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Primary sequence differences between Chido and Rodgers variants of tryptic C4d of the human complement system

Hellman, U.; Eggertsen, G.; Lundwall, Åke LU ; Engstrom, Å. and Sjoquist, J. (1984) In FEBS Lett 170(2). p.8-254
Abstract
Human tryptic C4d of the Chido and Rodgers variant was fragmented by cyanogen bromide and trypsin. The fragments were characterized by amino acid analysis and sequence determination. Polymorphism between the two genetic variants was detected in 5 positions. Four were closely located (residues 141, 142, 145, 146), where Leu, Ser, Ile, His occurred in the Chido variant and Pro, Cys, Leu, Asp in the Rodgers variant, respectively. In position 94 Gly was found in Chido and Asp in Rodgers. Alignment of the fragments was performed and it is concluded that tryptic C4d of both variants contains 346 residues.
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Contribution to journal
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published
subject
keywords
Polymorphism, Peptide Fragments/*genetics, Humans, Cyanogen Bromide, *Complement C4b, Complement C4/*genetics, Comparative Study, Amino Acid Sequence, Blood Group Antigens/*genetics, Genetic, Research Support, Non-U.S. Gov't, Trypsin, *Variation (Genetics)
in
FEBS Lett
volume
170
issue
2
pages
8 - 254
publisher
Wiley-Blackwell
external identifiers
  • Scopus:0021223752
language
English
LU publication?
no
id
c5ce1c5c-6343-4437-86bf-3a6cca3a175a (old id 3965049)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6723966
date added to LUP
2013-08-11 18:49:03
date last changed
2016-11-27 04:37:56
@misc{c5ce1c5c-6343-4437-86bf-3a6cca3a175a,
  abstract     = {Human tryptic C4d of the Chido and Rodgers variant was fragmented by cyanogen bromide and trypsin. The fragments were characterized by amino acid analysis and sequence determination. Polymorphism between the two genetic variants was detected in 5 positions. Four were closely located (residues 141, 142, 145, 146), where Leu, Ser, Ile, His occurred in the Chido variant and Pro, Cys, Leu, Asp in the Rodgers variant, respectively. In position 94 Gly was found in Chido and Asp in Rodgers. Alignment of the fragments was performed and it is concluded that tryptic C4d of both variants contains 346 residues.},
  author       = {Hellman, U. and Eggertsen, G. and Lundwall, Åke and Engstrom, Å. and Sjoquist, J.},
  keyword      = {Polymorphism,Peptide Fragments/*genetics,Humans,Cyanogen Bromide,*Complement C4b,Complement C4/*genetics,Comparative Study,Amino Acid Sequence,Blood Group Antigens/*genetics,Genetic,Research Support,Non-U.S. Gov't,Trypsin,*Variation (Genetics)},
  language     = {eng},
  number       = {2},
  pages        = {8--254},
  publisher    = {ARRAY(0xb8c9d88)},
  series       = {FEBS Lett},
  title        = {Primary sequence differences between Chido and Rodgers variants of tryptic C4d of the human complement system},
  volume       = {170},
  year         = {1984},
}