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Repetitive transforaminal steroid injections in cervical radiculopathy: a prospective outcome study including 140 patients.

Persson, Liselotte and Anderberg, Leif LU (2012) In Evidence-based spine-care journal 3(3). p.13-20
Abstract
Study design: Prospective case series. Objective: To evaluate the effect of three repetitive transforaminal steroid injections in a large series of selected patients with cervical radiculopathy caused by spondylosis. Methods: Consecutively, 140 patients with long-lasting medical history, clinical findings, and MRI indicating a cervical nerve root origin based on degenerative disease and a positive selective transforaminal diagnostic nerve root blocks with local anesthetics resulting in at least 50% temporary arm pain reduction were included. Before treatment started, patients underwent a clinical examination by a neurosurgeon. All patients were followed-up and evaluated by one physiotherapist at the neurosurgery outpatient clinic. A... (More)
Study design: Prospective case series. Objective: To evaluate the effect of three repetitive transforaminal steroid injections in a large series of selected patients with cervical radiculopathy caused by spondylosis. Methods: Consecutively, 140 patients with long-lasting medical history, clinical findings, and MRI indicating a cervical nerve root origin based on degenerative disease and a positive selective transforaminal diagnostic nerve root blocks with local anesthetics resulting in at least 50% temporary arm pain reduction were included. Before treatment started, patients underwent a clinical examination by a neurosurgeon. All patients were followed-up and evaluated by one physiotherapist at the neurosurgery outpatient clinic. A designed outcome questionnaire including Neck Disability Index (NDI), Symptoms Frequency Index, and Visual Analog Scale for pain intensity were used. A series of three transforaminal steroid injections, with 3 weeks in between, were performed by a neuroradiologist using image intensifier guidance in an x-ray suite. At 12-14 weeks after the first injection, follow-up was performed. Criteria for positive response to the treatment was >50% radicular arm pain reduction. Except for occasional painkillers, no other treatment was given to the patients. Results: Positive response to the treatment was achieved in 49% (n = 69) with a significant difference in NDI and pain intensity between responders and nonresponders. Conclusions: Repetitive transforaminal steroid injections may reduce symptoms (frequency, intensity, and fewer limitations of daily living activities) of radiculopathy in patients with degenerative disease in the cervical spine at a short time follow-up. [Table: see text]. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Evidence-based spine-care journal
volume
3
issue
3
pages
13 - 20
external identifiers
  • PMID:23531493
ISSN
1663-7976
DOI
10.1055/s-0032-1327805
language
English
LU publication?
yes
id
419571e0-027c-4a76-8eba-b657cd4fb029 (old id 3627647)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/23531493?dopt=Abstract
date added to LUP
2013-04-02 13:05:50
date last changed
2016-09-20 03:34:18
@misc{419571e0-027c-4a76-8eba-b657cd4fb029,
  abstract     = {Study design: Prospective case series. Objective: To evaluate the effect of three repetitive transforaminal steroid injections in a large series of selected patients with cervical radiculopathy caused by spondylosis. Methods: Consecutively, 140 patients with long-lasting medical history, clinical findings, and MRI indicating a cervical nerve root origin based on degenerative disease and a positive selective transforaminal diagnostic nerve root blocks with local anesthetics resulting in at least 50% temporary arm pain reduction were included. Before treatment started, patients underwent a clinical examination by a neurosurgeon. All patients were followed-up and evaluated by one physiotherapist at the neurosurgery outpatient clinic. A designed outcome questionnaire including Neck Disability Index (NDI), Symptoms Frequency Index, and Visual Analog Scale for pain intensity were used. A series of three transforaminal steroid injections, with 3 weeks in between, were performed by a neuroradiologist using image intensifier guidance in an x-ray suite. At 12-14 weeks after the first injection, follow-up was performed. Criteria for positive response to the treatment was >50% radicular arm pain reduction. Except for occasional painkillers, no other treatment was given to the patients. Results: Positive response to the treatment was achieved in 49% (n = 69) with a significant difference in NDI and pain intensity between responders and nonresponders. Conclusions: Repetitive transforaminal steroid injections may reduce symptoms (frequency, intensity, and fewer limitations of daily living activities) of radiculopathy in patients with degenerative disease in the cervical spine at a short time follow-up. [Table: see text].},
  author       = {Persson, Liselotte and Anderberg, Leif},
  issn         = {1663-7976},
  language     = {eng},
  number       = {3},
  pages        = {13--20},
  series       = {Evidence-based spine-care journal},
  title        = {Repetitive transforaminal steroid injections in cervical radiculopathy: a prospective outcome study including 140 patients.},
  url          = {http://dx.doi.org/10.1055/s-0032-1327805},
  volume       = {3},
  year         = {2012},
}