Advanced

Molecular cloning of human prostate specific antigen cDNA

Lundwall, Åke LU and Lilja, Hans LU (1987) In FEBS Lett 214(2). p.22-317
Abstract
A lambda gt11 clone encoding prostate specific antigen has been isolated from a human prostate cDNA library. The cDNA insert of 1415 nucleotides hybridizes specifically to a prostate mRNA species of 1.5 kb. The nucleotide sequence codes for part of a signal peptide, a short propiece and the mature protein of 237 amino acid residues. The Mr for the non-glycosylated protein was 26,089. One potential site for N-linked carbohydrate attachment was identified. The primary structure shows extensive homology with proteases of the kallikrein family.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Non-U.S. Gov't, Research Support, Prostate-Specific Antigen, Prostate/immunology, Male, Humans, DNA/*genetics, Molecular, Cloning, Base Sequence, Amino Acid Sequence, Antigens/*genetics
in
FEBS Lett
volume
214
issue
2
pages
22 - 317
publisher
Wiley-Blackwell
external identifiers
  • Scopus:0023218055
language
English
LU publication?
yes
id
423eadf8-a253-48f6-bbb5-250d1b28e139 (old id 3965150)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2436946
date added to LUP
2013-08-11 18:45:37
date last changed
2016-12-04 04:47:50
@misc{423eadf8-a253-48f6-bbb5-250d1b28e139,
  abstract     = {A lambda gt11 clone encoding prostate specific antigen has been isolated from a human prostate cDNA library. The cDNA insert of 1415 nucleotides hybridizes specifically to a prostate mRNA species of 1.5 kb. The nucleotide sequence codes for part of a signal peptide, a short propiece and the mature protein of 237 amino acid residues. The Mr for the non-glycosylated protein was 26,089. One potential site for N-linked carbohydrate attachment was identified. The primary structure shows extensive homology with proteases of the kallikrein family.},
  author       = {Lundwall, Åke and Lilja, Hans},
  keyword      = {Non-U.S. Gov't,Research Support,Prostate-Specific Antigen,Prostate/immunology,Male,Humans,DNA/*genetics,Molecular,Cloning,Base Sequence,Amino Acid Sequence,Antigens/*genetics},
  language     = {eng},
  number       = {2},
  pages        = {22--317},
  publisher    = {ARRAY(0xa8099f8)},
  series       = {FEBS Lett},
  title        = {Molecular cloning of human prostate specific antigen cDNA},
  volume       = {214},
  year         = {1987},
}