Advanced

Regeneration in periodontal and endosseous implant treatment

Mayfield, Lisa LU (1998)
Abstract
In a series of clinical studies regenerative procedures for periodontal disease treatment were evaluated. A reproducibility study of probing measurements using a manual periodontal probe and 3 pressure-sensitive probes showed that measurements obtained using the manual probe were the most repeatable. This probe was therefore selected for treatment evaluation. The outcome following surgical treatment of intraosseous periodontal defects with and without EDTA root conditioning did not show any significant clinical advantage of EDTA application. Guided tissue regeneration at intraosseous periodontal defects, using a bioabsorbable membrane, did not result in predictably more probing attachment gain nor probing bone gain than conventional flap... (More)
In a series of clinical studies regenerative procedures for periodontal disease treatment were evaluated. A reproducibility study of probing measurements using a manual periodontal probe and 3 pressure-sensitive probes showed that measurements obtained using the manual probe were the most repeatable. This probe was therefore selected for treatment evaluation. The outcome following surgical treatment of intraosseous periodontal defects with and without EDTA root conditioning did not show any significant clinical advantage of EDTA application. Guided tissue regeneration at intraosseous periodontal defects, using a bioabsorbable membrane, did not result in predictably more probing attachment gain nor probing bone gain than conventional flap therapy. Radiographic analysis confirmed these results.



Regenerative techniques may also be applied in conjunction with endosseous implant treatment. Bioabsorbable membranes were applied covering exposed fixture threads at peri-implant dehiscence and fenestration defects at the time of fixture installation. Following six months of healing, surgical re-entry demonstrated a significant reduction in the number of exposed fixture threads. Clinical and radiographic conditions were evaluated approximately 2 years following incorporation of fixed reconstructions at these fixtures. Radiographs revealed significantly less marginal bone at membrane treated fixtures than at control fixtures. This was evident from abutment connection radiographs indicating that optimal bone regeneration was not achieved at all defects. However, no significant difference in the rate of radiographic bone loss following loading between control and membrane treated fixtures was observed. All fixtures were clinically stable and peri-implant tissues healthy.



The results of these studies demonstrate that clinical attachment gain and bone gain is possible but not predictable following EDTA root surface conditioning and guided tissue regeneration using a bioabsorbable membrane. Guided bone regeneration, using a bioabsorbable membrane, applied at the time of titanium fixture installation resulted in predictable bone regeneration. (Less)
Please use this url to cite or link to this publication:
author
opponent
  • Professor Lindhe, Jan, Faculty of Odontology, Gothenburg University, Sweden
organization
publishing date
type
Thesis
publication status
published
subject
keywords
Odontology, guided tissue regeneration, Pressure sensitive periodontal probe, intraosseous defects, guided bone regeneration, EDTA root surface conditioning, bioabsorbable membrane, stomatology, Odontologi
pages
50 pages
publisher
Lisa Mayfield, Department of Periodontology, Faculty of Odontology, Carl Gustafs väg 34, SE-214 21 Malmö, Sweden,
defense location
Centre for Oral Health Sciences, Faculty of Odontology, Malmö, Sweden
defense date
1998-05-20 10:15
external identifiers
  • Other:SE-LUODD5/ODPA-98/1001+50
ISBN
91-628-2916-5
language
English
LU publication?
yes
id
e5f862d5-e57d-4a68-ac92-34e865e10d89 (old id 38609)
date added to LUP
2007-08-01 15:35:09
date last changed
2016-09-19 08:45:04
@misc{e5f862d5-e57d-4a68-ac92-34e865e10d89,
  abstract     = {In a series of clinical studies regenerative procedures for periodontal disease treatment were evaluated. A reproducibility study of probing measurements using a manual periodontal probe and 3 pressure-sensitive probes showed that measurements obtained using the manual probe were the most repeatable. This probe was therefore selected for treatment evaluation. The outcome following surgical treatment of intraosseous periodontal defects with and without EDTA root conditioning did not show any significant clinical advantage of EDTA application. Guided tissue regeneration at intraosseous periodontal defects, using a bioabsorbable membrane, did not result in predictably more probing attachment gain nor probing bone gain than conventional flap therapy. Radiographic analysis confirmed these results.<br/><br>
<br/><br>
Regenerative techniques may also be applied in conjunction with endosseous implant treatment. Bioabsorbable membranes were applied covering exposed fixture threads at peri-implant dehiscence and fenestration defects at the time of fixture installation. Following six months of healing, surgical re-entry demonstrated a significant reduction in the number of exposed fixture threads. Clinical and radiographic conditions were evaluated approximately 2 years following incorporation of fixed reconstructions at these fixtures. Radiographs revealed significantly less marginal bone at membrane treated fixtures than at control fixtures. This was evident from abutment connection radiographs indicating that optimal bone regeneration was not achieved at all defects. However, no significant difference in the rate of radiographic bone loss following loading between control and membrane treated fixtures was observed. All fixtures were clinically stable and peri-implant tissues healthy.<br/><br>
<br/><br>
The results of these studies demonstrate that clinical attachment gain and bone gain is possible but not predictable following EDTA root surface conditioning and guided tissue regeneration using a bioabsorbable membrane. Guided bone regeneration, using a bioabsorbable membrane, applied at the time of titanium fixture installation resulted in predictable bone regeneration.},
  author       = {Mayfield, Lisa},
  isbn         = {91-628-2916-5},
  keyword      = {Odontology,guided tissue regeneration,Pressure sensitive periodontal probe,intraosseous defects,guided bone regeneration,EDTA root surface conditioning,bioabsorbable membrane,stomatology,Odontologi},
  language     = {eng},
  pages        = {50},
  publisher    = {ARRAY(0x90b6c70)},
  title        = {Regeneration in periodontal and endosseous implant treatment},
  year         = {1998},
}