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Need for individual cancer risk estimates in X-rayand nuclear medicine imaging

Mattsson, Sören LU (2016) In Radiation Protection Dosimetry 169(1). p.11-16
Abstract

To facilitate the justification of an X-ray or nuclear medicine investigation and for informing patients, it is desirable that the individual patient's radiation dose and potential cancer risk can be prospectively assessed and documented. The current dose-reporting is based on effective dose, which ignores body size and does not reflect the strong dependence of risk on the age at exposure. Risk estimations should better be done through individual organ dose assessments, which need careful exposure characterisation as well as anatomical description of the individual patient. In nuclear medicine, reference biokinetic models should also be replaced with models describing individual physiological states and biokinetics. There is a need to... (More)

To facilitate the justification of an X-ray or nuclear medicine investigation and for informing patients, it is desirable that the individual patient's radiation dose and potential cancer risk can be prospectively assessed and documented. The current dose-reporting is based on effective dose, which ignores body size and does not reflect the strong dependence of risk on the age at exposure. Risk estimations should better be done through individual organ dose assessments, which need careful exposure characterisation as well as anatomical description of the individual patient. In nuclear medicine, reference biokinetic models should also be replaced with models describing individual physiological states and biokinetics. There is a need to adjust population-based cancer risk estimates to the possible risk of leukaemia and solid tumours for the individual depending on age and gender. The article summarises reasons for individual cancer risk estimates and gives examples of methods and results of such estimates.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Radiation Protection Dosimetry
volume
169
issue
1
pages
6 pages
publisher
Nuclear Technology Publishing
external identifiers
  • Scopus:84979083978
ISSN
0144-8420
DOI
10.1093/rpd/ncw034
language
English
LU publication?
yes
id
80f81d05-63f6-4fe4-aa50-d4ed09566217
date added to LUP
2016-09-14 15:09:57
date last changed
2016-09-20 03:00:50
@misc{80f81d05-63f6-4fe4-aa50-d4ed09566217,
  abstract     = {<p>To facilitate the justification of an X-ray or nuclear medicine investigation and for informing patients, it is desirable that the individual patient's radiation dose and potential cancer risk can be prospectively assessed and documented. The current dose-reporting is based on effective dose, which ignores body size and does not reflect the strong dependence of risk on the age at exposure. Risk estimations should better be done through individual organ dose assessments, which need careful exposure characterisation as well as anatomical description of the individual patient. In nuclear medicine, reference biokinetic models should also be replaced with models describing individual physiological states and biokinetics. There is a need to adjust population-based cancer risk estimates to the possible risk of leukaemia and solid tumours for the individual depending on age and gender. The article summarises reasons for individual cancer risk estimates and gives examples of methods and results of such estimates.</p>},
  author       = {Mattsson, Sören},
  issn         = {0144-8420},
  language     = {eng},
  number       = {1},
  pages        = {11--16},
  publisher    = {ARRAY(0xb4181f0)},
  series       = {Radiation Protection Dosimetry},
  title        = {Need for individual cancer risk estimates in X-rayand nuclear medicine imaging},
  url          = {http://dx.doi.org/10.1093/rpd/ncw034},
  volume       = {169},
  year         = {2016},
}