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Maternal carriership of factor V Leiden associated with pathological uterine artery doppler measurements during pregnancy

Lindqvist, Pelle LU and Gudmundsson, Saemundur LU (2001) In BJOG : an international journal of obstetrics and gynaecology 108(10). p.5-1103
Abstract
Abstract

To determine whether increased vascular resistance in the uterine artery is associated with carriership of factor V Leiden, a retrospective study was undertaken of 231 pregnant women who were monitored with Doppler velocimetry of the uterine arteries. These women had been part of a prospective study of 2,480 pregnant women in whom factor V Leiden had been analysed. When compared with non-carriers of factor V Leiden, carriers had a tendency towards an increased proportion of pathological Doppler measurements, including a significant increase in bilateral uterine artery notches (7/33 vs 16/198, relative risk 3.1; 95% CI 1.2-8.1). This suggests an increased vascular resistance in the uteroplacental circulation among carriers... (More)
Abstract

To determine whether increased vascular resistance in the uterine artery is associated with carriership of factor V Leiden, a retrospective study was undertaken of 231 pregnant women who were monitored with Doppler velocimetry of the uterine arteries. These women had been part of a prospective study of 2,480 pregnant women in whom factor V Leiden had been analysed. When compared with non-carriers of factor V Leiden, carriers had a tendency towards an increased proportion of pathological Doppler measurements, including a significant increase in bilateral uterine artery notches (7/33 vs 16/198, relative risk 3.1; 95% CI 1.2-8.1). This suggests an increased vascular resistance in the uteroplacental circulation among carriers of factor V Leiden. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
BJOG : an international journal of obstetrics and gynaecology
volume
108
issue
10
pages
5 - 1103
publisher
Wiley-Blackwell
external identifiers
  • Scopus:0034793160
ISSN
1471-0528
language
English
LU publication?
yes
id
d8e1e3af-3053-4f22-aeb1-f95fb02bffd2 (old id 608867)
alternative location
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=11702845
date added to LUP
2012-12-27 13:23:29
date last changed
2016-10-13 04:59:00
@misc{d8e1e3af-3053-4f22-aeb1-f95fb02bffd2,
  abstract     = {Abstract<br/><br>
To determine whether increased vascular resistance in the uterine artery is associated with carriership of factor V Leiden, a retrospective study was undertaken of 231 pregnant women who were monitored with Doppler velocimetry of the uterine arteries. These women had been part of a prospective study of 2,480 pregnant women in whom factor V Leiden had been analysed. When compared with non-carriers of factor V Leiden, carriers had a tendency towards an increased proportion of pathological Doppler measurements, including a significant increase in bilateral uterine artery notches (7/33 vs 16/198, relative risk 3.1; 95% CI 1.2-8.1). This suggests an increased vascular resistance in the uteroplacental circulation among carriers of factor V Leiden.},
  author       = {Lindqvist, Pelle and Gudmundsson, Saemundur},
  issn         = {1471-0528},
  language     = {eng},
  number       = {10},
  pages        = {5--1103},
  publisher    = {ARRAY(0x87c2b78)},
  series       = {BJOG : an international journal of obstetrics and gynaecology},
  title        = {Maternal carriership of factor V Leiden associated with pathological uterine artery doppler measurements during pregnancy},
  volume       = {108},
  year         = {2001},
}