatory profiles and cellular components involved to varying degrees during different phases of pancreatitis exacerbation and acute lung injury. This review aims to highlight the current understanding of the inflammatory and cellular components involved in and responsible for the associations of acute pancreatitis and acute lung injury, with the hope of thereby providing an increased understanding of the underlying mechanisms. In addition, novel experimental models of modulating the pancreatitis-associated acute lung injury are presented, interventions that may be of potential future clinical value.}}, author = {{Akbarshahi, Hamid and Rosendahl, Ann and Westergren-Thorsson, Gunilla and Andersson, Roland}}, issn = {{1532-3064}}, language = {{eng}}, number = {{9}}, pages = {{1199--1210}}, publisher = {{Elsevier}}, series = {{Respiratory Medicine}}, title = {{Acute lung injury in acute pancreatitis - Awaiting the big leap.}}, url = {{http://dx.doi.org/10.1016/j.rmed.2012.06.003}}, doi = {{10.1016/j.rmed.2012.06.003}}, volume = {{106}}, year = {{2012}}, }