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Respiratory Tract Infection and Risk of Hospitalization in Children with Congenital Heart Defects During Season and Off-Season : A Swedish National Study

Granbom, Elin; I. FERNLUND, EVA LU ; Sunnegårdh, Jan; Lundell, Bo and Naumburg, Estelle (2016) In Pediatric Cardiology 37(6). p.1098-1105
Abstract

Respiratory tract infections (RTI) are common among young children, and congenital heart defect (CHD) is a risk factor for severe illness and hospitalization. This study aims to assess the relative risk of hospitalization due to RTI in winter and summer seasons for different types of CHD. All children born in Sweden and under the age of two, in 2006–2011, were included. Heart defects were grouped according to type. Hospitalization rates for respiratory syncytial virus (RSV) infection and RTI in general were retrieved from the national inpatient registry. The relative risk of hospitalization was calculated by comparing each subgroup to other types of CHD and otherwise healthy children. The relative risk of hospitalization was increased... (More)

Respiratory tract infections (RTI) are common among young children, and congenital heart defect (CHD) is a risk factor for severe illness and hospitalization. This study aims to assess the relative risk of hospitalization due to RTI in winter and summer seasons for different types of CHD. All children born in Sweden and under the age of two, in 2006–2011, were included. Heart defects were grouped according to type. Hospitalization rates for respiratory syncytial virus (RSV) infection and RTI in general were retrieved from the national inpatient registry. The relative risk of hospitalization was calculated by comparing each subgroup to other types of CHD and otherwise healthy children. The relative risk of hospitalization was increased for all CHD subgroups, and there was a greater increase in risk in summer for the most severe CHD. This included RSV infection, as well as RTI in general. The risk of hospitalization due to RTI is greater for CHD children. Prophylactic treatment with palivizumab, given to prevent severe RSV illness, is only recommended during winter. We argue that information to healthcare staff and parents should include how the risk of severe infectious respiratory tract illnesses, RSV and others, is present all year round for children with CHD.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Congenital heart defect (CHD), Immunoprophylaxis, Palivizumab, Respiratory syncytial virus, Respiratory tract infection
in
Pediatric Cardiology
volume
37
issue
6
pages
8 pages
publisher
Springer
external identifiers
  • Scopus:84964388593
ISSN
0172-0643
DOI
10.1007/s00246-016-1397-4
language
English
LU publication?
yes
id
6ae5b227-ff38-4620-8739-7ece966407b4
date added to LUP
2016-06-18 13:49:40
date last changed
2016-11-17 12:18:53
@misc{6ae5b227-ff38-4620-8739-7ece966407b4,
  abstract     = {<p>Respiratory tract infections (RTI) are common among young children, and congenital heart defect (CHD) is a risk factor for severe illness and hospitalization. This study aims to assess the relative risk of hospitalization due to RTI in winter and summer seasons for different types of CHD. All children born in Sweden and under the age of two, in 2006–2011, were included. Heart defects were grouped according to type. Hospitalization rates for respiratory syncytial virus (RSV) infection and RTI in general were retrieved from the national inpatient registry. The relative risk of hospitalization was calculated by comparing each subgroup to other types of CHD and otherwise healthy children. The relative risk of hospitalization was increased for all CHD subgroups, and there was a greater increase in risk in summer for the most severe CHD. This included RSV infection, as well as RTI in general. The risk of hospitalization due to RTI is greater for CHD children. Prophylactic treatment with palivizumab, given to prevent severe RSV illness, is only recommended during winter. We argue that information to healthcare staff and parents should include how the risk of severe infectious respiratory tract illnesses, RSV and others, is present all year round for children with CHD.</p>},
  author       = {Granbom, Elin and I. FERNLUND, EVA and Sunnegårdh, Jan and Lundell, Bo and Naumburg, Estelle},
  issn         = {0172-0643},
  keyword      = {Congenital heart defect (CHD),Immunoprophylaxis,Palivizumab,Respiratory syncytial virus,Respiratory tract infection},
  language     = {eng},
  month        = {04},
  number       = {6},
  pages        = {1098--1105},
  publisher    = {ARRAY(0xad0b300)},
  series       = {Pediatric Cardiology},
  title        = {Respiratory Tract Infection and Risk of Hospitalization in Children with Congenital Heart Defects During Season and Off-Season : A Swedish National Study},
  url          = {http://dx.doi.org/10.1007/s00246-016-1397-4},
  volume       = {37},
  year         = {2016},
}