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Application of conducting paper for selective detection of troponin

Jagadeesan, Kishore Kumar LU ; Kumar, Saurabh and Sumana, Gajjala (2012) In Electrochemistry Communications 20(1). p.71-74
Abstract

The electrochemically coated conducting paper based point-of-care diagnostics using amperometric sensing principles for troponin detection has been demonstrated in the present report. The cost-effective and stable conducting polymer coating was achieved on papers using screen printing followed by electrochemical deposition techniques for the first time. The cyclic voltammetric analysis has revealed the stable and uniform conducting polyaniline (PANI) coating onto filter papers fabricated using the simple and novel approach. These strips were found to be very sensitive for the futuristic diagnostics and the concept was proved by utilizing these strips for the troponin detection in a wide physiological range (1-100 ng/mL) with sensitivity... (More)

The electrochemically coated conducting paper based point-of-care diagnostics using amperometric sensing principles for troponin detection has been demonstrated in the present report. The cost-effective and stable conducting polymer coating was achieved on papers using screen printing followed by electrochemical deposition techniques for the first time. The cyclic voltammetric analysis has revealed the stable and uniform conducting polyaniline (PANI) coating onto filter papers fabricated using the simple and novel approach. These strips were found to be very sensitive for the futuristic diagnostics and the concept was proved by utilizing these strips for the troponin detection in a wide physiological range (1-100 ng/mL) with sensitivity of 5.5 μA/ng mL - 1 cm - 2. Association constant of the electrode has been found to be 1.2 × 10 13 L mol - 1. © 2012 Elsevier B.V. All rights reserved.

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author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Biosensor, Conducting paper, Polyaniline, Screen-printed electrode, Troponin
in
Electrochemistry Communications
volume
20
issue
1
pages
4 pages
publisher
Elsevier
external identifiers
  • Scopus:84861899176
ISSN
1388-2481
DOI
10.1016/j.elecom.2012.03.041
language
English
LU publication?
no
id
6f5d19d1-16c3-4830-8e8a-dcd294becd73
date added to LUP
2016-05-13 17:03:20
date last changed
2016-10-13 05:08:35
@misc{6f5d19d1-16c3-4830-8e8a-dcd294becd73,
  abstract     = {<p>The electrochemically coated conducting paper based point-of-care diagnostics using amperometric sensing principles for troponin detection has been demonstrated in the present report. The cost-effective and stable conducting polymer coating was achieved on papers using screen printing followed by electrochemical deposition techniques for the first time. The cyclic voltammetric analysis has revealed the stable and uniform conducting polyaniline (PANI) coating onto filter papers fabricated using the simple and novel approach. These strips were found to be very sensitive for the futuristic diagnostics and the concept was proved by utilizing these strips for the troponin detection in a wide physiological range (1-100 ng/mL) with sensitivity of 5.5 μA/ng mL <sup>- 1</sup> cm <sup>- 2</sup>. Association constant of the electrode has been found to be 1.2 × 10 <sup>13</sup> L mol <sup>- 1</sup>. © 2012 Elsevier B.V. All rights reserved.</p>},
  author       = {Jagadeesan, Kishore Kumar and Kumar, Saurabh and Sumana, Gajjala},
  issn         = {1388-2481},
  keyword      = {Biosensor,Conducting paper,Polyaniline,Screen-printed electrode,Troponin},
  language     = {eng},
  number       = {1},
  pages        = {71--74},
  publisher    = {ARRAY(0xac8e788)},
  series       = {Electrochemistry Communications},
  title        = {Application of conducting paper for selective detection of troponin},
  url          = {http://dx.doi.org/10.1016/j.elecom.2012.03.041},
  volume       = {20},
  year         = {2012},
}