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Gene variance in the nicotinic receptor cluster (CHRNA5-CHRNA3-CHRNB4) predicts death from cardiopulmonary disease and cancer in smokers.

Halldén, Sara LU ; Sjögren, Marketa LU ; Hedblad, Bo LU ; Engström, Gunnar LU ; Hamrefors, Viktor LU ; Manjer, Jonas LU and Melander, Olle LU (2015) In Journal of Internal Medicine 279(4). p.388-398
Abstract
Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking-related diseases such as chronic obstructive pulmonary disease (COPD), peripheral artery disease and lung cancer.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Internal Medicine
volume
279
issue
4
pages
388 - 398
publisher
Wiley-Blackwell
external identifiers
  • PMID:26689306
  • Scopus:84961200060
  • WOS:000372978800008
ISSN
1365-2796
DOI
10.1111/joim.12454
language
English
LU publication?
yes
id
cb7c608e-c1e5-442a-94cd-a45ea904214f (old id 8504120)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26689306?dopt=Abstract
date added to LUP
2016-01-06 11:33:47
date last changed
2016-10-13 04:25:38
@misc{cb7c608e-c1e5-442a-94cd-a45ea904214f,
  abstract     = {Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking-related diseases such as chronic obstructive pulmonary disease (COPD), peripheral artery disease and lung cancer.},
  author       = {Halldén, Sara and Sjögren, Marketa and Hedblad, Bo and Engström, Gunnar and Hamrefors, Viktor and Manjer, Jonas and Melander, Olle},
  issn         = {1365-2796},
  language     = {eng},
  month        = {12},
  number       = {4},
  pages        = {388--398},
  publisher    = {ARRAY(0x99a0680)},
  series       = {Journal of Internal Medicine},
  title        = {Gene variance in the nicotinic receptor cluster (CHRNA5-CHRNA3-CHRNB4) predicts death from cardiopulmonary disease and cancer in smokers.},
  url          = {http://dx.doi.org/10.1111/joim.12454},
  volume       = {279},
  year         = {2015},
}