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Digital breast tomosynthesis (3D-mammography) screening : A pictorial review of screen-detected cancers and false recalls attributed to tomosynthesis in prospective screening trials

Houssami, Nehmat; Lång, Kristina LU ; Bernardi, Daniela; Tagliafico, Alberto; Zackrisson, Sophia LU and Skaane, Per (2016) In Breast 26. p.34-119
Abstract

This pictorial review highlights cancers detected only at tomosynthesis screening and screens falsely recalled in the course of breast tomosynthesis screening, illustrating both true-positive (TP) and false-positive (FP) detection attributed to tomosynthesis. Images and descriptive data were used to characterise cases of screen-detection with tomosynthesis, sourced from prospective screening trials that performed standard (2D) digital mammography (DM) and tomosynthesis (3D-mammography) in the same screening participants. Exemplar cases from four trials highlight common themes of relevance to screening practice including: the type of lesions frequently made more conspicuous or perceptible by tomosynthesis (spiculated masses, and... (More)

This pictorial review highlights cancers detected only at tomosynthesis screening and screens falsely recalled in the course of breast tomosynthesis screening, illustrating both true-positive (TP) and false-positive (FP) detection attributed to tomosynthesis. Images and descriptive data were used to characterise cases of screen-detection with tomosynthesis, sourced from prospective screening trials that performed standard (2D) digital mammography (DM) and tomosynthesis (3D-mammography) in the same screening participants. Exemplar cases from four trials highlight common themes of relevance to screening practice including: the type of lesions frequently made more conspicuous or perceptible by tomosynthesis (spiculated masses, and architectural distortions); the histologic findings (both TP and FP) of tomosynthesis-only detection; and the need to extend breast work-up protocols (additional imaging including ultrasound and MRI, and tomosynthesis-guided biopsy) if tomosynthesis is adopted for primary screening.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Breast cancer detection
in
Breast
volume
26
pages
16 pages
publisher
Churchill Livingstone
external identifiers
  • Scopus:84961844016
  • WOS:000373112600016
ISSN
1532-3080
DOI
10.1016/j.breast.2016.01.007
language
English
LU publication?
yes
id
7b28cfb6-0f9d-4c29-ae43-3356f6ef4b2a
date added to LUP
2016-04-18 13:54:53
date last changed
2016-12-04 04:50:32
@misc{7b28cfb6-0f9d-4c29-ae43-3356f6ef4b2a,
  abstract     = {<p>This pictorial review highlights cancers detected only at tomosynthesis screening and screens falsely recalled in the course of breast tomosynthesis screening, illustrating both true-positive (TP) and false-positive (FP) detection attributed to tomosynthesis. Images and descriptive data were used to characterise cases of screen-detection with tomosynthesis, sourced from prospective screening trials that performed standard (2D) digital mammography (DM) and tomosynthesis (3D-mammography) in the same screening participants. Exemplar cases from four trials highlight common themes of relevance to screening practice including: the type of lesions frequently made more conspicuous or perceptible by tomosynthesis (spiculated masses, and architectural distortions); the histologic findings (both TP and FP) of tomosynthesis-only detection; and the need to extend breast work-up protocols (additional imaging including ultrasound and MRI, and tomosynthesis-guided biopsy) if tomosynthesis is adopted for primary screening.</p>},
  author       = {Houssami, Nehmat and Lång, Kristina and Bernardi, Daniela and Tagliafico, Alberto and Zackrisson, Sophia and Skaane, Per},
  issn         = {1532-3080},
  keyword      = {Breast cancer detection},
  language     = {eng},
  pages        = {34--119},
  publisher    = {ARRAY(0x688e548)},
  series       = {Breast},
  title        = {Digital breast tomosynthesis (3D-mammography) screening : A pictorial review of screen-detected cancers and false recalls attributed to tomosynthesis in prospective screening trials},
  url          = {http://dx.doi.org/10.1016/j.breast.2016.01.007},
  volume       = {26},
  year         = {2016},
}