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Progressive decline in renal function induces a gradual decrease in total hemoglobin and exercise capacity

Clyne, N. LU ; Jogestrand, T.; Lins, L. E. and Pehrsson, S. K. (1994) In Nephron 67(3). p.322-326
Abstract

We examined 58 patients (38 men, 20 women; mean age: 45 ± 12 years, body mass index: 24 ± 4 kg/m2) with a glomerular filtration rate (GFR) ranging from 3 to 32 ml/min, in order to determine the effects of a progressive decline in renal function on total hemoglobin (THb) and exercise capacity. The THb ranged from 185 to 759 g and the hemoglobin concentration ranged from 66 to 151 g/l. Maximal exercise capacity ranged from 50 to 260 W (40-143% of the expected norm). Nearly all the patients interrupted their exercise tests due to general fatigue, leg tiredness or a combination of these factors. There was a significant partial correlation between THb and GFR after sex and age had been accounted for (r = 0.39; p <0.005).... (More)

We examined 58 patients (38 men, 20 women; mean age: 45 ± 12 years, body mass index: 24 ± 4 kg/m2) with a glomerular filtration rate (GFR) ranging from 3 to 32 ml/min, in order to determine the effects of a progressive decline in renal function on total hemoglobin (THb) and exercise capacity. The THb ranged from 185 to 759 g and the hemoglobin concentration ranged from 66 to 151 g/l. Maximal exercise capacity ranged from 50 to 260 W (40-143% of the expected norm). Nearly all the patients interrupted their exercise tests due to general fatigue, leg tiredness or a combination of these factors. There was a significant partial correlation between THb and GFR after sex and age had been accounted for (r = 0.39; p <0.005). Maximal exercise capacity and THb showed a significant partial correlation after sex, age and GFR had been accounted for (r = 0.27; p

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author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Chronic renal failure, Exercise capacity, Glomerular filtration rate, Hemoglobin total
in
Nephron
volume
67
issue
3
pages
5 pages
publisher
Karger
external identifiers
  • Scopus:0028229862
ISSN
0028-2766
language
English
LU publication?
no
id
3c2e73da-f777-4cd8-b780-04ba7dcb24d3
date added to LUP
2016-08-30 22:03:29
date last changed
2016-09-16 15:09:49
@misc{3c2e73da-f777-4cd8-b780-04ba7dcb24d3,
  abstract     = {<p>We examined 58 patients (38 men, 20 women; mean age: 45 ± 12 years, body mass index: 24 ± 4 kg/m<sup>2</sup>) with a glomerular filtration rate (GFR) ranging from 3 to 32 ml/min, in order to determine the effects of a progressive decline in renal function on total hemoglobin (THb) and exercise capacity. The THb ranged from 185 to 759 g and the hemoglobin concentration ranged from 66 to 151 g/l. Maximal exercise capacity ranged from 50 to 260 W (40-143% of the expected norm). Nearly all the patients interrupted their exercise tests due to general fatigue, leg tiredness or a combination of these factors. There was a significant partial correlation between THb and GFR after sex and age had been accounted for (r = 0.39; p &lt;0.005). Maximal exercise capacity and THb showed a significant partial correlation after sex, age and GFR had been accounted for (r = 0.27; p</p>},
  author       = {Clyne, N. and Jogestrand, T. and Lins, L. E. and Pehrsson, S. K.},
  issn         = {0028-2766},
  keyword      = {Chronic renal failure,Exercise capacity,Glomerular filtration rate,Hemoglobin total},
  language     = {eng},
  number       = {3},
  pages        = {322--326},
  publisher    = {ARRAY(0x7d41100)},
  series       = {Nephron},
  title        = {Progressive decline in renal function induces a gradual decrease in total hemoglobin and exercise capacity},
  volume       = {67},
  year         = {1994},
}