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Report of a consensus meeting on human brain temperature after severe traumatic brain injury : Its measurement and management during pyrexia

Childs, Charmaine; Wieloch, Tadeusz LU ; Lecky, Fiona; Machin, Graham; Harris, Bridget and Stocchetti, Nino (2010) In Frontiers in Neurology NOV.
Abstract

Temperature disturbances are common in patients with severe traumatic brain injury. The possibility of an adaptive, potentially beneficial role for fever in patients with severe brain trauma has been dismissed, but without good justification. Fever might, in some patients, confer benefit. A cadre of clinicians and scientists met to debate the clinically relevant, but often controversial issue about whether raised brain temperature after human traumatic brain injury (TBI) should be regarded as "good or bad" for outcome. The objective was to produce a consensus document of views about current temperature measurement and pyrexia treatment. Lectures were delivered by invited speakers with National and International publication track records... (More)

Temperature disturbances are common in patients with severe traumatic brain injury. The possibility of an adaptive, potentially beneficial role for fever in patients with severe brain trauma has been dismissed, but without good justification. Fever might, in some patients, confer benefit. A cadre of clinicians and scientists met to debate the clinically relevant, but often controversial issue about whether raised brain temperature after human traumatic brain injury (TBI) should be regarded as "good or bad" for outcome. The objective was to produce a consensus document of views about current temperature measurement and pyrexia treatment. Lectures were delivered by invited speakers with National and International publication track records in thermoregulation, neuroscience, epidemiology, measurement standards and neurocritical care. Summaries of the lectures and workshop discussions were produced from transcriptions of the lectures and workshop discussions. At the close of meeting, there was agreement on four key issues relevant to modern temperature measurement and management and for undergirding of an evidence-based practice, culminating in a consensus statement. There is no robust scientific data to support the use of hypothermia in patients whose intracranial pressure is controllable using standard therapy. A randomized clinical trial is justified to establish if body cooling for control of pyrexia (to normothermia) vs moderate pyrexia leads to a better patient outcome for TBI patients. © 2010 Childs, Wieloch, Lecky, Machin, Harris and Stocchetti.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Brain temperature, Cooling, Fever, Measurement, Pyrexia
in
Frontiers in Neurology
volume
NOV
publisher
Frontiers
external identifiers
  • Scopus:79954548946
ISSN
1664-2295
DOI
10.3389/fneur.2010.00146
language
English
LU publication?
yes
id
69cfe8da-2946-42c6-b0bb-c4cf92db9e17
date added to LUP
2016-10-05 15:02:48
date last changed
2016-10-10 14:13:21
@misc{69cfe8da-2946-42c6-b0bb-c4cf92db9e17,
  abstract     = {<p>Temperature disturbances are common in patients with severe traumatic brain injury. The possibility of an adaptive, potentially beneficial role for fever in patients with severe brain trauma has been dismissed, but without good justification. Fever might, in some patients, confer benefit. A cadre of clinicians and scientists met to debate the clinically relevant, but often controversial issue about whether raised brain temperature after human traumatic brain injury (TBI) should be regarded as "good or bad" for outcome. The objective was to produce a consensus document of views about current temperature measurement and pyrexia treatment. Lectures were delivered by invited speakers with National and International publication track records in thermoregulation, neuroscience, epidemiology, measurement standards and neurocritical care. Summaries of the lectures and workshop discussions were produced from transcriptions of the lectures and workshop discussions. At the close of meeting, there was agreement on four key issues relevant to modern temperature measurement and management and for undergirding of an evidence-based practice, culminating in a consensus statement. There is no robust scientific data to support the use of hypothermia in patients whose intracranial pressure is controllable using standard therapy. A randomized clinical trial is justified to establish if body cooling for control of pyrexia (to normothermia) vs moderate pyrexia leads to a better patient outcome for TBI patients. © 2010 Childs, Wieloch, Lecky, Machin, Harris and Stocchetti.</p>},
  author       = {Childs, Charmaine and Wieloch, Tadeusz and Lecky, Fiona and Machin, Graham and Harris, Bridget and Stocchetti, Nino},
  issn         = {1664-2295},
  keyword      = {Brain temperature,Cooling,Fever,Measurement,Pyrexia},
  language     = {eng},
  publisher    = {ARRAY(0x925ff00)},
  series       = {Frontiers in Neurology},
  title        = {Report of a consensus meeting on human brain temperature after severe traumatic brain injury : Its measurement and management during pyrexia},
  url          = {http://dx.doi.org/10.3389/fneur.2010.00146},
  volume       = {NOV},
  year         = {2010},
}