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MR imaging of absorbed dose distributions for radiotherapy using ferrous sulphate gels

Olsson, L E LU ; Fransson, A; Ericsson, A and Mattsson, S LU (1990) In Physics in Medicine and Biology 35(12). p.1623-31
Abstract

The measurement of absorbed dose distributions using dosemeter gel and magnetic resonance imaging (MRI) in a standard geometry has been investigated. Absorbed depth-dose curves and profiles measured with this new technique show good agreement with corresponding measurements using diodes. This was proven in a 60Co beam as well as an electron beam. The dosemeter gel is made of agarose and ferrous sulphate solution. The dose response is linear (r = 0.9996) in the investigated dose interval, 0-40 Gy. The sensitivity is a factor of about six higher compared to ordinary ferrous sulphate solution, known as 'Fricke'. This is a true 3D dose measurement technique which will have a number of applications in radiation therapy, since it is possible... (More)

The measurement of absorbed dose distributions using dosemeter gel and magnetic resonance imaging (MRI) in a standard geometry has been investigated. Absorbed depth-dose curves and profiles measured with this new technique show good agreement with corresponding measurements using diodes. This was proven in a 60Co beam as well as an electron beam. The dosemeter gel is made of agarose and ferrous sulphate solution. The dose response is linear (r = 0.9996) in the investigated dose interval, 0-40 Gy. The sensitivity is a factor of about six higher compared to ordinary ferrous sulphate solution, known as 'Fricke'. This is a true 3D dose measurement technique which will have a number of applications in radiation therapy, since it is possible to mould the gel to arbitrary geometries, mix different radiation qualities and integrate the absorbed dose from different kinds of fields.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Dose-Response Relationship, Radiation, Ferrous Compounds, Gels, Humans, Magnetic Resonance Imaging, Models, Structural, Radiometry, Sensitivity and Specificity, Sepharose
in
Physics in Medicine and Biology
volume
35
issue
12
pages
9 pages
publisher
IOP Publishing
external identifiers
  • Scopus:0025203008
ISSN
0031-9155
DOI
10.1088/0031-9155/35/12/003
language
English
LU publication?
yes
id
3e17cdc1-ae19-4dc0-bbff-4e5301ba03ae
date added to LUP
2016-08-16 12:17:51
date last changed
2016-09-15 11:02:08
@misc{3e17cdc1-ae19-4dc0-bbff-4e5301ba03ae,
  abstract     = {<p>The measurement of absorbed dose distributions using dosemeter gel and magnetic resonance imaging (MRI) in a standard geometry has been investigated. Absorbed depth-dose curves and profiles measured with this new technique show good agreement with corresponding measurements using diodes. This was proven in a 60Co beam as well as an electron beam. The dosemeter gel is made of agarose and ferrous sulphate solution. The dose response is linear (r = 0.9996) in the investigated dose interval, 0-40 Gy. The sensitivity is a factor of about six higher compared to ordinary ferrous sulphate solution, known as 'Fricke'. This is a true 3D dose measurement technique which will have a number of applications in radiation therapy, since it is possible to mould the gel to arbitrary geometries, mix different radiation qualities and integrate the absorbed dose from different kinds of fields.</p>},
  author       = {Olsson, L E and Fransson, A and Ericsson, A and Mattsson, S},
  issn         = {0031-9155},
  keyword      = {Dose-Response Relationship, Radiation,Ferrous Compounds,Gels,Humans,Magnetic Resonance Imaging,Models, Structural,Radiometry,Sensitivity and Specificity,Sepharose},
  language     = {eng},
  number       = {12},
  pages        = {1623--31},
  publisher    = {ARRAY(0xa0c0178)},
  series       = {Physics in Medicine and Biology},
  title        = {MR imaging of absorbed dose distributions for radiotherapy using ferrous sulphate gels},
  url          = {http://dx.doi.org/10.1088/0031-9155/35/12/003 },
  volume       = {35},
  year         = {1990},
}