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The role of Fusobacterium necrophorum in pharyngotonsillitis – A review

Holm, Karin LU ; Bank, Steffen; Nielsen, Hanne; Kristensen, Lena Hagelskjær; Prag, Jørgen and Jensen, Anders (2016) In Anaerobe
Abstract

Fusobacterium necrophorum is a gram-negative anaerobic bacterium that is the causative agent of the invasive disease Lemierre's syndrome. In addition, it is also associated with peritonsillar abscess formation and otitis media in small children. Recent research has shown that F. necrophorum may be involved in pharyngotonsillitis especially in adolescent and young adults and that it may be the second most common bacterial cause of pharyngotonsillitis after Streptococcus pyogenes (Group A streptococci). Peritonsillar abscesses and Lemierre's syndrome due to F. necrophorum are also found in this age group, suggesting that they may be complications of F. necrophorum pharyngotonsillitis. In this review we present the present knowledge about... (More)

Fusobacterium necrophorum is a gram-negative anaerobic bacterium that is the causative agent of the invasive disease Lemierre's syndrome. In addition, it is also associated with peritonsillar abscess formation and otitis media in small children. Recent research has shown that F. necrophorum may be involved in pharyngotonsillitis especially in adolescent and young adults and that it may be the second most common bacterial cause of pharyngotonsillitis after Streptococcus pyogenes (Group A streptococci). Peritonsillar abscesses and Lemierre's syndrome due to F. necrophorum are also found in this age group, suggesting that they may be complications of F. necrophorum pharyngotonsillitis. In this review we present the present knowledge about the role of F. necrophorum in pharyngotonsillitis with special emphasis on the age distribution. We argue that F. necrophorum is an important pathogen involved in pharyngotonsillitis in the age group of 13–40 years of age and we urge clinical microbiology labs to set up the appropriate techniques to be able to detect F. necrophorum from throat swabs.

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
Fusobacterium necrophorum, Lemierre, Lemierre's syndrome, Peritonsillar abscess, Pharyngitis, Pharyngotonsillitis, Tonsillitis
in
Anaerobe
pages
9 pages
publisher
Elsevier
external identifiers
  • Scopus:84988910367
ISSN
1075-9964
DOI
10.1016/j.anaerobe.2016.09.006
language
English
LU publication?
yes
id
52cfbad5-8329-414a-9a0d-e569018ceacf
date added to LUP
2016-10-12 13:40:11
date last changed
2016-10-13 07:49:47
@misc{52cfbad5-8329-414a-9a0d-e569018ceacf,
  abstract     = {<p>Fusobacterium necrophorum is a gram-negative anaerobic bacterium that is the causative agent of the invasive disease Lemierre's syndrome. In addition, it is also associated with peritonsillar abscess formation and otitis media in small children. Recent research has shown that F. necrophorum may be involved in pharyngotonsillitis especially in adolescent and young adults and that it may be the second most common bacterial cause of pharyngotonsillitis after Streptococcus pyogenes (Group A streptococci). Peritonsillar abscesses and Lemierre's syndrome due to F. necrophorum are also found in this age group, suggesting that they may be complications of F. necrophorum pharyngotonsillitis. In this review we present the present knowledge about the role of F. necrophorum in pharyngotonsillitis with special emphasis on the age distribution. We argue that F. necrophorum is an important pathogen involved in pharyngotonsillitis in the age group of 13–40 years of age and we urge clinical microbiology labs to set up the appropriate techniques to be able to detect F. necrophorum from throat swabs.</p>},
  author       = {Holm, Karin and Bank, Steffen and Nielsen, Hanne and Kristensen, Lena Hagelskjær and Prag, Jørgen and Jensen, Anders},
  issn         = {1075-9964},
  keyword      = {Fusobacterium necrophorum,Lemierre,Lemierre's syndrome,Peritonsillar abscess,Pharyngitis,Pharyngotonsillitis,Tonsillitis},
  language     = {eng},
  month        = {09},
  pages        = {9},
  publisher    = {ARRAY(0xa2c8578)},
  series       = {Anaerobe},
  title        = {The role of Fusobacterium necrophorum in pharyngotonsillitis – A review},
  url          = {http://dx.doi.org/10.1016/j.anaerobe.2016.09.006},
  year         = {2016},
}