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Molecular cloning of human prostate specific antigen cDNA

Lundwall, Åke LU and Lilja, Hans LU orcid (1987) In FEBS Letters 214(2). p.22-317
Abstract
A lambda gt11 clone encoding prostate specific antigen has been isolated from a human prostate cDNA library. The cDNA insert of 1415 nucleotides hybridizes specifically to a prostate mRNA species of 1.5 kb. The nucleotide sequence codes for part of a signal peptide, a short propiece and the mature protein of 237 amino acid residues. The Mr for the non-glycosylated protein was 26,089. One potential site for N-linked carbohydrate attachment was identified. The primary structure shows extensive homology with proteases of the kallikrein family.
Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Non-U.S. Gov't, Research Support, Prostate-Specific Antigen, Prostate/immunology, Male, Humans, DNA/*genetics, Molecular, Cloning, Base Sequence, Amino Acid Sequence, Antigens/*genetics
in
FEBS Letters
volume
214
issue
2
pages
22 - 317
publisher
Wiley-Blackwell
external identifiers
  • scopus:0023218055
ISSN
1873-3468
language
English
LU publication?
yes
additional info
2
id
423eadf8-a253-48f6-bbb5-250d1b28e139 (old id 3965150)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2436946
date added to LUP
2016-04-04 13:47:13
date last changed
2021-09-19 04:03:20
@article{423eadf8-a253-48f6-bbb5-250d1b28e139,
  abstract     = {{A lambda gt11 clone encoding prostate specific antigen has been isolated from a human prostate cDNA library. The cDNA insert of 1415 nucleotides hybridizes specifically to a prostate mRNA species of 1.5 kb. The nucleotide sequence codes for part of a signal peptide, a short propiece and the mature protein of 237 amino acid residues. The Mr for the non-glycosylated protein was 26,089. One potential site for N-linked carbohydrate attachment was identified. The primary structure shows extensive homology with proteases of the kallikrein family.}},
  author       = {{Lundwall, Åke and Lilja, Hans}},
  issn         = {{1873-3468}},
  keywords     = {{Non-U.S. Gov't; Research Support; Prostate-Specific Antigen; Prostate/immunology; Male; Humans; DNA/*genetics; Molecular; Cloning; Base Sequence; Amino Acid Sequence; Antigens/*genetics}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{22--317}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{FEBS Letters}},
  title        = {{Molecular cloning of human prostate specific antigen cDNA}},
  url          = {{http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2436946}},
  volume       = {{214}},
  year         = {{1987}},
}