Advanced

Arterial diameter change measurements in premature rabbit pups using B-Mode images

Segstedt, Simon LU ; Erlöv, Tobias LU ; Milton, Patrik LU ; Sveinsdottir, Snjolaug; Jansson, Tomas LU ; Persson, Hans W LU ; Ley, David and Cinthio, Magnus LU (2012) IEEE International Ultrasonics Symposium, 2012 In 2012 IEEE International Ultrasonics Symposium (IUS) p.922-924
Abstract
To further promote cardiovascular research there is a growing need for arterial characterization on small animals. Arterial wall movement measurements form the basis for most stiffness related parameters. As far as we know, previous reports on lumen diameter change measurements in small animals have required ECG triggering and cross-correlation techniques on the RF-signal using extremely high frame rate. The first aim of this study was to evaluate a novel method, ARTerIal Characterization (ARTIC), for robust diameter measurements in premature rabbit pups using conventional scanning technique (B-mode, 230 Hz). Although blood pressure is important for arterial stiffness measurements, it is often impossible to obtain without affecting the... (More)
To further promote cardiovascular research there is a growing need for arterial characterization on small animals. Arterial wall movement measurements form the basis for most stiffness related parameters. As far as we know, previous reports on lumen diameter change measurements in small animals have required ECG triggering and cross-correlation techniques on the RF-signal using extremely high frame rate. The first aim of this study was to evaluate a novel method, ARTerIal Characterization (ARTIC), for robust diameter measurements in premature rabbit pups using conventional scanning technique (B-mode, 230 Hz). Although blood pressure is important for arterial stiffness measurements, it is often impossible to obtain without affecting the animal setup. However, arterial stiffness can also be assessed by measuring the pressure independent transition strain as recently proposed by Danpinid et al. (Ultrasonics 50, 2010: 654-665). The second aim was to investigate the feasibility of measuring transition strain in premature rabbit pups using the obtained diameter curve. The diameter was 874/82 mu m (mean/SD), CV 2.9%. The distension was 24+/-3 mu m, CV 7.3%. The transition strain was 1.55+/-0.46%, CV 12.8%. In summary, ARTIC can measure arterial diameter and distension in small animals using B-Mode images at regular frame rates. ARTIC also has a low computation time suitable for real-time implementation. Measurements of transition strain on premature rabbit pups are feasible using B-Mode images at regular frame rate. (Abstract) (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
arterial diameter, rabbit aorta, high-frequency ultrasound, tranistion, strain, B-Mode, distension
in
2012 IEEE International Ultrasonics Symposium (IUS)
pages
922 - 924
publisher
IEEE--Institute of Electrical and Electronics Engineers Inc.
conference name
IEEE International Ultrasonics Symposium, 2012
external identifiers
  • WOS:000326960200189
  • Scopus:84882419759
DOI
10.1109/ULTSYM.2012.0230
language
English
LU publication?
yes
id
37eb6b04-788a-4c45-b977-ec2b619537fb (old id 4275366)
date added to LUP
2014-01-28 11:00:52
date last changed
2016-10-13 04:47:29
@misc{37eb6b04-788a-4c45-b977-ec2b619537fb,
  abstract     = {To further promote cardiovascular research there is a growing need for arterial characterization on small animals. Arterial wall movement measurements form the basis for most stiffness related parameters. As far as we know, previous reports on lumen diameter change measurements in small animals have required ECG triggering and cross-correlation techniques on the RF-signal using extremely high frame rate. The first aim of this study was to evaluate a novel method, ARTerIal Characterization (ARTIC), for robust diameter measurements in premature rabbit pups using conventional scanning technique (B-mode, 230 Hz). Although blood pressure is important for arterial stiffness measurements, it is often impossible to obtain without affecting the animal setup. However, arterial stiffness can also be assessed by measuring the pressure independent transition strain as recently proposed by Danpinid et al. (Ultrasonics 50, 2010: 654-665). The second aim was to investigate the feasibility of measuring transition strain in premature rabbit pups using the obtained diameter curve. The diameter was 874/82 mu m (mean/SD), CV 2.9%. The distension was 24+/-3 mu m, CV 7.3%. The transition strain was 1.55+/-0.46%, CV 12.8%. In summary, ARTIC can measure arterial diameter and distension in small animals using B-Mode images at regular frame rates. ARTIC also has a low computation time suitable for real-time implementation. Measurements of transition strain on premature rabbit pups are feasible using B-Mode images at regular frame rate. (Abstract)},
  author       = {Segstedt, Simon and Erlöv, Tobias and Milton, Patrik and Sveinsdottir, Snjolaug and Jansson, Tomas and Persson, Hans W and Ley, David and Cinthio, Magnus},
  keyword      = {arterial diameter,rabbit aorta,high-frequency ultrasound,tranistion,strain,B-Mode,distension},
  language     = {eng},
  pages        = {922--924},
  publisher    = {ARRAY(0xb4fd088)},
  series       = {2012 IEEE International Ultrasonics Symposium (IUS)},
  title        = {Arterial diameter change measurements in premature rabbit pups using B-Mode images},
  url          = {http://dx.doi.org/10.1109/ULTSYM.2012.0230},
  year         = {2012},
}