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Activity of pyramidal tract neurons in the cat during standing and walking on an inclined plane.

Nyström, Anastasia LU ; Beloozerova, I N; Zelenin, P V; Stout, E E; Sirota, M G; Orlovsky, G N and Deliagina, T G (2009) In Journal of Physiology 587(Pt 15). p.811-3795
Abstract
To keep balance when standing or walking on a surface inclined in the roll plane, the cat modifies its body configuration so that the functional length of its right and left limbs becomes different. The aim of the present study was to assess the motor cortex participation in the generation of this left/right asymmetry. We recorded the activity of fore- and hindlimb-related pyramidal tract neurons (PTNs) during standing and walking on a treadmill. A difference in PTN activity at two tilted positions of the treadmill (+/- 15 deg) was considered a positional response to surface inclination. During standing, 47% of PTNs exhibited a positional response, increasing their activity with either the contra-tilt (20%) or the ipsi-tilt (27%). During... (More)
To keep balance when standing or walking on a surface inclined in the roll plane, the cat modifies its body configuration so that the functional length of its right and left limbs becomes different. The aim of the present study was to assess the motor cortex participation in the generation of this left/right asymmetry. We recorded the activity of fore- and hindlimb-related pyramidal tract neurons (PTNs) during standing and walking on a treadmill. A difference in PTN activity at two tilted positions of the treadmill (+/- 15 deg) was considered a positional response to surface inclination. During standing, 47% of PTNs exhibited a positional response, increasing their activity with either the contra-tilt (20%) or the ipsi-tilt (27%). During walking, PTNs were modulated in the rhythm of stepping, and tilts of the supporting surface evoked positional responses in the form of changes to the magnitude of modulation in 58% of PTNs. The contra-tilt increased activity in 28% of PTNs, and ipsi-tilt increased activity in 30% of PTNs. We suggest that PTNs with positional responses contribute to the modifications of limb configuration that are necessary for adaptation to the inclined surface. By comparing the responses to tilts in individual PTNs during standing and walking, four groups of PTNs were revealed: responding in both tasks (30%); responding only during standing (16%); responding only during walking (30%); responding in none of the tasks (24%). This diversity suggests that common and separate cortical mechanisms are used for postural adaptation to tilts during standing and walking. (Less)
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author
publishing date
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Contribution to journal
publication status
published
subject
keywords
Postural Balance, Animal, Physical Conditioning, Neurons, Motor Cortex, Hindlimb, Forelimb, Feedback, Exercise Test, Animals, Cats, Posture, Pyramidal Tracts, Somatosensory Cortex, Walking
in
Journal of Physiology
volume
587
issue
Pt 15
pages
811 - 3795
publisher
The Physiological Society
external identifiers
  • Scopus:68149166792
ISSN
1469-7793
language
English
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31315fd5-c28e-4717-b1af-ae20122badd4 (old id 3132139)
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date added to LUP
2012-11-07 14:40:38
date last changed
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@misc{31315fd5-c28e-4717-b1af-ae20122badd4,
  abstract     = {To keep balance when standing or walking on a surface inclined in the roll plane, the cat modifies its body configuration so that the functional length of its right and left limbs becomes different. The aim of the present study was to assess the motor cortex participation in the generation of this left/right asymmetry. We recorded the activity of fore- and hindlimb-related pyramidal tract neurons (PTNs) during standing and walking on a treadmill. A difference in PTN activity at two tilted positions of the treadmill (+/- 15 deg) was considered a positional response to surface inclination. During standing, 47% of PTNs exhibited a positional response, increasing their activity with either the contra-tilt (20%) or the ipsi-tilt (27%). During walking, PTNs were modulated in the rhythm of stepping, and tilts of the supporting surface evoked positional responses in the form of changes to the magnitude of modulation in 58% of PTNs. The contra-tilt increased activity in 28% of PTNs, and ipsi-tilt increased activity in 30% of PTNs. We suggest that PTNs with positional responses contribute to the modifications of limb configuration that are necessary for adaptation to the inclined surface. By comparing the responses to tilts in individual PTNs during standing and walking, four groups of PTNs were revealed: responding in both tasks (30%); responding only during standing (16%); responding only during walking (30%); responding in none of the tasks (24%). This diversity suggests that common and separate cortical mechanisms are used for postural adaptation to tilts during standing and walking.},
  author       = {Nyström, Anastasia and Beloozerova, I N and Zelenin, P V and Stout, E E and Sirota, M G and Orlovsky, G N and Deliagina, T G},
  issn         = {1469-7793},
  keyword      = {Postural Balance,Animal,Physical Conditioning,Neurons,Motor Cortex,Hindlimb,Forelimb,Feedback,Exercise Test,Animals,Cats,Posture,Pyramidal Tracts,Somatosensory Cortex,Walking},
  language     = {eng},
  number       = {Pt 15},
  pages        = {811--3795},
  publisher    = {ARRAY(0xbc38908)},
  series       = {Journal of Physiology},
  title        = {Activity of pyramidal tract neurons in the cat during standing and walking on an inclined plane.},
  volume       = {587},
  year         = {2009},
}